公开(公告)号：KR1020120122356A

公开(公告)日：2012-11-07

申请号：KR1020110040449

申请日：2011-04-29

Applicant: 박사룡

Inventor： 박사룡

IPC: A63B53/04 ,  A63B53/00

CPC classification number: A63B53/04 ,  A63B2053/0433 ,  A63B2102/32

Abstract: PURPOSE: A golf club is provided to maximize the restitution coefficient of a spring and a head face and to increase the flight distance of a golf ball. CONSTITUTION: A golf club comprises a spring, a shaft, and a grip. The spring is mounted between a crown and a face surface and is made of an elastic metal material. The shaft and grip are mounted in the head which is made by welding the crown and face surface. The crown and face surface are made of a high elastic metal material.

Abstract translation: 目的：提供高尔夫球杆，以最大化弹簧和头部面的恢复系数，并增加高尔夫球的飞行距离。 构成：高尔夫球杆包括弹簧，轴和手柄。 弹簧安装在表冠和表面之间，并由弹性金属材料制成。 轴和把手安装在通过焊接表冠和表面而制成的头部中。 表面和表面由高弹性金属材料制成。

公开(公告)号：KR1020110075133A

公开(公告)日：2011-07-06

申请号：KR1020090131485

申请日：2009-12-28

Applicant: 박사룡

Inventor： 박사룡

IPC: C07D403/12 ,  C07D213/06 ,  A61P37/08

Abstract: PURPOSE: A method for selectively preparing optically active (S)-[(4-chlorophenyl)-2-pyridyl]methanol is provided to selectively hydrogenate (4-chlorophenyl)-2-pyridyl-ketone. CONSTITUTION: A method for preparing (S)-[(4-chlorophenyl)-2-pyridyl]methanol of structural formula I comprises a step of reducing 4-chlorophenyl-2-pyridyl ketone of structural formula II in an organic solvent. The (S)-[(4-chlorophenyl)-2-pyridyl]methanol is an useful intermediate for manufacturing (S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid(general name: Bepotastin) with excellent anti-histamine activity and anti-allergic activity.

Abstract translation: 目的：提供选择性制备光学活性（S） - [（4-氯苯基）-2-吡啶基]甲醇的方法以选择性氢化（4-氯苯基）-2-吡啶酮。 构成：制备结构式I（S） - [（4-氯苯基）-2-吡啶基]甲醇的方法包括在有机溶剂中还原结构式II的4-氯苯基-2-吡啶基酮的步骤。 （S） - [（4-氯苯基）-2-吡啶基]甲醇是制备（S）-4- [4 - [（4-氯苯基）（2-吡啶基）甲氧基]哌啶子基]丁酸（ 一般名称：Bepotastin）具有优异的抗组胺活性和抗过敏活性。

公开(公告)号：KR1020110028207A

公开(公告)日：2011-03-17

申请号：KR1020100049479

申请日：2010-05-27

Applicant: 박사룡

Inventor： 박사룡

IPC: C07D401/10 ,  C07D401/02 ,  C07D401/12

CPC classification number: Y02P20/55 ,  C07D401/12 ,  A61K31/4545 ,  C07D213/26 ,  C07D213/30

Abstract: PURPOSE: A method for preparing (S)-4-[4-[4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid and additive salts thereof are provided. CONSTITUTION: A method for preparing (S)-4-[4-[4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid and additive salts thereof comprises: a step of reacting (-)-4-chlorophenyl-2-pyridyl-methanol of structural formula b with an alkali metal to obtain a (-)-4-chlorophenyl-2-pyridyl-methoxide of an alkali metal of structural formula b'; a step of reacting the compound of chemical formula b' with 4-halogeno-piperidyl)-butanoic acid derivative of structural formula c to obtain a (S)-4-[4-[4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid derivative of structural formula I'; and a step of removing a carboxylic protection group and reacting with organic acid.

Abstract translation: 目的：提供（S）-4- [4- [4-氯苯基]（2-吡啶基）甲氧基]哌啶子基]丁酸及其添加盐的制备方法。 构成：（S）-4- [4- [4-氯苯基]（2-吡啶基）甲氧基]哌啶子基]丁酸及其添加盐的制备方法包括：（ - ） - 4-氯苯基-2 结构式b的吡啶基 - 甲醇与碱金属反应，得到结构式b'的碱金属的（ - ） - 4-氯苯基-2-吡啶基 - 甲醇盐; 使化学式b'的化合物与结构式c的4-卤代 - 哌啶基） - 丁酸衍生物反应，得到（S）-4- [4- [4-氯苯基]（2-吡啶基）甲氧基] 哌啶子基]丁酸衍生物; 以及除去羧基保护基并与有机酸反应的步骤。

公开(公告)号：KR1020110028199A

公开(公告)日：2011-03-17

申请号：KR1020100002579

申请日：2010-01-12

Applicant: 박사룡

Inventor： 박사룡

IPC: C07D401/10 ,  C07D401/02 ,  C07D403/12

CPC classification number: Y02P20/55 ,  C07D401/12 ,  A61K31/4545 ,  C07D211/34 ,  C07D211/38 ,  C07D213/26 ,  C07D213/30

Abstract: PURPOSE: A method for preparing optically active piperidine compounds is provided to ensure stability without hygroscopic property. CONSTITUTION: A method for preparing (S)-4-[4-[4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid of structure formula I comprises: a step of reacting (S)-(-)-4-chlorophenyl-2-pyridyl-methanol of structural formula b with a 4-halogeno-piperidyl)-butanoic acid derivative of structural formula c to obtain a (S)-4-[4-[4-chlorophenyl)(2-pyridyl)methoxy]piperidino] butanoic acid derivative of structural formula I'; a step of removing carboxyl protection group from the derivative of structural formula I'; and a step of reacting with an organic acid.

Abstract translation: 目的：提供光学活性哌啶化合物的制备方法，以确保不吸湿性的稳定性。 构成：结构式I的（S）-4- [4- [4-氯苯基）（2-吡啶基）甲氧基]哌啶子基]丁酸的制备方法包括：（S） - （ - ） - （S）-4- [4- [4-氯苯基]（2-吡啶基） - （4-吡啶基） - 丁酸衍生物的结构式c的4-卤代 - 甲氧基]哌啶子基]丁酸衍生物; 从结构式I'的衍生物中除去羧基保护基团的步骤; 和与有机酸反应的步骤。

公开(公告)号：KR1020080037493A

公开(公告)日：2008-04-30

申请号：KR1020060113878

申请日：2006-11-17

Applicant: 박사룡

Inventor： 박사룡

IPC: A61K9/10

CPC classification number: A61K9/10 ,  A61K31/366 ,  A61K31/40 ,  A61K31/436 ,  A61K31/505 ,  A61K47/10 ,  B82Y5/00

Abstract: A co-dissolved mixture of a water-insoluble drug is provided to show enough medicinal effect with a little amount of the drug because of the nano-sized drug being dispersed into a polyhydric alcohol ultra-finely and also show rapid medicinal efficacy. A co-dissolved mixture is characterized in that an ultra-fine nano-sized drug which is hard to be solved in water is dispersed into a polyhydric alcohol or a diluent is further evenly dispersed into the dispersion. In the mixture, the drug is selected from the group consisting of orlistat, atorvastatin and a salt thereof, atorvastatin lactone-type, rosuvastatin and a salt thereof, pivastatin and a salt thereof, simvastatin and tacrolimus, and the polyhydric alcohol is selected from the group consisting of ethyleneglycol, propyleneglycol, glycerin, polyethyleneglycol, monosaccharide and disaccharide.

Abstract translation: 提供了一种溶于水的不溶性药物的混合溶液，由于纳米级药物被超细分散在多元醇中并显示出快速的药用效能，因此用少量的药物显示出足够的药用效果。 共溶解混合物的特征在于，难以在水中溶解的超细纳米尺寸药物分散在多元醇中，或稀释剂进一步均匀地分散在分散体中。 在该混合物中，药物选自奥利司他，阿托伐他汀及其盐，阿托伐他汀内酯型，瑞舒伐他汀及其盐，妥他他汀及其盐，辛伐他汀和他克莫司，多元醇选自 由乙二醇，丙二醇，甘油，聚乙二醇，单糖和二糖组成的组。

公开(公告)号：KR1020060028790A

公开(公告)日：2006-04-03

申请号：KR1020060017147

申请日：2006-02-22

Applicant: 박사룡 ,  송태희

Inventor： 박사룡 ,  송태희

IPC: B65D33/24 ,  B65D33/25 ,  B65D33/16

CPC classification number: B65D33/2541 ,  B65D33/22 ,  B65D33/2508 ,  B65D75/20

Abstract: 본 발명은 암프로파일 베이스를 구성하는 열가소성 수지 재질과 수프로파일 베이스를 구성하는 열가소성 수지 재질을 물성이 상이한 재질을 사용하여 제조하고, 열가소성 플라스틱 팩의 재질과 같은 종류의 열가소성 수지를 플라스틱 종류가 상이한 재질로 제조한 암프로파일 베이스 부재 또는 수프로파링 베이스 부재의 외부면에 형성시켜서 지퍼 스트립을 제공하는 것이며, 본 발명의 지퍼스트립은 열가소성 플라스틱 팩의 상단면에 횡으로 배치하여 열용착시에 암수프로파일 베이스 부재 상호간에는 열용착이 일어나지 않고 암수프로파일 베이스 부재의 외부면과 팩의 내부면에만 열용착에 의하여 접착되며, 지퍼의 개폐시에 부드럽게 개폐할 수 있다.
물성이 상이한 플라스틱, 지퍼 스트립

公开(公告)号：KR2019940022535U

公开(公告)日：1994-10-20

申请号：KR2019930004483

申请日：1993-03-25

Applicant: 박사룡 ,  이만종

Inventor： 박사룡 ,  이만종

IPC: B65D27/24

Abstract: 본고안은개봉용실이부착된봉투에관한것으로, 봉투의내측면일단에실이접착또는재봉되어서이 실을잡아당김으로써용이하게봉투가개봉될수 있도록된 것이다.

公开(公告)号：KR1019920021007A

公开(公告)日：1992-11-21

申请号：KR1019920010365

申请日：1992-06-15

Applicant: 박사룡

Inventor： 박사룡

IPC: A46B7/08

公开(公告)号：KR1019910001662B1

公开(公告)日：1991-03-18

申请号：KR1019880016349

申请日：1988-12-08

Applicant: 박사룡

Inventor： 박사룡

IPC: B60R22/44

Abstract: The safety belt improves a belt retractor by having a winding power braking means. The safety belt includes; emergency braking means with a dog device, having ratchet gear operated by braking lever; winding power controlling means by actuation of snatching; ratchet gears (32,32') formed at winding shaft (5); ratchet gear (11) having ratchet formed opposite to the gearing direction of ratchet gears (32,32').

Abstract translation: 安全带通过具有绕线动力制动装置来改善皮带卷收器。 安全带包括 具有狗装置的紧急制动装置，具有由制动杆操作的棘轮; 绕组电力控制装置通过致动抓取; 形成在卷轴（5）上的棘轮（32,32'）; 具有与棘轮（32,32'）的齿轮方向相反的棘轮的棘轮（11）。

公开(公告)号：KR2019900019793U

公开(公告)日：1990-12-12

申请号：KR2019890006930

申请日：1989-05-26

Applicant: 박사룡

Inventor： 박사룡

IPC: A46B13/08