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公开(公告)号:WO2023004336A1
公开(公告)日:2023-01-26
申请号:PCT/US2022/073915
申请日:2022-07-20
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: RYAN, Owen , FENG, Lei
Abstract: Described herein are Schizosaccharomyces pombe yeast strains genetically engineered to produce lactic acid, wherein the best performing strains have two copies of a heterologous lactate dehydrogenase gene codon optimized for expression in S. pombe in combination with inactivation of specific alleles encoding pyruvate decarboxylase (PDC), alcohol dehydrogenase (ADH) and glycerol 3 phosphate dehydrogenase (GDP). The specific alleles that are deleted are PDC201, ADH1 ADH4, and/or GDP1. The exogenous LDH genes are expressed by the S. pombe actin promoter discovered to be a constitutive high activity promoter, which may be operably linked to any gene of interest for expression in S. pombe. Also disclosed are several variant LDH genes from a variety of species that produce high levels of lactic acid when expressed in S. pombe cells.
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公开(公告)号:WO2022187745A1
公开(公告)日:2022-09-09
申请号:PCT/US2022/019172
申请日:2022-03-07
Applicant: ARCHER-DANIELS-MIDLAND COMPANY
Inventor: LEE, Jinsha , LI, Wei , WYATT, Ross
Abstract: Methods of binding ingredients of a meat alternative product are disclosed. One method comprises mixing a first hydrocolloid and a second hydrocolloid with a protein, thus producing the meat alternative product and forming the meat alternative product to a desired shape. Another method includes mixing a first hydrocolloid, a second hydrocolloid, and a protein, thus producing the meat alternative product and hydrating the meat alternative product. Products produced by the methods are also disclosed.
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公开(公告)号:WO2022094110A1
公开(公告)日:2022-05-05
申请号:PCT/US2021/057090
申请日:2021-10-28
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: HELD, Sophie , KOLPIN-GUSTAFSON, Kathryn
IPC: A23C19/032 , A23C19/068
Abstract: Non-animal protein-based cheeses and processes for producing are disclosed. A process of producing a cheese base includes mixing a hydrated non-animal protein with a fat, thus producing a mixture, and mixing an acid with the mixture to form a curd. The curd may be used to form soft or hard cheeses. The curd may be mixed with different ingredients, thus producing a mixture. The mixture may be mixed, thus producing a cheese composition and placed into a mold.
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公开(公告)号:WO2022076464A1
公开(公告)日:2022-04-14
申请号:PCT/US2021/053638
申请日:2021-10-05
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: WICKLUND, Lori , GROOS, Jeremie
Abstract: A process for producing degummed, fatty acid-depleted, bleached and deodorized palm oil with no altered solid fat content and containing 3-MCPD and 2-MCPD in an amount of less than 2.5mg/kg; GE in an amount of less than 1.0mg/kg; and DAK in an amount of less than 25.0mg/kg is provided. The disclosed process is a quick, cost-effective and easily scalable process for producing refined palm oil of high quality.
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公开(公告)号:WO2022035610A1
公开(公告)日:2022-02-17
申请号:PCT/US2021/043728
申请日:2021-07-29
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: TABER, Iman , STENSRUD, Kenneth F. , HOFFMAN, William Christopher
IPC: C07D307/46 , C07D307/68 , C07B63/00
Abstract: Methods are disclosed for the purification of crude compositions comprising 2,5-furandicarboxylic acid, dimethyl ester (FDME) or other diester derivatives (e.g., dialkyl ester derivatives) of 2,5-furandicarboxylic acid (FDCA), by crystallization. In this regard, certain solvents, and classes of solvents, have been discovered to promote the selective crystallization of FDME over impurities often generated in its production by FDCA esterification and other upstream processing steps. Importantly, certain impurities that are selectively removed include those that would otherwise be detrimental to the color and/or color stability of the purified composition. Other improvements in crystallization reside in the use of techniques such as liquid-liquid extraction and pre-treatment of the crystallization solution by contact with a solid medium.
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公开(公告)号:WO2021248077A1
公开(公告)日:2021-12-09
申请号:PCT/US2021/036018
申请日:2021-06-04
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: MA, Chi-Cheng , BRAZDIL, James , LUO, Hao
IPC: B01D11/04 , C02F1/26 , C02F1/66 , C07C303/02 , C07C303/24
Abstract: A process comprises continuously adding a first stream and a second stream to a sulfonation vessel, wherein the first stream comprises aminoethanol sulfate ester (AES) and the second stream comprises an aqueous solution of sodium sulfite (Na2SO3). The process comprises continuously mixing the AES and the aqueous solution of Na2SO3 in the sulfonation vessel, thus producing a mixture. The process comprises continuously subjecting the mixture to heat in the presence of an inert gas, thus converting the AES to the taurine via sulfonation. In an aspect, the AES has a residence time of no more than four hours in the sulfonation vessel. In an aspect the heating step is conducted at a temperature of at least 115° C and a pressure of at least 200 psi.
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公开(公告)号:WO2021231089A1
公开(公告)日:2021-11-18
申请号:PCT/US2021/029660
申请日:2021-04-28
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: COLLINS, William J. , TERRIAN, Josh , BRAZDIL, James , MARTIN, Kevin
Abstract: Various processes for the pyrolysis of carbohydrates to prepare products such as glycolaldehyde are described. Also, various catalysts and processes for preparing catalysts useful for carbohydrate pyrolysis are described.
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公开(公告)号:WO2021119532A1
公开(公告)日:2021-06-17
申请号:PCT/US2020/064673
申请日:2020-12-11
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: SANBORN, Alexandra , AYOUB, Ali , BASEETH, Shireen , HALALIPOUR, Ali , GHOTRA, Baljit
Abstract: A method of forming an ultra-fine starch/flour product comprises at least one of (a) or (b), wherein (a) comprises heating a mixture of water and native/modified starch/flour, and extruding the mixture with a screw configuration comprising in series at least one low-shear forward conveying screw and at least one high-shear mixing screw to produce an extrudate. Step (b) comprises forming a mixture of water, a lipid, and native/modified starch/flour, and drying the mixture to produce a dried lipid starch/flour intermediate. The starting starch/flour may be milled prior or after steps (a) or (b). The ultra-fine starch/flour particle product has a higher water solubility as compared to a starch/flour particle product that is produced with a screw configuration devoid of a high shear mixing screw, or a starch/flour intermediate produced in (b) without a lipid. In an embodiment, the method is devoid of chemical or enzyme reaction.
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公开(公告)号:WO2018236950A1
公开(公告)日:2018-12-27
申请号:PCT/US2018/038418
申请日:2018-06-20
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: ANKLAM, Pam , HOFFMAN, William Chris , SCHULTZ, Mitchell , SOPER, John G.
IPC: B01D15/36 , B01J43/00 , C07C51/47 , C07C59/105 , C07C59/285 , G01N30/02
Abstract: A method is provided for separating a dicarboxylic acid product from a mixture containing such dicarboxylic acids. The method involves: providing a dicarboxylic acid-containing mixture of which at least 35% of the carboxylic acid content of the mixture is a dicarboxylic acid product of interest; running an extraction of said dicarboxylic acid-containing mixture through a chromatographic column configured with an amphoteric resin, such that the dicarboxylic acid product elutes preferentially from the dicarboxylic acid-containing mixture. In certain embodiments, the dicarboxylic acid product of interest can be a glucaric or gluconic acid product from a mixture of either or both of these with still other carboxylic acids.
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公开(公告)号:WO2018236948A1
公开(公告)日:2018-12-27
申请号:PCT/US2018/038415
申请日:2018-06-20
Applicant: ARCHER DANIELS MIDLAND COMPANY
Inventor: ANKLAM, Pam , HOFFMAN, William Chris , HOWARD, Stephen J. , SANBORN, Alexandra , SCHULTZ, Mitchell , SOPER, John G.
IPC: C07D307/40
Abstract: The present invention relates to a process for making the esters of 2,5-furandicarboxylic acid, and particularly the dimethyl, diethyl or dipropyl esters of FDCA for use as monomers in the production of polyesters and other types of polymers with biobased content, comprising: reacting an aqueous feed comprising glucaric acid with a high boiling first alcohol in the presence of an acid catalyst and with removing water during the reaction, to form a first product mixture comprising a first ester of FDCA and the high boiling first alcohol; removing unreacted high boiling first alcohol from the first product mixture; combining the first ester of FDCA and the high boiling first alcohol with a lower boiling second alcohol selected from the group consisting of methanol, ethanol, isopropanol and n-propanol; transesterifying the first ester with the lower boiling second alcohol to form a second product mixture comprising a second ester of FDCA with the lower boiling second alcohol; and recovering the second ester of FDCA with the lower boiling second alcohol.
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