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11.A NOVEL PROCESS FOR MAKING ALISKIREN, ITS NOVEL INTERMEDIATES AND CERTAIN NOVEL COMPOUNDS 审中-公开
Title translation: 制造阿利昔宁的新方法,其新的中间体和某些新化合物公开(公告)号:WO2011064790A1
公开(公告)日:2011-06-03
申请号:PCT/IN2010/000086
申请日:2010-02-15
Applicant: AVRA LABORATORIES PVT. LTD , RAMARAO, Chandrashekar , MICHEL, Patrick, Thomas , NAVAKOTI, Rajasekhar , NANDIPATI, Rama, Devi , RAO, Ramakrishna
Inventor: RAMARAO, Chandrashekar , MICHEL, Patrick, Thomas , NAVAKOTI, Rajasekhar , NANDIPATI, Rama, Devi , RAO, Ramakrishna
IPC: C07C237/22 , C07C231/14 , C07D317/10 , C07D317/20 , C07D317/26
CPC classification number: C07C237/22 , C07C271/22 , C07D207/08 , C07D307/33 , C07D307/58 , C07D317/20 , C07D317/26 , C07D405/04
Abstract: A novel process for making Renin inhibitors like Aliskiren is disclosed. Its novel intermediate compounds and method of making them are also disclosed.
Abstract translation: 公开了一种制造肾素抑制剂如阿利吉仑的新方法。 还公开了其新型中间体化合物及其制备方法。
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公开(公告)号:US10392364B2
公开(公告)日:2019-08-27
申请号:US15520980
申请日:2015-08-11
Applicant: AVRA LABORATORIES PVT. LTD.
Inventor: Ramakrishna Rao , Ramadevi Nandipati , Ravi Gooda , Mukesh Padmakar Shewalkar , Venkat Vasantrao Bhadke
IPC: C07D401/04
Abstract: Disclosed herein is an improved process for preparation of Lenalidomide and crystalline polymorphic forms thereof.
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13.METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES 有权
Title translation: 法关键中间体喜树碱的生产合成公开(公告)号:EP1910269B1
公开(公告)日:2013-09-18
申请号:EP05796470.2
申请日:2005-09-27
Applicant: Avra Laboratories PVT. Ltd.
Inventor: ALLA, Venkata, Rama, Rao
IPC: C07C209/36 , C07C201/08 , C07C205/45
CPC classification number: C07C221/00 , C07C29/40 , C07C45/305 , C07C201/08 , C07C201/12 , C07C205/45 , C07D491/22 , C07C225/22 , C07C33/483 , C07C33/46 , C07C49/807
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14.METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES 有权
Title translation: 法关键中间体喜树碱的生产合成公开(公告)号:EP1910269A2
公开(公告)日:2008-04-16
申请号:EP05796470.2
申请日:2005-09-27
Applicant: Avra Laboratories PVT. Ltd.
Inventor: ALLA, Venkata, Rama, Rao
IPC: C07C209/36 , C07C201/08 , C07C205/45
CPC classification number: C07C221/00 , C07C29/40 , C07C45/305 , C07C201/08 , C07C201/12 , C07C205/45 , C07D491/22 , C07C225/22 , C07C33/483 , C07C33/46 , C07C49/807
Abstract: The present invention discloses a process for efficient production of 2-amino-5- hydroxypropiophenone corresponding to the AB ring part of camptothecin (CPT) skelton, which is a key intermediate useful for the total synthesis of camptothecin analogs including 7-Ethyl-10-hydroxy camptothecin and novel intermediates thereof.
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