公开(公告)号：JP2011105741A

公开(公告)日：2011-06-02

申请号：JP2011013921

申请日：2011-01-26

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： HERMIDA OCHOA ELIAS HUMBERTO

IPC: A61K31/737 ,  A61L27/00 ,  A61K20060101 ,  A61K9/06 ,  A61K31/715 ,  A61K31/728 ,  A61K31/738 ,  A61P20060101 ,  A61P19/02 ,  A61P41/00 ,  A61P43/00 ,  C08B37/08

CPC classification number: A61K31/728 ,  A61K9/0024 ,  A61K31/737 ,  A61L27/26 ,  A61L2430/24 ,  A61K2300/00 ,  C08L5/08

Abstract: PROBLEM TO BE SOLVED: To provide a new method in use of a composition for treating chondropathy in osteoarthropathy. SOLUTION: The method includes a drip-feed administration in the joint, of a viscoelastic solution comprising sodium hyaluronate and sodium chondroitin sulfate. The molecular weight of chondroitin sulfate or the pharmacologically acceptable salt thereof is 20,000 to 50,000 daltons, and that of sodium hyaluronate is 500,000 to 1,000,000 daltons. The composition has viscosity of 20,000-60,000 cps. COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 待解决的问题：提供使用治疗骨关节病中软骨病的组合物的新方法。 解决方案：该方法包括在接头中给予包含透明质酸钠和硫酸软骨素钠的粘弹性溶液的滴注。 硫酸软骨素或其药理学可接受的盐的分子量为20,000至50,000道尔顿，透明质酸钠的分子量为500,000至1,000,000道尔顿。 组合物的粘度为20,000-60,000cps。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011101810A

公开(公告)日：2011-05-26

申请号：JP2011006303

申请日：2011-01-14

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： BOUKHNY MIKHAIL ,  DACQUAY BRUNO ,  FANNEY DOUGLAS M

IPC: A61F9/007 ,  A61B18/00

Abstract: PROBLEM TO BE SOLVED: To satisfy the needs for a method that allows pulse shapes and durations to be manipulated for different phacoemulsification applications and procedures. SOLUTION: The method of generating energy used for an ophthalmic surgical device includes steps of programming a linear rise component, programming a linear decay component, and generating pulses including multi-segment, wherein a first segment has the linear rise component which increases from a first amplitude to a second amplitude, a second segment begins at the end of first segment and is the second amplitude, a third segment has the linear decay component which decreases from the second amplitude to the third amplitude, and the linear rise and decay components are programmed separately from a natural rise and natural decay which occur due to switching an amplifier on and off to generate pulses. COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：满足允许针对不同晶状体乳化应用和程序操纵脉冲形状和持续时间的方法的需要。 解决方案：用于眼科手术装置的产生能量的方法包括编程线性上升分量，编程线性衰减分量以及产生包括多分段的脉冲的步骤，其中第一分段具有增加的线性上升分量 从第一幅度到第二幅度，第二段在第一段的末端开始并且是第二幅度，第三段具有从第二幅度减小到第三幅度的线性衰减分量，并且线性上升和衰减 组件与自然上升和自然衰减分开编程，这是由于打开和关闭放大器以产生脉冲而发生的。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011026355A

公开(公告)日：2011-02-10

申请号：JP2010253317

申请日：2010-11-11

Applicant: Alcon Inc ,  アルコン,インコーポレイテッド

Inventor： CHOWHAN MASOOD A ,  CHEN HUAGANG

IPC: A61K47/38 ,  A61K9/00 ,  A61K9/08 ,  A61K47/34 ,  A61K47/36 ,  A61P27/02

CPC classification number: A61K31/765 ,  A61K9/0048 ,  Y10S514/912 ,  Y10S514/913 ,  Y10S514/915

Abstract: PROBLEM TO BE SOLVED: To provide ophthalmic compositions containing three polymers.
SOLUTION: There are provided ophthalmic compositions suitable for use as artificial tears, or ophthalmic compositions suitable for use as vehicles for ophthalmic drugs. The compositions include a combination of three polymers that have a synergistic effect on viscosity. The three polymers are hydroxypropylmethylcellulose, and a combination of two polymers. The combination of the two polymers is selected from the group of combinations consisting of guar gum, and a carboxyvinyl polymer; guar gum, and a hydroxyethylcellulose; guar gum, and dextran; hydroxyethylcellulose, and carboxyvinyl polymer; and dextran, and carboxyvinyl polymer.
COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供含有三种聚合物的眼用组合物。 提供适合用作人造眼泪的眼用组合物，或适合用作眼科药物的眼用组合物。 组合物包括对粘度具有协同作用的三种聚合物的组合。 三种聚合物是羟丙基甲基纤维素和两种聚合物的组合。 两种聚合物的组合选自瓜尔胶和羧基乙烯基聚合物组合的组合; 瓜尔胶和羟乙基纤维素; 瓜尔胶和葡聚糖; 羟乙基纤维素和羧基乙烯基聚合物; 和葡聚糖，以及羧乙烯基聚合物。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2008307384A

公开(公告)日：2008-12-25

申请号：JP2008151500

申请日：2008-06-10

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： HICKINGBOTHAM DYSON W

IPC: A61F9/007

CPC classification number: A61F9/00736 ,  A61B17/3462

Abstract: PROBLEM TO BE SOLVED: To provide a self sealing cannula and an aperture closure cannula relating to ophthalmic surgical equipment and more particularly to posterior segment ophthalmic surgical equipment. SOLUTION: This cannula is provided having a body, a sealing disc, and a cap. The sealing disc is located within the body and is compressed by the cap. An angled cut in the sealing disc allows microsurgical instruments to be inserted through the cannula into the eye. After removal, the cut in the sealing disc closes, preventing the loss of intraocular pressure. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种与眼科外科设备相关的自密封插管和孔封套，更具体地涉及后段眼科手术设备。 解决方案：该插管设置有主体，密封盘和盖。 密封盘位于主体内并被盖子压缩。 密封盘中的角度切割允许显微外科器械通过套管插入眼睛。 去除后，密封盘中的切口关闭，防止眼压下降。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008307376A

公开(公告)日：2008-12-25

申请号：JP2008107753

申请日：2008-04-17

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： DOWNER DAVID A ,  TJIA KHIUN F

IPC: A61F2/16 ,  A61F9/007

CPC classification number: A61F2/1678

Abstract: PROBLEM TO BE SOLVED: To provide a cartridge for a lens delivery system, which provides an aid for an incision to reduce a tendency of wound damage through tearing.
SOLUTION: The cartridge for an intraocular lens (IOL) delivery system is provided that is specifically designed to aid in wound assisted IOL delivery. The distal tip of a nozzle has an extended canopy that serves to open the incision and support the IOL. Peripheral protrusions, flanges, or stops extending laterally from a side of the distal tip provide a positive depth limitation, and prevent the full insertion of the nozzle into the incision. In addition, the protrusion provides support to the incision to reduce the tendency of wound damage through tearing.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于透镜输送系统的盒，其为切口提供帮助以通过撕裂减少伤口损伤的倾向。 解决方案：提供专门设计用于辅助IOL输送的人工晶状体（IOL）输送系统的药筒。 喷嘴的远端具有用于打开切口并支撑IOL的延伸冠层。 从远端侧面横向延伸的周边突起，凸缘或止挡提供正深度限制，并且防止喷嘴完全插入切口。 此外，突起为切口提供支撑，以通过撕裂减少伤口损伤的倾向。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008209907A

公开(公告)日：2008-09-11

申请号：JP2008012710

申请日：2008-01-23

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： SMITH RONALD T ,  AULD JACK R ,  LIN DEAN Y

IPC: F21V29/15 ,  G02B6/26 ,  A61B18/20 ,  A61F9/007 ,  G02B6/42

CPC classification number: G02B6/0008 ,  A61F9/007 ,  G02B6/241 ,  G02B6/32

Abstract: PROBLEM TO BE SOLVED: To provide illumination probes having plastic optical fibers with thermally robust distal tips.
SOLUTION: A plastic optical fiber 202 is bonded to a high temperature distal part to form a thermally robust illumination probe 200. The distal part is short in length, is made of a high temperature material(s), has a proper shape for guiding light in a desired application, and may be coated with a reflective coating to ensure that the light rays trapped within the part of the distal part do not escape when the side of the distal part comes into contact with high refractive index or absorptive materials. The distal part may be made of high temperature material(s) such as high temperature plastic rods, glass optical fibers 206, and so on. The distal end may be tapered or sculpted to a desired configuration. The plastic optical fiber 202 and the high temperature distal part may be joined, using an optical adhesive 204, inside a steel cannula 208, a plastic hub, an optical connector, etc.
COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供具有热稳定的远端尖端的具有塑料光纤的照明探针。 解决方案：将塑料光纤202接合到高温远端部分以形成耐热的照明探测器200.远端部分的长度较短，由高温材料制成，具有适当的形状 用于在期望的应用中引导光，并且可以涂覆有反射涂层，以确保当远端部分的侧面与高折射率或吸收材料接触时捕获在远端部分的部分内的光线不会逸出 。 远端部分可以由诸如高温塑料杆，玻璃光纤206等的高温材料制成。 远端可以是锥形的或雕刻成所需的构型。 塑料光纤202和高温远端部分可以使用光学粘合剂204在钢插管208，塑料毂，光学连接器等内部接合。（C）2008，JPO和INPIT

公开(公告)号：JP2008194465A

公开(公告)日：2008-08-28

申请号：JP2008021389

申请日：2008-01-31

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： ATTINGER JUERG

IPC: A61F9/007

CPC classification number: A61F9/00736 ,  A61B17/3421 ,  A61B2017/00349 ,  A61B2017/2845 ,  A61B2017/2924 ,  A61B2017/305 ,  A61B2017/3492

Abstract: PROBLEM TO BE SOLVED: To provide a thin gauge surgical probe, and further, a thin gauge surgical probe having resistance against bending. SOLUTION: The thin gauge surgical probe is provided with a retractable reinforcing sleeve. When the probe is inserted into the eye, through the trocar cannula, the trocar cannula is removably attached to the distal end of the sleeve, and functions as a reinforcing device. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种薄型手术探针，以及一种具有抗弯曲能力的薄型手术探针。

解决方案：薄型手术探针设有可缩回的加强套管。 当探针插入到眼睛中时，通过套管针插管，套针套管可移除地附接到套筒的远端，并且用作加强装置。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2008168130A

公开(公告)日：2008-07-24

申请号：JP2008001885

申请日：2008-01-09

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： HONG KAREN

IPC: A61F9/007

CPC classification number: A61M3/0283 ,  A61B2090/0813 ,  A61F9/00745 ,  A61M1/0084 ,  A61M2210/0612

Abstract: PROBLEM TO BE SOLVED: To provide an irrigation/aspiration tip, reducing the possibility of breaking rear coating film. SOLUTION: This irrigation/aspiration tip has a relatively rigid cannula, which is attached to a hub and an open end opposite to the hub. A soft elastomer or rubber-made sleeve is removably covered coaxially with the tip. The sleeve forms a gap between the sleeve and the cannula allowing irrigation flow. The distal end of the sleeve is closed by a cap reduced in bore diameter. The reduced bore diameter seals the distal end of the cannula. The relatively soft cap reduces the possibility of breakage of the rear coating film during cleaning up cortex and polishing the coating film. The cannula can be re-sterilized over and over again by detaching the sleeve, so that the cannula can be reused over and over again. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供冲洗/抽吸尖端，降低打破后涂膜的可能性。 解决方案：该灌注/抽吸尖端具有相对刚性的插管，其连接到轮毂和与轮毂相对的开口端。 柔软的弹性体或橡胶制的套筒与尖端同轴地可移除地覆盖。 套筒在套管和插管之间形成间隙，允许冲洗流动。 套筒的远端由孔直径减小的盖封闭。 减小的孔径密封套管的远端。 相对软的帽减少了在清洁皮质和抛光涂膜期间后涂膜破裂的可能性。 套管可以通过分离套管一次又一次地重新消毒，使得套管可以重复使用。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2008093444A

公开(公告)日：2008-04-24

申请号：JP2007262626

申请日：2007-10-05

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： SMITH RONALD T

IPC: A61B19/00 ,  A61F9/007 ,  F21V8/00 ,  F21Y101/00

CPC classification number: A61B3/0008 ,  A61B90/30 ,  A61B2090/306 ,  A61F9/007

Abstract: PROBLEM TO BE SOLVED: To provide a method and system for extending the service life of an ophthalmic illumination system.
SOLUTION: According to one embodiment, the ophthalmic illuminator comprises: an illumination source which produces an arc; a lens for focusing light produced by the illumination source arc; and an optical fiber for carrying the focused light to a surgical site in an eye. The illumination source is positioned offset from a longitudinal axis of the optical fiber to compensate for shifting of the illumination source arc over time. The offset position can be such that the illumination source is positioned in a vertically offset position from the longitudinal axis of the optical fiber. The longitudinal axis corresponds to the optical path axis of the optical fiber. The ophthalmic illuminator can further comprise a reflector for reflecting the light produced by the illumination source arc, wherein the reflector is positioned offset from the illumination source to decrease the rate of erosion of an illumination source cathode.
COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种延长眼科照明系统的使用寿命的方法和系统。 解决方案：根据一个实施例，眼用照明器包括：产生电弧的照明源; 用于聚焦由照明源电弧产生的光的透镜; 以及用于将聚焦光携带到眼睛中的手术部位的光纤。 照明源定位成偏离光纤的纵向轴线，以补偿照明源电弧随时间的移动。 偏移位置可以使得照明源位于离光纤的纵向轴线的垂直偏移位置。 纵轴对应于光纤的光路轴。 眼用照明器还可以包括用于反射由照明源弧产生的光的反射器，其中反射器定位成偏离照明源，以降低照明源阴极的侵蚀速率。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2008080126A

公开(公告)日：2008-04-10

申请号：JP2007249824

申请日：2007-09-26

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： WILLIAMS DAVID LLOYD

IPC: A61F9/007

CPC classification number: F16K1/12

Abstract: PROBLEM TO BE SOLVED: To provide a valve system comprising a valve structure in which the valve is normally closed. SOLUTION: The normally closed valve can comprise a circular valve seal face formed by the underside of a rim of an elastomeric valve boss and a circular valve seat, which is formed by the rim of a through hole molded into, for example, a plastic cassette, so that the valve seal face, the valve seat, and the through hole are concentric. The valve boss can be a hollow "mushroom" shaped valve boss, or a conical-shaped valve boss. If no force is applied to the inside surface of the valve boss, no fluid can pass through the valve as the valve seal face rests against the valve seat as a result of the steady free load created by the stretch of the valve boss over the slightly longer through hole. When a force is applied to the inside surface of the valve boss, the valve seal face is displaced from the valve seat, allowing a fluid between the valve seal face and the valve seat and then to pass through the valve boss and the inside surface of the through hole. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种阀系统，其包括阀门结构，阀门是常闭的。 解决方案：常闭阀可以包括由弹性阀凸台的边缘的下侧形成的圆形阀密封面和圆形阀座，该圆形阀座由通孔的边缘模制成例如， 一个塑料盒，使得阀门密封面，阀座和通孔是同心的。 阀门凸台可以是一个中空的“蘑菇”形阀门，也可以是一个锥形阀门。 如果阀座的内表面没有施加力，由于由于阀座的拉伸产生的稳定的自由载荷在稍微的位置上，阀密封面靠在阀座上，所以没有流体可以通过阀门 更长的通孔。 当将力施加到阀座的内表面时，阀密封面从阀座移位，允许阀密封面和阀座之间的流体通过阀凸台和内表面 通孔。 版权所有（C）2008，JPO＆INPIT