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    METHOD FOR PREPARING GELS
    13.
    发明专利
    METHOD FOR PREPARING GELS 未知

    公开(公告)号：CA2467275A1

    公开(公告)日：2003-05-22

    申请号：CA2467275

    申请日：2002-11-14

    Applicant: BIOMATERA INC

    Inventor： LAPOINTE PATRICK ,  GAYET JEAN-CHARLES JACQUES ,  MASARO LAURENT

    IPC: A61K9/06 ,  A61K8/02 ,  A61K8/06 ,  A61K8/37 ,  A61K8/39 ,  A61K8/72 ,  A61K8/81 ,  A61K9/107 ,  A61K47/34 ,  C08J3/03 ,  C08J3/075 ,  C08L67/04 ,  C08L71/02 ,  C08L101/16

    Abstract: The formation of a cream and gel is described using a biopolymer, such as a polyhydroxyalkanoate (PHA), a polylactide (PLA), a polylactideglycolide (PLG A) and a polyglycoside (PGA), or a derivative thereof, in a latex form with the addition of a binder, which is generally an amphiphilic chemical entity. An hydrophobic domain of the amphiphilic chemical entity interacts with at leas t one biopolymer forming a water soluble complex, while the hydrophilic domain of the amphiphilic chemical entity maintains the soluble complex in suspensi on in an aqueous solution, which after proper heating becomes a gel or a cream. As a result, a versatile gel or cream is created with different compositions and textures that are obtained based on the nature of the binder used and th e ratio of biopolymers and binder(s).

    BIODEGRADABLE BONE IMPLANT MATERIAL
    16.
    发明专利
    BIODEGRADABLE BONE IMPLANT MATERIAL 未知

    公开(公告)号：CA2516728C

    公开(公告)日：2014-05-20

    申请号：CA2516728

    申请日：2003-02-19

    Applicant: BIOMATERA INC

    Inventor： LAPOINTE PATRICK ,  MASARO LAURENT

    IPC: A61L27/58 ,  A61K6/838 ,  A61K6/891 ,  A61L24/00 ,  A61L24/04 ,  A61L27/26

    Abstract: The present invention provides a method for making biodegradable and bioresorbable biomaterials that are also characterized by its malleability. Any desired shape can be obtained from this material, resulting from the specific composition of this invention. Therefore, the biomaterial of the present invention is very well suited to be used as in preparation of implants for dental applications, or as in the case of difficult accessible sites such as bone cavities. Composition of the biomaterial comprises an hydrophobic biopolymer, a compound having both hydrophilic and hydrophobic properties, bone regenerative entity that help in the bone regeneration. In addition, these biomaterials can be used as vehicle for the release of biologically active entities or drugs, such as growth factors or analgesics for example.

    METHOD FOR PREPARING GELS
    17.
    发明专利
    METHOD FOR PREPARING GELS 未知

    公开(公告)号：CA2467275C

    公开(公告)日：2012-09-11

    申请号：CA2467275

    申请日：2002-11-14

    Applicant: BIOMATERA INC

    Inventor： MASARO LAURENT ,  LAPOINTE PATRICK ,  GAYET JEAN-CHARLES JACQUES

    IPC: A61K9/06 ,  C08L67/04 ,  A61K8/02 ,  A61K8/06 ,  A61K8/37 ,  A61K8/39 ,  A61K8/72 ,  A61K8/81 ,  A61K9/107 ,  A61K47/34 ,  C08J3/03 ,  C08J3/075 ,  C08L71/02 ,  C08L101/16

    Abstract: The formation of a cream and gel is described using a biopolymer, such as a polyhydroxyalkanoate (PHA), a polylactide (PLA), a polylactideglycolide (PLGA) and a polyglycoside (PGA), or a derivative thereof, in a latex form with the addition of a binder, which is generally an amphiphilic chemical entity. An hydrophobic domain of the amphiphilic chemical entity interacts with at least one biopolymer forming a water soluble complex, while the hydrophilic domain of the amphiphilic chemical entity maintains the soluble complex in suspension in an aqueous solution, which after proper heating becomes a gel or a cream. As a result, a versatile gel or cream is created with different compositions and textures that are obtained based on the nature of the binder used and the ratio of biopolymers and binder(s).

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