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公开(公告)号：EP3175247B1
公开(公告)日：2020-08-19
申请号：EP15826849.0
申请日：2015-07-28
Applicant: Douglas Scientific, LLC
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公开(公告)号：EP3274708A1
公开(公告)日：2018-01-31
申请号：EP16769783.8
申请日：2016-03-25
Applicant: Douglas Scientific, LLC
Inventor： MISCHE, Hans , PEXSA, Grant , BAUMGARTNER, Mark , HODGSON, Cory , BRISTOW, Andrew , STECKELBERG, John , PATTERSON, Jared
Abstract: A modular testing device includes a base unit and an expansion unit that communicates with the base unit. The expansion unit includes a housing, a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed, and an optical assembly positioned in the housing. The optical assembly is configured to amplify and detect a signal from the biological sample and reagent mixture. Data that is collected in the optical assembly is communicated to the base unit.
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公开(公告)号：EP3175247A1
公开(公告)日：2017-06-07
申请号：EP15826849.0
申请日：2015-07-28
Applicant: Douglas Scientific, LLC
Inventor： COOK, Darren Lynn , JOHNSON, Eric Guy , WESTAD, Nathan Luther , HAUG, Andrew Richard , KONYNENBELT, James Henry , MAASJO, Grant, Edward , PATTERSON, Jared, Whittier , URKE, Brent Conrad , ZITZMANN, Ryan John , SMITH, Chad Steven
IPC: G01N35/02
Abstract: An instrument for processing a biological sample includes a chassis. Connected to the chassis is a tape path along which a tape with a matrix of wells can be automatically advanced through the instrument, a dispensing assembly for dispensing the biological sample and a reagent into the matrix of wells of the tape to form a biological sample and reagent mixture, a sealing assembly for sealing the biological sample and reagent mixture in the tape, and an amplification and detection assembly for detecting a signal from the biological sample and reagent mixture in the matrix of wells in the tape.
Abstract translation: 用于处理生物样品的仪器包括底盘。 连接到底盘的是磁带路径，带有矩阵阵列的磁带可以通过仪器自动前进，用于将生物样品和试剂分配到带的孔的基质中的分配组件以形成生物样品， 试剂混合物，用于密封带中的生物样品和试剂混合物的密封组件，以及扩增和检测组件，用于检测来自带中的孔中的生物样品和试剂混合物的信号。
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公开(公告)号：EP2943580A1
公开(公告)日：2015-11-18
申请号：EP14737813.7
申请日：2014-01-13
Applicant: Douglas Scientific
Inventor： WHALEN, Mark , GERVAIS, Charles , SANBORN, Anthony , HAUG, Andrew , COOK, Darren , RAI, Satish , MISCHE, Hans A. , JUDICE, Stephen A. , SHAFFER, Daniel J.
CPC classification number: B01J19/0046 , B01J2219/00313 , B01J2219/00351 , B01J2219/00495 , B01J2219/00585 , B01J2219/00722 , B01L7/00 , B01L2200/142 , B01L2300/0812 , B01L2300/1822 , B01L2300/1894 , C12Q1/6846 , G01N21/6456 , G01N35/00009 , G01N2035/00356 , G01N2035/0403 , G01N2035/1034
Abstract: A method for processing a biological material sample includes dispensing a sample into wells of an array tape from a sample plate, dispensing a reagent into the wells of the array tape from a reagent plate, and sealing the sample and the reagent in the array tape. The method further includes cooling the array tape and detecting biological material in the wells of the array tape.
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公开(公告)号：EP2991767A1
公开(公告)日：2016-03-09
申请号：EP14791217.4
申请日：2014-05-01
Applicant: Douglas Scientific, LLC
Inventor： SMITH, Chad Steven , HENDRICKX, Jacob , MISCHE, Hans A.
CPC classification number: B01L99/00 , B01L3/0275 , B01L2400/049 , B08B9/0323 , G01N35/1004
Abstract: A method of washing an array of pipette tips (94) with residual biological material includes lowering the array of pipette tips (94) into a wash basin (20) that includes an array of flush ports (22). A vacuum is generated such that the residual biological material in the array of pipette tips (94) is evacuated through the array of flush ports (22). A wash cycle is performed that includes raising the array of pipette tips (94) from the wash basin (20), filling the wash basin (20) with a primary wash fluid, lowering the array of pipette tips (94) into the wash basin (20), running a pipette tip cleansing cycle, and generating a vacuum such that the primary wash fluid in the array of pipette tips (94) and the wash basin (20) is evacuated through the array of flush ports (22).
Abstract translation: 用剩余生物材料清洗移液管尖端（94）阵列的方法包括将移液管尖端（94）阵列降低到包括一排冲洗端口（22）的清洗盆（20）中。 产生真空，使得移液管尖端（94）阵列中的残余生物材料通过冲洗端口阵列（22）被抽空。 执行洗涤循环，该循环包括从洗手盆（20）升起移液管吸头（94）阵列，用主洗涤液填充洗手盆（20），将移液管吸头（94）阵列降低到洗手盆 （20），运行移液管尖端清洁循环，并产生真空，使得移液管尖端（94）和洗手盆（20）的阵列中的主要清洗流体通过冲洗端口阵列（22）被抽空。
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Patent Agency Ranking
公开(公告)号：EP2970851A2
公开(公告)日：2016-01-20
申请号：EP14765559.1
申请日：2014-03-14
Applicant: Douglas Scientific, LLC
Inventor： MISCHE, Hans, Alois , COOK, Darren, Lynn
CPC classification number: G01N35/021 , B01L3/505 , B01L3/50851 , B01L2200/12 , B32B38/04 , B32B38/06 , B32B2535/00 , G01N35/00009 , G01N35/04 , G01N35/1002 , G01N2035/023 , G01N2035/0437
Abstract: A system for processing and analyzing a sample includes a belt with wells that proceeds through the system, a dispensing station that dispenses the sample and reagents into the wells of the belt, and a detection station that detects an analyte in the wells of the belt. The system further includes a wash and decontamination station for decontaminating the wells of the belt.
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公开(公告)号：EP2972408B1
公开(公告)日：2019-04-17
申请号：EP14762494.4
申请日：2014-03-14
Applicant: Douglas Scientific, LLC
Inventor： SCHOENECK, Richard J. , WAGNER, Paul H.
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公开(公告)号：EP3302017A1
公开(公告)日：2018-04-11
申请号：EP16800730.0
申请日：2016-05-26
Applicant: Douglas Scientific, LLC
Inventor： HENDRICKX, Jacob, P. , SMITH, Chad, S. , MISCHE, Hans, A. , BOTZET, Michael
CPC classification number: G01N1/286 , B01D15/00 , B02C18/10 , B02C18/16 , B02C23/16 , B02C2023/165 , G01N1/38 , G01N1/4077 , G01N2001/2866 , G01N2001/4088
Abstract: A seed grinder includes a housing that is configured to contain seeds and a buffer solution, a grinding mechanism that is positionable in the housing to grind the seeds in the housing, and a dispensing mechanism attached to the housing and configured to dispense the ground seeds and the buffer solution from the housing into a sample holder.
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公开(公告)号：EP2948466A1
公开(公告)日：2015-12-02
申请号：EP14742763.7
申请日：2014-01-23
Applicant: Douglas Scientific, LLC
Inventor： MISCHE, Hans
CPC classification number: C12Q1/6806 , B01L3/0255 , C07H1/06 , C07H1/08 , C07H21/00 , G01N1/405
Abstract: An apparatus for isolating nucleic acids includes an elongated body. The elongated body includes a silica surface positioned and configured to bind the nucleic acids when the elongated body is dipped into a biological material sample.
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公开(公告)号：EP3709026A1
公开(公告)日：2020-09-16
申请号：EP20173320.1
申请日：2015-07-28
Applicant: Douglas Scientific, LLC
Inventor： COOK, Darren Lynn , JOHNSON, Eric Guy , WESTAD, Nathan Luther , HAUG, Andrew Richard , KONYNENBELT, James Henry , MAASJO, Grant Edward , PATTERSON, Jared Whittier , URKE, Brent Conrad , ZITZMANN, Ryan John , SMITH, Chad Steven
Abstract: A dispensing assembly comprising:
a gantry with an x-axis track and a y-axis track, the y-axis track of the gantry configured to move along the x-axis track of the gantry;
a dispensing head attached to the y-axis track of the gantry below the y-axis track of the gantry, the dispensing head comprising:
a contact dispensing unit; and
a non-contact dispensing unit with a jet tip for dispensing a liquid;
a dispensing enclosure attached to the y-axis track of the gantry on top of the y-axis track of the gantry, the dispensing enclosure having a pressure reservoir; and
a tube connecting the jet tip of the non-contact dispensing unit to the pressure reservoir of the dispensing enclosure;
wherein the contact dispensing unit is attached to the y-axis track of the gantry with a first z-axis track; and
wherein the non-contact dispensing unit is attached to the contact dispensing unit with a second z-axis track.
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