公开(公告)号：US20100209313A1

公开(公告)日：2010-08-19

申请号：US12754195

申请日：2010-04-05

Applicant: Kenneth A. Davis ,  James J. Shelton

Inventor： Kenneth A. Davis ,  James J. Shelton

IPC: B01J19/08 ,  C01B13/11

CPC classification number: C02F9/005 ,  B67D2210/00013 ,  B67D2210/00023 ,  C02F1/685 ,  C02F1/78 ,  C02F2201/782 ,  C02F2209/005 ,  C02F2209/40

Abstract: A method and apparatus for providing sanitized water in a cabinet and spigot type bottled water dispenser features an ozone generating system to generate ozone for sanitizing the water. Ozone is generated and collected within an ozone generator housing. A blower transmits air to the ozone generator housing. The air carries the ozone that is generated through a flow line to an air diffuser that is positioned upstream of the spigot (or spigots) used to dispense water. In one embodiment, a valve that is activated on the spigot to dispense water also activates the blower and ozone generator. In other embodiments, a flow sensor activates the ozone generator and blower. Various spigot and flow sensor arrangements are disclosed as a part of the overall apparatus and method.

Abstract translation: 一种用于在橱柜和套管式瓶装饮水机中提供消毒水的方法和设备具有臭氧发生系统以产生用于消毒水的臭氧。 臭氧产生并收集在臭氧发生器壳体内。 鼓风机将空气传送到臭氧发生器壳体。 空气将通过流动管线产生的臭氧携带到位于用于分配水的插口（或插口）上游的空气扩散器。 在一个实施例中，在套管上启动以分配水的阀也激活鼓风机和臭氧发生器。 在其他实施例中，流量传感器激活臭氧发生器和鼓风机。 公开了各种插口和流量传感器装置作为整体装置和方法的一部分。

公开(公告)号：US07258803B2

公开(公告)日：2007-08-21

申请号：US11535754

申请日：2006-09-27

Applicant: Kenneth A. Davis

Inventor： Kenneth A. Davis

IPC: C02F1/78

CPC classification number: B67D3/0009 ,  B67D3/0029 ,  B67D3/0077 ,  B67D2210/00013 ,  C02F1/78 ,  C02F2201/782 ,  C02F2201/784 ,  C02F2209/005 ,  C02F2307/10

Abstract: An apparatus for a programmable self sanitizing water dispenser apparatus with a digital computer as well as a programmable method for generating ozone for cleaning the reservoir and the water contained within it.

Abstract translation: 一种用于具有数字计算机的可编程自清洁饮水机装置的装置以及用于产生用于清洁储存器的臭氧的可编程方法以及其中容纳的水。

公开(公告)号：US07114637B2

公开(公告)日：2006-10-03

申请号：US11109913

申请日：2005-04-20

Applicant: Kenneth A. Davis

Inventor： Kenneth A. Davis

IPC: B67D5/62

CPC classification number: C02F1/78 ,  B67D3/0009 ,  B67D3/0029 ,  B67D2210/00013 ,  C02F2209/005

Abstract: An apparatus for a programmable self sanitizing water dispenser apparatus with a digital computer as well as a programmable method for generating ozone for cleaning the reservoir and the water contained within it.

Abstract translation: 一种用于具有数字计算机的可编程自清洁饮水机装置的装置以及用于产生用于清洁储存器的臭氧的可编程方法以及其中容纳的水。

公开(公告)号：US06951727B2

公开(公告)日：2005-10-04

申请号：US10080868

申请日：2002-02-22

Applicant: Kenneth A. Davis

Inventor： Kenneth A. Davis

IPC: G01N33/53 ,  C07K16/28 ,  G01N33/531 ,  G01N33/533 ,  G01N33/536 ,  G01N33/569

CPC classification number: G01N33/56977 ,  C07K16/2896 ,  G01N33/56972 ,  G01N2333/70539 ,  G01N2333/70553 ,  Y10S435/961 ,  Y10S435/962 ,  Y10S435/975 ,  Y10S436/80 ,  Y10S436/808 ,  Y10S436/826

Abstract: Improved methods, reagents, and kits for quantitation of HLA-DR and/or CD11b expression on peripheral blood cells are presented. Inclusion of a lysosomotropic amine, such as chloroquine, during staining stabilizes HLA-DR and CD11b expression. Use of a novel anti-CD14 conjugate, anti-CD14-PerCP/CY5.5, permits the ready discrimination of monocytes. The improved methods, reagents, and kits may be used to assess immune competence, and to direct and monitor immunostimulatory therapies in septic patients exhibiting monocyte deactivation.

Abstract translation: 提出了用于定量外周血细胞上HLA-DR和/或CD11b表达的改进的方法，试剂和试剂盒。 在染色期间包含溶酶体胺，如氯喹，稳定了HLA-DR和CD11b的表达。 使用抗CD14结合物，抗CD14-PerCP / CY5.5，可以准确鉴别单核细胞。 可以使用改进的方法，试剂和试剂盒来评估免疫能力，并且指导和监测显示单核细胞失活的脓毒症患者的免疫刺激疗法。

公开(公告)号：US06372445B1

公开(公告)日：2002-04-16

申请号：US09521452

申请日：2000-03-07

Applicant: Kenneth A. Davis ,  Barnaby Abrams ,  James A. Bishop

Inventor： Kenneth A. Davis ,  Barnaby Abrams ,  James A. Bishop

IPC: G01N3353

CPC classification number: G01N33/58 ,  G01N33/532 ,  G01N33/533 ,  Y10S436/80

Abstract: The inventors herein disclose new heterobifunctional chromophores that are capable of coupling with two distinct moieties. One moiety may be either a signal-enhancing agent or a blocking agent. The second moiety may be one member of a specific binding pair. The invention is based in part on the surprising result that when a chromophore is used as a “cross-linker” between a signal-enhancing agent and a member of a binding pair (essentially being buried between the two), the signal of the chromophore is not quenched. This arrangement, wherein the chromophore acts simultaneously as a cross-linker and a detectable compound, provides significant advantages over previously known compounds since the chromophore is sterically hindered from interacting non-specifically with substances present in the test systems. Moreover, the chromophore can be used as a cross-linker with little or no loss of detectable signal.

Abstract translation: 本发明人在此公开了能够与两个不同部分偶联的新的异双功能发色团。 一个部分可以是信号增强剂或封闭剂。 第二部分可以是特异性结合对的一个成员。 本发明部分基于令人惊奇的结果，当发色团用作信号增强剂与结合对（基本上被埋在两者之间）的成员之间的“交联剂”时，发色团的信号 没有淬火。 这种布置，其中发色团作为交联剂和可检测化合物同时作用，提供了优于先前已知化合物的显着优点，因为发色团在空间上阻碍了非特异性地与测试系统中存在的物质相互作用。 此外，发色团可以用作交联剂，几乎没有或没有可检测信号的损失。

公开(公告)号：US5620842A

公开(公告)日：1997-04-15

申请号：US413045

申请日：1995-03-29

Applicant: Kenneth A. Davis ,  James E. Bishop

Inventor： Kenneth A. Davis ,  James E. Bishop

IPC: G01N15/10 ,  G01N15/14 ,  G01N33/58 ,  G01N33/96 ,  G01N31/00

CPC classification number: G01N15/1012 ,  G01N15/14 ,  G01N33/585 ,  G01N33/96 ,  Y10S435/967 ,  Y10S436/80 ,  Y10T436/101666

Abstract: A rapid, simple method for preparing beads for calibrating flow cytometers which contain a known number of fluorophores per bead is presented. Briefly, the invention utilizes beads coated with a stable complex of a fluorophore and an enzyme. the enzymatic activity of a known number of beads gives an accurate measure of fluorophore density on those beads.

Abstract translation: 提出了一种快速，简单的制备珠粒的方法，用于校准每个珠粒含有已知数量的荧光团的流式细胞仪。 简言之，本发明利用涂覆有荧光团和酶的稳定复合物的珠粒。 已知数量的珠的酶活性给出了这些珠上的荧光团密度的精确测量。

公开(公告)号：US08500993B2

公开(公告)日：2013-08-06

申请号：US12681342

申请日：2008-10-02

Applicant: Kenneth A. Davis

Inventor： Kenneth A. Davis

IPC: C02F1/78

CPC classification number: C02F1/78 ,  B67D3/0009 ,  B67D3/0032 ,  B67D3/0038 ,  B67D3/0074 ,  B67D3/0077 ,  B67D3/0083 ,  B67D2210/00007 ,  B67D2210/0001 ,  B67D2210/00013 ,  B67D2210/00023 ,  C02F1/003 ,  C02F1/008 ,  C02F1/50 ,  C02F2201/782 ,  C02F2201/784 ,  C02F2209/005 ,  C02F2209/235 ,  C02F2209/42 ,  C02F2209/44 ,  C02F2303/04 ,  C02F2307/10 ,  F25B49/00 ,  F25D11/00 ,  F25D23/12 ,  F25D31/002 ,  Y10S261/42

Abstract: An apparatus for a programmable self sanitizing water dispenser apparatus with a digital controller as well as a programmable method for generating ozone for cleaning the reservoir and the water contained within it. The apparatus includes an anti-spill receiver that houses the controller and that can contain a ozone generator.

公开(公告)号：US08007666B1

公开(公告)日：2011-08-30

申请号：US12126545

申请日：2008-05-23

Applicant: Kenneth A. Davis ,  James Jackson Shelton

Inventor： Kenneth A. Davis ,  James Jackson Shelton

IPC: C02F1/78

CPC classification number: C02F1/50 ,  B67D3/0035 ,  B67D3/0038 ,  B67D2210/00002 ,  B67D2210/00013 ,  C02F1/78 ,  C02F2201/78 ,  Y10S261/42

Abstract: A method and apparatus of sanitizing drinking water to be dispensed from a water dispenser having a reservoir includes the steps of providing the ozone gas generator that generates an ozone gas stream, transmitting the ozone gas stream from the generator to the water dispenser reservoir, mechanically breaking up the ozone gas stream inside the reservoir to produce ozone gas bubbles, and using the ozone gas bubbles to disinfect water in the reservoir. The ozone gas stream can be mechanically broken up using a pump such as, for example, an impeller type pump.

Abstract translation: 从具有储存器的饮水机中分配饮用水的方法和装置包括以下步骤：提供产生臭氧气流的臭氧气体发生器，将来自发生器的臭氧气体流传递到水分配器储存器，机械破裂 使储存器内的臭氧气流产生臭氧气泡，并利用臭氧气泡对储层中的水进行消毒。 可以使用诸如叶轮式泵的泵机械地分解臭氧气体流。

公开(公告)号：US07748233B2

公开(公告)日：2010-07-06

申请号：US11457365

申请日：2006-07-13

Applicant: Kenneth A. Davis ,  James J. Shelton

Inventor： Kenneth A. Davis ,  James J. Shelton

IPC: F25D3/00 ,  B67D7/76

CPC classification number: C02F1/78 ,  B01F3/0412 ,  B01F3/04269 ,  B01F2003/04191 ,  B01F2003/04326 ,  B01F2003/04361 ,  B67D1/07 ,  B67D2210/00013 ,  B67D2210/00023 ,  C01B13/10 ,  C01B13/11 ,  C02F1/685 ,  C02F9/005 ,  C02F2201/782 ,  C02F2201/784 ,  C02F2209/005 ,  C02F2209/40

Abstract: A method and apparatus for sanitizing a water dispenser that dispenses water for human consumption is disclosed. The dispenser can be in the form of any dispenser that dispenses water for human consumption employing a reservoir that dispenses water through one or more spigots. Water in the reservoir is sanitized with an air/ozone gas mixture that is transmitted to a porous polymeric diffuser having a central bore and a porous wall. The porosity of the porous wall defines bubble size.

Abstract translation: 公开了一种用于消毒水分配器以消耗人类消耗的方法和装置。 分配器可以是任何分配器的形式，其分配用于人类消费的水，其使用通过一个或多个插管分配水的储存器。 储存器中的水被空气/臭氧气体混合物消毒，该混合物被传送到具有中心孔和多孔壁的多孔聚合物扩散器。 多孔壁的孔隙度限定了气泡尺寸。

公开(公告)号：US07422684B1

公开(公告)日：2008-09-09

申请号：US10967812

申请日：2004-10-18

Applicant: Kenneth A. Davis ,  James Jackson Shelton

Inventor： Kenneth A. Davis ,  James Jackson Shelton

IPC: C02F1/78

CPC classification number: C02F1/50 ,  B67D3/0035 ,  B67D3/0038 ,  B67D2210/00002 ,  B67D2210/00013 ,  C02F1/78 ,  C02F2201/78 ,  Y10S261/42

Abstract: A method and apparatus of sanitizing drinking water to be dispensed from a water dispenser having a reservoir includes the steps of providing the ozone gas generator that generates an ozone gas stream, transmitting the ozone gas stream from the generator to the water dispenser reservoir, mechanically breaking up the ozone gas stream inside the reservoir to produce ozone gas bubbles, and using the ozone gas bubbles to disinfect water in the reservoir. The ozone gas stream can be mechanically broken up using a pump such as, for example, an impeller type pump.

Abstract translation: 从具有储存器的饮水机中分配饮用水的方法和装置包括以下步骤：提供产生臭氧气流的臭氧气体发生器，将来自发生器的臭氧气体流传递到水分配器储存器，机械破裂 使储存器内的臭氧气流产生臭氧气泡，并利用臭氧气泡对储层中的水进行消毒。 可以使用诸如叶轮式泵的泵机械地分解臭氧气体流。