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    APPARATUS FOR VISUALIZING AND ANALYZING GENE EXPRESSION PATTERNS USING GENE ONTOLOGY TREE AND METHOD THEREOF
    12.
    发明申请
    APPARATUS FOR VISUALIZING AND ANALYZING GENE EXPRESSION PATTERNS USING GENE ONTOLOGY TREE AND METHOD THEREOF 审中-公开
    用于使用基因本体树观察和分析基因表达模式的装置及其方法

    公开(公告)号：WO2010018882A1

    公开(公告)日：2010-02-18

    申请号：PCT/KR2008/004735

    申请日：2008-08-14

    Applicant: KOREA BASIC SCIENCE INSTITUTE ,  KWON, Kyung-Hoon ,  PARK, Gun Wook ,  LEE, Jeong Hwa ,  YOO, Jong Shin

    Inventor： KWON, Kyung-Hoon ,  PARK, Gun Wook ,  LEE, Jeong Hwa ,  YOO, Jong Shin

    IPC: G06F17/30 ,  C12Q1/68

    CPC classification number: G06F19/28 ,  G06F19/20 ,  G06F19/26

    Abstract: The present invention relates to an apparatus for visualizing or analyzing gene expression patterns of a biological sample using gene ontology tree and a method of the same, more precisely, an apparatus for visualizing or analyzing gene expression patterns which are regarded as biologically important using gene ontology tree by calculating complexity and a method of the same. This apparatus of the present invention is useful for comparing gene expression patterns in different biological samples using data produced by the said apparatus and the method of the present invention. According to the present invention, gene expression patterns in relation to molecular functions, biological processes or cellular components can be analyzed by investigating protein or RNA expression in biological samples. So, the apparatus and the method of the present invention can be effectively used for analysis of biologically important aspects such as functional changes, evolutionary stages or developmental stages of each biological sample.

    Abstract translation: 本发明涉及使用基因本体树来观察或分析生物样品的基因表达模式的装置及其方法，更确切地说，涉及用于使用基因本体论被视为生物学重要性的基因表达模式进行可视化或分析的装置 树的计算复杂度和方法相同。 本发明的该装置可用于使用由所述装置产生的数据和本发明的方法来比较不同生物样品中的基因表达模式。 根据本发明，可以通过研究生物样品中的蛋白质或RNA表达来分析与分子功能，生物过程或细胞成分有关的基因表达模式。 因此，本发明的装置和方法可以有效地用于生物学重要方面的分析，例如每个生物样品的功能变化，进化阶段或发育阶段。

    AUTOMATIC CONSTANT PRESSURE POLISHING APPARATUS FOR IMPROVING SURFACE ACCURACY OF LENS
    14.
    发明申请
    AUTOMATIC CONSTANT PRESSURE POLISHING APPARATUS FOR IMPROVING SURFACE ACCURACY OF LENS 审中-公开
    自动恒定压力抛光装置，用于提高镜头表面精度

    公开(公告)号：WO2008060091A1

    公开(公告)日：2008-05-22

    申请号：PCT/KR2007/005704

    申请日：2007-11-14

    Applicant: KOREA BASIC SCIENCE INSTITUTE ,  GREEN OPTICS CO., LTD. ,  KIM, Geonhee ,  YANG, Sunchoel ,  KIM, Dongkyun ,  KIM, Youngjoo ,  PARK, Hakjoo

    Inventor： KIM, Geonhee ,  YANG, Sunchoel ,  KIM, Dongkyun ,  KIM, Youngjoo ,  PARK, Hakjoo

    IPC: B24B13/00

    CPC classification number: B24B13/01 ,  B24B41/002 ,  B24B49/16

    Abstract: Disclosed is an automatic constant pressure polishing apparatus. The automatic constant pressure polishing apparatus comprises a housing having a hollow section therein, a rubber pad installed in the housing and having superior expansion and contraction characteristics, a pressure fixture having a male screw section, which is formed on an outer peripheral surface thereof in order to press and fix the rubber pad, and a central hole formed at a central portion thereof, a slider screw-coupled into the housing to adjust pressure in the housing according to a rotational degree of the rotating shaft, and a polishing pad installed at a front end portion of the housing.

    Abstract translation: 公开了一种自动恒压抛光装置。 所述自动恒压抛光装置包括其中具有中空部分的壳体，安装在所述壳体中并且具有优异的膨胀和收缩特性的橡胶垫，具有阳螺纹部分的压力夹具，其按顺序形成在其外周表面上 按压和固定橡胶垫，以及形成在其中心部分的中心孔，螺丝连接到壳体中的滑块，以根据旋转轴的转动程度来调节壳体中的压力;以及抛光垫，其安装在 外壳的前端部分。

    A METHOD FOR RECONSTRUCTING PROTEIN DATABASE AND A METHOD FOR IDENTIFYING PROTEINS BY USING THE SAME METHOD
    15.
    发明申请
    A METHOD FOR RECONSTRUCTING PROTEIN DATABASE AND A METHOD FOR IDENTIFYING PROTEINS BY USING THE SAME METHOD 审中-公开
    重组蛋白数据库的方法和使用相同方法识别蛋白质的方法

    公开(公告)号：WO2008007821A1

    公开(公告)日：2008-01-17

    申请号：PCT/KR2006/003261

    申请日：2006-08-18

    Applicant: KOREA BASIC SCIENCE INSTITUTE ,  KWON, Kyung-Hoon ,  YOO, Jong Shin

    Inventor： KWON, Kyung-Hoon ,  YOO, Jong Shin

    IPC: G06F17/30

    CPC classification number: G06F19/28 ,  G06F19/18 ,  G06F19/22

    Abstract: The present invention relates to a method for reconstructing protein database for identifying a protein and a method for screening a protein using the same, more precisely a method for reconstructing protein database comprising the steps of i) Grouping proteins having a required homology by using the clustering software from the primary database which minimizes the overlapping of proteins and then recording sequence information of each protein group on a recording system of a computer; and ii) Designating a representative protein in each protein group and then constructing the representative protein database composed of the representative proteins, followed by recording the results containing sequence information on a recording system of a computer, and a method for identifying a protein using the same. The method for reconstructing protein database and the method for identifying the protein of the invention are very useful for the investigation of endogenous proteins and their functions and interactions, and are further effectively used for the development of diagnostic and therapeutic agents for various diseases.

    Abstract translation: 本发明涉及一种用于重建用于鉴定蛋白质的蛋白质数据库的方法和使用该蛋白质筛选蛋白质的方法，更准确地说，一种重建蛋白质数据库的方法，包括以下步骤：i）通过使用聚类分组具有所需同源性的蛋白质 来自主数据库的软件，其最小化蛋白质的重叠，然后在计算机的记录系统上记录每个蛋白质组的序列信息; 和ii）指定每个蛋白质组中的代表性蛋白质，然后构建由代表性蛋白质组成的代表性蛋白质数据库，然后将含有序列信息的结果记录在计算机的记录系统上，以及用于鉴定使用其的蛋白质的方法 。 重组蛋白质数据库的方法和鉴定本发明蛋白质的方法对于内源蛋白质及其功能和相互作用的研究非常有用，并且进一步有效地用于各种疾病的诊断和治疗剂的开发。

    TANDEM FOURIER TRANSFORM ION CYCLOTRON RESONANCE MASS SPECTROMETER
    16.
    发明申请
    TANDEM FOURIER TRANSFORM ION CYCLOTRON RESONANCE MASS SPECTROMETER 审中-公开
    TANDEM FOURIER变换离子循环共振质谱仪

    公开(公告)号：WO2007091754A1

    公开(公告)日：2007-08-16

    申请号：PCT/KR2006/003618

    申请日：2006-09-12

    Applicant: KOREA BASIC SCIENCE INSTITUTE ,  KIM, Hyun Sik ,  CHOI, Myoung Choul ,  YOO, Jong Shin

    Inventor： KIM, Hyun Sik ,  CHOI, Myoung Choul ,  YOO, Jong Shin

    IPC: G01N27/62

    CPC classification number: G01N27/62

    Abstract: A tandem Fourier transform ion cyclotron resonance mass spectrometer is provided. In the mass spectrometer, the ions selected by a FT-ICR mass analyzer, which can perform an ion selection process and a mass measurement process with a time interval between the processes, are transmitted through an ion guide to a collision cell, which is located a predetermined distance from the FT-ICR mass analyzer, to split into fragment ions. The fragment ions are transmitted to the FT-ICR mass analyzer that measures the mass of the fragment ions. The fragment ions are generated in the collision cell 60 established separately from the FT- ICR mass analyzer 40 according to the mass spectrometer. Accordingly, It can solve various problems (e.g., the radius reduction of cyclotron motion of colliding ions, or the removal of periphery gas after generating the fragment ions) occurred in a tandem mass spectrometer using a conventional tandem-in-time mass analysis method. Also, a high resolution and hith sensitivity measurement can be achieved. Moreover, when a reagent gas instead of a collision gas in the collision cell is injected, the gas phase reaction of the selected ions and the reagent gas can be observed, and the mass of the ions generated in the gas phase reaction can be measured.

    Abstract translation: 提供了一种串联傅里叶变换离子回旋共振质谱仪。 在质谱仪中，可以进行离子选择处理的FT-ICR质量分析器选择的离子和在处理之间的时间间隔的质量测量过程通过离子导向器传输到位于 距离FT-ICR质量分析器预定的距离，以分裂为碎片离子。 碎片离子传输到测量碎片离子质量的FT-ICR质量分析仪。 在根据质谱仪与FT-ICR质量分析器40分开设置的碰撞单元60中产生碎片离子。 因此，可以使用常规的串联质量分析方法来解决在串联质谱仪中发生的各种问题（例如，产生碰撞离子的回旋加速器运动的半径减小或产生碎片离子之后的外围气体的去除）。 此外，可以实现高分辨率和高灵敏度测量。 此外，当注入反应气体代替碰撞气体中的碰撞气体时，可以观察到所选择的离子和反应气体的气相反应，并且可以测量在气相反应中产生的离子的质量。

    A DESIGN METHOD OF HIGH MAGNETIC FIELD SUPERCONDUCTING MAGNET
    17.
    发明申请
    A DESIGN METHOD OF HIGH MAGNETIC FIELD SUPERCONDUCTING MAGNET 审中-公开
    高磁场超导磁体的设计方法

    公开(公告)号：WO2006065027A1

    公开(公告)日：2006-06-22

    申请号：PCT/KR2005/004030

    申请日：2005-11-29

    Applicant: KOREA BASIC SCIENCE INSTITUTE ,  LEE, Byoung-Seob ,  KIM, Dong-Lak ,  KIM, Hyun-Sik ,  YOO, Jong-Shin

    Inventor： LEE, Byoung-Seob ,  KIM, Dong-Lak ,  KIM, Hyun-Sik ,  YOO, Jong-Shin

    IPC: H01F6/00

    CPC classification number: G01R33/3815

    Abstract: Disclosed is a method for designing a superconducting magnet for generating high magnetic fields with high uniformity for controlling a stray field to be within an allowable range and acquiring structural and magnetic stability by optimizing the arrangement of positions and shapes of coils configuring the superconducting magnet. Volumes of a main coil and a shielding coil are set to be variables, and the critical value of a wires related on the current and magnetic field, the heat transfer depth, and the quench strain are defined to be restriction conditions so that linear programming is applied to determine an initial shape of the shielding coil and division of the main coil based on the sum of total volumes, that is, an objective function. The initial shapes of the main coil and the shielding coil determined through the linear programming are revised and the shape of a shimming coil is determined by using non-linear programming based on the objective function.

    Abstract translation: 公开了一种设计用于产生高均匀性的高磁场的超导磁体的方法，用于通过优化构成超导磁体的线圈的位置和形状的布置来优化将杂散磁场控制在允许范围内并获得结构和磁稳定性。 主线圈和屏蔽线圈的体积被设置为变量，并且将与电流和磁场相关的导线的临界值，传热深度和骤冷应变定义为限制条件，使得线性规划是 用于确定屏蔽线圈的初始形状和基于总体积的总和即目标函数的主线圈的划分。 修改通过线性规划确定的主线圈和屏蔽线圈的初始形状，并且通过使用基于目标函数的非线性规划来确定匀场线圈的形状。

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