公开(公告)号：US3765255A

公开(公告)日：1973-10-16

申请号：US3765255D

申请日：1971-10-19

Applicant: MICROMEDIC SYSTEMS INC

Inventor： BAIN J

IPC: G01N35/04 ,  F16H27/02

CPC classification number: G01N35/04 ,  G01N2035/0413 ,  G01N2035/0475 ,  G01N2035/0484 ,  Y10T74/18848

Abstract: A load advancement mechanism characterized by a slip coupling driven by a constant speed gearmotor coacting with an initial torque imposed by a constant tension spring to advance a load engaging arm at a constant speed to a stop and further adapted to be retracted manually by pulling back on the arm.

Abstract translation: 一种负载提升机构，其特征在于由恒速减速电机驱动的滑动联轴器与由恒定拉力弹簧施加的初始扭矩共同作用，以将恒定速度的负载接合臂推进到止动件，并且还适于通过回拉手动地手动缩回 手臂。

公开(公告)号：US3753657A

公开(公告)日：1973-08-21

申请号：US3753657D

申请日：1971-06-11

Applicant: MICROMEDIC SYSTEMS INC

Inventor： DOWNING H ,  STURGIS B ,  LAWSON C

IPC: B01L9/06 ,  G01N35/10 ,  G01N21/00

CPC classification number: G01N35/10 ,  B01L9/06 ,  G01N35/1004

Abstract: An automatically controlled test tube transporter apparatus which advances a test tube rack containing two rows of receptacles for test tubes under a vertically movable aspirating and dispensing tip or nozzle which is adapted to move down into adjacent tubes and aspirate or discharge depending on the test to be performed. The tip is operationally in communication with a twin pipette metering and dispensing apparatus which includes a linearly adjustable eccentric mechanism which drives the pipette pistons with a motion of adjustable sinusoidal amplitude. The apparatus includes a solid state control circuit which includes a binary shift register. The pipettes may be adjusted to either work in parallel or alternating strokes. An automatic tip wiping mechanism, controlled by the operation of the tip, is provided to insure precision in the processing. The apparatus is adapted to be set for continuous operation or for individual test tube processing cycle operation. Empty racks can be advanced without engaging the tip and pump apparatus. The pipetting mechanism may be operated separately without the operation of the transporting mechanism. A malfunction and alarm logic circuit gives a warning in case of certain malfunctions and stops the apparatus.

Abstract translation: 一种自动控制的试管运送装置，其将包含两排用于试管的容纳管的试管架推进在可垂直移动的抽吸和分配尖端或喷嘴下方，该尖头或喷嘴适于根据试验向下移动到相邻管中并抽吸或排出 执行。 所述尖端与双移液管计量和分配装置可操作地连通，所述双移液管计量和分配装置包括可调节的正弦波幅度的运动驱动移液管活塞的可线性调节的偏心机构。 该装置包括一个包括二进制移位寄存器的固态控制电路。 移液管可以被调节成平行或交替的中风工作。 提供由尖端的操作控制的自动尖端擦拭机构，以确保处理的精度。 该装置适于设置用于连续操作或用于单独的试管处理循环操作。 空架可以先进，而不需要接头和泵装置。 移液机构可以分开操作而不需要运送机构的操作。 故障和报警逻辑电路在发生某些故障时发出警告，并停止设备。

公开(公告)号：US3751173A

公开(公告)日：1973-08-07

申请号：US3751173D

申请日：1972-08-24

Applicant: MICROMEDIC SYSTEMS INC

Inventor： SANZ M ,  REVILLET G

IPC: G01N21/05 ,  G01N1/10

CPC classification number: G01N21/05 ,  G01N2021/054

Abstract: The invention relates to optical cuvettes of the throughflow type and to the production thereof. The cuvette comprises a stratified block composed of at least three layers which together define a space constituting a doubly-bent continuous passage with a central elongated cavity communicating with two transverse branch-channels extending to the cuvette surface. An intermediate layer consists of a pair of transparent plates having oppositely arranged inner edges which are shaped in accordance with the path of said passage and are rounded off between the central cavity and the transverse channels, to provide streamline flow in the passage. Two lateral layers consist of plates which respectively close off the passage on either side thereof, between the shaped inner edges of said pair. The invention further provides a manufacturing method wherein two plate-edges are shaped in accordance with the profile of the doubly-bent passage and are oppositely arranged at a given distance to form an intermediate layer on to which two lateral plates are then mounted to close off the passage on either side thereof.

Abstract translation: 本发明涉及通流型的光学比色皿及其制造方法。 试管包括由至少三层组成的分层块，它们共同限定构成双重弯曲的连续通道的空间，中央细长腔与延伸到比色杯表面的两个横向分支通道连通。 中间层由一对具有相对布置的内边缘的透明板构成，所述内边缘根据所述通道的路径成形，并且在中心腔和横向通道之间被倒圆，以在通道中提供流线。 两个横向层由分别在其两侧的通道之间，在所述对的成形内边缘之间分离的板组成。 本发明还提供了一种制造方法，其中两个板边缘根据双弯曲通道的轮廓成形，并且以给定距离相对布置以形成中间层，然后安装两个侧板以关闭 其任一侧的通道。

公开(公告)号：US3692487A

公开(公告)日：1972-09-19

申请号：US3692487D

申请日：1970-03-17

Applicant: MICROMEDIC SYSTEMS INC

Inventor： SANZ MANUEL CLAUDE

IPC: G01N33/49 ,  G04F8/00 ,  G01N11/14 ,  G01N33/16 ,  G01N33/26

CPC classification number: G01N33/4905 ,  G04F8/006

Abstract: A TWO PIECE TUBULAR CAPSULE FOR CONDUCTING COAGULATION TESTS ON BLOOD AND OTHER LIQUIDS HAVING THREE SEPARATE CHAMBERS, THE FIRST TWO COMMUNICATING WITH EACH OTHER, DEFINED BY TWO FRANGILBE MEMBRANES AND A SOLID DISC. A SHAFT HAVING A RECESSED STIRRING END IS ATTACHED TO THE FIRST MEMBRANE AND COOPERATES WITH A STIRRING SLUG ATTACHED TO SAID SECOND MEMBRANE. THE SHAFT IS MOVED AXIALLY TO BREAK THE SECOND MEMBRANE AND MIX THE LIQUIDS IN EACH CHAMBER. THE SHAFT IS THEN ROTATED RELATIVE TO THE BODY OF THE CAPSULE TO STIR THE MIXED LIQUID TO DETERMINE THE COAGULATION TIME OF THE SAMPLE LIQUID BEING TESTED.

公开(公告)号：US3623475A

公开(公告)日：1971-11-30

申请号：US3623475D

申请日：1969-07-18

Applicant: MICROMEDIC SYSTEMS INC

Inventor： SANZ MANUEL ,  REVILLET GEORGES

IPC: A61B5/15 ,  A61B5/14

CPC classification number: A61B5/150977 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150175 ,  A61B5/150343 ,  A61B5/150412 ,  A61B5/150442 ,  A61B5/150748 ,  A61B5/15113 ,  A61B5/15117

Abstract: A tube for use in the automatic collection of a digital blood sample has its mouth fitted with a resilient detachable funnel member which can carry a capillary cannula and in which is held an absorbent annular plug through which pass and project two incisor lancets.

公开(公告)号：US3901600A

公开(公告)日：1975-08-26

申请号：US44353274

申请日：1974-02-19

Applicant: MICROMEDIC SYSTEMS INC

Inventor： JOHNSON JR EDGAR G ,  STONECYPHER THOMAS E ,  LAWSON CHARLES V

IPC: G01N21/31 ,  G01N21/27 ,  G06F7/62 ,  H03M1/00 ,  G01J3/42

CPC classification number: G01N21/272 ,  G06F7/62

Abstract: Enzyme concentration at a fixed temperature is measured in terms of change in absorbance per unit time over selected time intervals. The rate of change of the absorbence is electronically calculated from the output of a spectrophotometer. Two modes of operation are provided to accommodate either increasing or decreasing changes in absorbance.

公开(公告)号：US3865495A

公开(公告)日：1975-02-11

申请号：US36344473

申请日：1973-05-24

Applicant: MICROMEDIC SYSTEMS INC

Inventor： SANZ MANUEL C ,  REVILLET GEORGES ,  JOHNSON JR EDGAR G

IPC: G01N21/03 ,  G01N1/10

CPC classification number: G01N21/03

Abstract: The present invention is concerned with a spectrophotometer useful for determining light transmission of microsamples. It is particularly concerned with a spectrophotometer system using an improved microcuvette and extremely small optical elements for providing and acting upon the light beam that is used in determining the light-transmission characteristics of the sample. It is more particularly concerned with a double-cavity cuvette for receiving in one of the cavities of the cuvette a comparison or reference material and, in the other, the sample to be measured. Even more particularly it is concerned with a doublecavity micro-cuvette particularly adapted for utilizing a shifted-beam light system in which the beam is alternately refracted in different directions to direct it alternately through one cavity and then the other.

Abstract translation: 本发明涉及可用于确定微量样品的光透射的分光光度计。 特别涉及一种分光光度计系统，该分光光度计系统使用改进的微型显微镜和极小的光学元件来提供和作用于用于确定样品的光传输特性的光束。 更特别地涉及用于在比色皿的一个空腔中接收比较或参考物质的另外的双腔比色杯，另一方面是待测量的样品。 更具体地说，涉及一种特别适用于利用偏转光束光系统的双腔微量比色皿，其中光束在不同方向上被交替地折射以将其交替地引导通过一个空腔，然后另一个。

公开(公告)号：US3826621A

公开(公告)日：1974-07-30

申请号：US24891972

申请日：1972-05-01

Applicant: MICROMEDIC SYSTEMS INC

Inventor： JOHNSON E ,  CORNELISON J

IPC: G01N35/10 ,  G01N1/00 ,  G01N1/14

CPC classification number: G01N35/1095 ,  Y10T436/119163 ,  Y10T436/2575

Abstract: LIQUID IN SELECTED QUANTITIES IS TRANSFERRED THROUGH A CONDUIT FROM A CONTAINER TO THE OPERATIVE SECTION OF AN ANALYTICAL INSTRUMENT BY APPLYING GAS PRESSURE TO THE SURFACE OF THE LIQUID FOR A PREDETERMINED AMOUNT OF TIME. THE CHAMBER FOR COUPLING THE GAS PRESSURE TO THE SURFACE OF A LIQUID IS PROVIDED WITH A GAS BYPASS TO PREVENT SPRAYING OF THE LIQUID. THE GAS PRESSURE IS DIRECTED ONTO THE SURFACE OF THE CONDUIT TO REMOVE ANY LIQUID THAT REMAINS ON THE CONDUIT AFTER A SELECTED QUANTITY HAS BEEN TRANSFERRED TO THE OPERATIVE PART OF THE ANALYTICAL INSTRUMENT.

公开(公告)号：US3780912A

公开(公告)日：1973-12-25

申请号：US2728970

申请日：1970-08-19

Applicant: MICROMEDIC SYSTEMS INC

Inventor： SANZ M

IPC: G01N1/00 ,  G01N1/38 ,  G01F11/06

CPC classification number: G01N35/1097 ,  G01N2001/382

Abstract: A metering and dispensing apparatus with a pump having intake and discharge strokes coupled to a switching valve which cylindrically connects the pump in open communication with a first, then a second, port with an idling pause between the conditions. A mechanism converting rotary motion to sinusoidal reciprocating motion actuates the pump piston, the length of stroke of the piston being selectively adjustable within the motion conversion mechanism in accordance with an indicator indicative of the desired volume.

Abstract translation: 一种具有泵的计量和分配装置，其具有联接到切换阀的进气和排出冲程，所述切换阀使泵以与条件之间的空转暂停的开放式通信方式与第一，然后第二端口圆柱形连接。 将旋转运动转换为正弦往复运动的机构致动泵活塞，活塞的行程长度可根据指示所需体积的指示器在运动转换机构内选择性地调节。

公开(公告)号：US3706233A

公开(公告)日：1972-12-19

申请号：US3706233D

申请日：1970-08-19

Applicant: MICROMEDIC SYSTEMS INC

Inventor： SANZ MANUEL CLAUDE ,  WEBER RENE

IPC: F16H21/50 ,  F16H21/16

CPC classification number: F16H21/50 ,  Y10T74/18056

Abstract: A mechanism vehicle converts rotary motion to reciprocal linear or arcuate motion of variable amplitude consisting of a tubular housing having a rotary member therein with longitudinal slots for accomodating a slide piece. A block carrying an offset pivot bearing is mounted in said housing in spaced relation to said rotary member and a crank arm is positioned between said pivot and a lug which is in offset hinged relation to a slide positioned in said slots so that rotation of said crank arm generates a cone. A carrier bearing and assembly translates the rotation of said crank arm into reciprocal linear movement of a pair of slide blocks positioned in slots in said housing. A threaded adjustment member determines the spacing between said rotary member and said block carrying the pivot bearing so as to vary the stroke of the slide blocks in relation to the position of the carrier bearing on the cone generated by rotation of said crank arm.

Abstract translation: 机构车辆将旋转运动转换成具有可变幅度的往复线性或弓形运动，其包括具有旋转构件的管状壳体，其中具有用于容纳滑块的纵向狭槽。 承载偏移枢转轴承的块以与所述旋转构件隔开的关系安装在所述壳体中，并且曲柄臂位于所述枢轴和凸耳之间，所述凸耳与位于所述槽中的滑块偏置铰链，使得所述曲柄 手臂产生一个锥体。 载体轴承和组件将所述曲柄臂的旋转转换成位于所述壳体中的狭槽中的一对滑块的往复线性运动。 螺纹调节构件确定所述旋转构件和承载枢转轴承的所述块之间的间隔，以便相对于通过所述曲柄臂的旋转产生的锥体上的托架支承件的位置来改变滑块的行程。