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公开(公告)号:WO2008082439A3
公开(公告)日:2008-12-04
申请号:PCT/US2007018683
申请日:2007-08-24
Applicant: UNIV DUKE , MOODY MICHAEL A , HAYNES BARTON F
Inventor: MOODY MICHAEL A , HAYNES BARTON F
CPC classification number: G01N33/588 , B82Y5/00 , B82Y15/00 , B82Y30/00 , G01N33/56972 , G01N2333/16
Abstract: The present invention relates, in general, to nanoparticles and, in particular, to nanoparticles coated with, for example, peptides, proteins, and/or carbohydrates, and to methods of producing and using same. The invention further relates to kits comprising the coated nanoparticles.
Abstract translation: 本发明一般涉及纳米颗粒,特别涉及涂覆有例如肽,蛋白质和/或碳水化合物的纳米颗粒,以及制备和使用它们的方法。 本发明还涉及包含涂覆的纳米颗粒的试剂盒。
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公开(公告)号:WO2007112079A2
公开(公告)日:2007-10-04
申请号:PCT/US2007/007399
申请日:2007-03-26
Applicant: DUKE UNIVERSITY , HAYNES, Barton, F. , MOODY, Michael , VERKOZCY, Laurent , SULLENGER, Bruce, A. , LAZYER, Juliana
Inventor: HAYNES, Barton, F. , MOODY, Michael , VERKOZCY, Laurent , SULLENGER, Bruce, A. , LAZYER, Juliana
IPC: A61K39/42
CPC classification number: C07K16/1045 , A61K39/12 , A61K39/21 , A61K2039/545 , A61K2039/55561 , A61K2039/55566 , A61K2039/6018 , C07K2317/76 , C12N2740/16134
Abstract: The present invention relates, in general, to HIV and, in particular, to immunogens that present epitopes located in the membrane external proximal region (MPER) of HIV-I envelope gp41 in multivalent form and to methods of using same.
Abstract translation: 本发明一般涉及HIV,特别是涉及以多价形式存在位于HIV-1信封gp41的膜外近区(MPER)中的表位的免疫原和使用其的方法。
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公开(公告)号:WO2007112079A3
公开(公告)日:2007-12-21
申请号:PCT/US2007007399
申请日:2007-03-26
Applicant: UNIV DUKE , HAYNES BARTON F , MOODY MICHAEL , VERKOZCY LAURENT , SULLENGER BRUCE A , LAZYER JULIANA
Inventor: HAYNES BARTON F , MOODY MICHAEL , VERKOZCY LAURENT , SULLENGER BRUCE A , LAZYER JULIANA
IPC: A61K39/00
CPC classification number: C07K16/1045 , A61K39/12 , A61K39/21 , A61K2039/545 , A61K2039/55561 , A61K2039/55566 , A61K2039/6018 , C07K2317/76 , C12N2740/16134
Abstract: The present invention relates, in general, to HIV and, in particular, to immunogens that present epitopes located in the membrane external proximal region (MPER) of HIV-I envelope gp41 in multivalent form and to methods of using same.
Abstract translation: 本发明一般涉及HIV,特别涉及以多价形式存在于HIV-1包膜gp41的膜外部近侧区域(MPER)中的表位的免疫原及其使用方法。
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公开(公告)号:WO02075379A3
公开(公告)日:2003-02-27
申请号:PCT/GB0201239
申请日:2002-03-18
Applicant: BOOKHAM TECHNOLOGY PLC , MOODY MICHAEL , READ KEITH
Inventor: MOODY MICHAEL , READ KEITH
CPC classification number: H01S3/06754 , G02B6/4457 , H01S3/04 , H01S3/06704
Abstract: An optical component comprises a coil (13) of optical fibre having heating means comprising a heating element (14) located substantially within the coil. The heating element is annular and has similar dimensions to the coil. All radiating surfaces of the element are employed to heat the fibre to an elevated temperature. Control circuitry is provided to ensure that the fibre remains at an optimum temperature. This arrangement is especially suitable for incorporation in an optical amplifier (1).
Abstract translation: 光学部件包括具有加热装置的光纤线圈(13),该加热装置包括基本上位于线圈内的加热元件(14)。 加热元件是环形的并且具有与线圈相似的尺寸。 元件的所有辐射表面用于将纤维加热到升高的温度。 提供控制电路以确保光纤保持在最佳温度。 这种布置特别适用于结合在光放大器(1)中。
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公开(公告)号:WO02075866A3
公开(公告)日:2003-02-20
申请号:PCT/GB0201244
申请日:2002-03-18
Applicant: BOOKHAM TECHNOLOGY PLC , MOODY MICHAEL , READ KEITH
Inventor: MOODY MICHAEL , READ KEITH
CPC classification number: H01S3/06754 , G02B6/4457 , H01S3/042 , H01S3/06704 , H01S3/1301
Abstract: An active optical device comprising a first plate 1, which plate co-operates with a second plate 2, which second plate 2 is adapted to receive an optical fibre 30, wherein the second plate is further adapted to receive at least one PTC element 5, which PTC element is adapted to heat the optical component to a predetermined temperature. The use of a PTC element facilitates the design and manufacture of thin devices with a self-regulating heater.
Abstract translation: 一种有源光学装置,包括第一板1,该板与第二板2协作,第二板2适于接收光纤30,其中第二板还适于容纳至少一个PTC元件5, 该PTC元件适于将光学部件加热到预定温度。 使用PTC元件有助于设计和制造具有自调节加热器的薄装置。
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公开(公告)号:WO2010054407A1
公开(公告)日:2010-05-14
申请号:PCT/US2009/063934
申请日:2009-11-10
Applicant: WEATHERFORD/LAMB, INC. , XU, Wei Jake , ODELL, II, Albert C. , HARRALL, Simon J. , REDLINGER, Thomas M. , VREELAND, Christopher M. , ANTOINE, Andrew , BRUNNERT, David J. , LAIRD, Thomas , MOODY, Michael , TILTON, Frederick T.
Inventor: XU, Wei Jake , ODELL, II, Albert C. , HARRALL, Simon J. , REDLINGER, Thomas M. , VREELAND, Christopher M. , ANTOINE, Andrew , BRUNNERT, David J. , LAIRD, Thomas , MOODY, Michael , TILTON, Frederick T.
IPC: E21B10/32
CPC classification number: E21B10/32 , E21B10/322 , E21B10/327
Abstract: Embodiments of the present invention generally relate to extendable cutting tools for use in a wellbore. In one embodiment, a tool for use in a wellbore includes a tubular body having a bore therethrough, an opening through a wall thereof, and a connector at each longitudinal end thereof; and an arm. The arm is pivotally connected to a first piston and rotationally coupled to the body, is disposed in the opening in a retracted position, and is movable to an extended position where an outer surface of the arm extends outward past an outer surface of the body. The tool further includes the first piston. The first piston is disposed in the body bore, has a bore therethrough, and is operable to move the arm from the retracted position to the extended position in response to fluid pressure in the piston bore exceeding fluid pressure in the opening. The tool further includes a lock operable to retain the first piston in the retracted position; and a second piston operably coupled to the lock.
Abstract translation: 本发明的实施例一般涉及用于井眼的可延伸的切削工具。 在一个实施例中,用于井眼的工具包括具有穿过其中的孔的管状体,穿过其壁的开口,以及在其每个纵向端的连接器; 和一只手臂。 所述臂枢转地连接到第一活塞并且旋转地联接到所述主体,所述臂在缩回位置处设置在所述开口中,并且可移动到所述臂的外表面向外延伸穿过所述主体的外表面的延伸位置。 该工具还包括第一活塞。 第一活塞设置在身体孔中,具有穿过其中的孔,并且可操作以响应于活塞孔中的流体压力而将臂从缩回位置移动到延伸位置,超过开口中的流体压力。 该工具还包括可操作以将第一活塞保持在缩回位置的锁; 以及可操作地联接到所述锁的第二活塞。
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公开(公告)号:WO2002075379A2
公开(公告)日:2002-09-26
申请号:PCT/GB2002/001239
申请日:2002-03-18
Applicant: BOOKHAM TECHNOLOGY PLC , MOODY, Michael , READ, Keith
Inventor: MOODY, Michael , READ, Keith
IPC: G02B6/00
CPC classification number: H01S3/06754 , G02B6/4457 , H01S3/04 , H01S3/06704
Abstract: An optical component comprises a coil (13) of optical fibre having heating means comprising a heating element (14) located substantially within the coil. The heating element is annular and has similar dimensions to the coil. All radiating surfaces of the element are employed to heat the fibre to an elevated temperature. Control circuitry is provided to ensure that the fibre remains at an optimum temperature. This arrangement is especially suitable for incorporation in an optical amplifier (1).
Abstract translation: 光学部件包括具有加热装置的光纤线圈(13),该加热装置包括基本上位于线圈内的加热元件(14)。 加热元件是环形的并且具有与线圈相似的尺寸。 元件的所有辐射表面用于将纤维加热到升高的温度。 提供控制电路以确保光纤保持在最佳温度。 这种布置特别适用于结合在光放大器(1)中。
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