公开(公告)号：IL148826A

公开(公告)日：2010-12-30

申请号：IL14882602

申请日：2002-03-21

Applicant: STEWART DUNCAN ,  NORTHERN THERAPEUTICS INC ,  AN GO GEN INC

Inventor： STEWART DUNCAN

IPC: A61K35/36 ,  A61K35/28 ,  A61K35/33 ,  A61K38/18 ,  A61K48/00 ,  A61P9/12 ,  A61P11/00 ,  C07K14/52 ,  C12N5/10 ,  C12N15/09

公开(公告)号：AU2003294540A1

公开(公告)日：2004-07-22

申请号：AU2003294540

申请日：2003-12-24

Applicant: COURTMAN DAVID ,  NORTHERN THERAPEUTICS INC ,  STEWART DUNCAN J ,  BABAEI SAEID

Inventor： COURTMAN DAVID ,  STEWART DUNCAN J ,  BABAEI SAEID

IPC: A61K31/198 ,  A61K31/216 ,  A61K38/17 ,  A61K38/18 ,  A61K48/00 ,  C12N9/02

Abstract: Early onset of pulmonary disorders such as pulmonary hypertension are treated or prevented by administration of an apoptosis inhibitor or a survival factor. Early onset of such disorders may be diagnosed by assessing apoptosis in lung tissue.

公开(公告)号：CA2450643A1

公开(公告)日：2004-04-30

申请号：CA2450643

申请日：2003-12-24

Applicant: NORTHERN THERAPEUTICS INC

Inventor： COURTMAN DAVID ,  BABAEI SAEID ,  STEWART DUNCAN J

IPC: A61K31/198 ,  A61K31/216 ,  A61K38/17 ,  A61K38/18 ,  A61K48/00 ,  A61P11/00 ,  A61K45/06 ,  A61K35/12 ,  A61P9/12 ,  C12Q1/37 ,  G01N33/53 ,  A61K31/7088

Abstract: Early onset of pulmonary disorders such as pulmonary hypertension are treate d or prevented by administration of an apoptosis inhibitor or a survival factor. Early onset of such disorders may be diagnosed by assessing apoptosis in lung tissue.

公开(公告)号：EP1839667A3

公开(公告)日：2010-04-14

申请号：EP07009031.1

申请日：1999-09-23

Applicant: Northern Therapeutics Inc.

Inventor： Stewart, Duncan J.

IPC: A61K48/00 ,  A61K38/18 ,  A61K38/44 ,  A61P11/00

CPC classification number: A61K38/44 ,  A61K35/36 ,  A61K38/1866 ,  A61K48/00 ,  A61K48/0075 ,  C07K14/52 ,  C12Y114/13039

Abstract: Cell-based gene transfer is effected by administering transfected fibroblast cells, from dermal or other origins, containing an expressible transgene coding for an angiogenic factor or other therapeutic factor, into the pulmonary circulation of a patient, where the cells express and secrete expression products of the transgene to act locally at the site of expression, and in some cases to be conveyed by the patient's circulation to other body organs. The process is especially useful in treatment of pulmonary hypertension by means of expressed angiogenic factors.

公开(公告)号：EP1839667B1

公开(公告)日：2015-06-17

申请号：EP07009031.1

申请日：1999-09-23

Applicant: Northern Therapeutics Inc.

Inventor： Stewart, Duncan J.

IPC: A61K35/36 ,  A61K48/00 ,  A61K38/18 ,  A61P11/00 ,  C07K14/52 ,  A61K38/44

CPC classification number: A61K38/44 ,  A61K35/36 ,  A61K38/1866 ,  A61K48/00 ,  A61K48/0075 ,  C07K14/52 ,  C12Y114/13039

公开(公告)号：EP4392559A1

公开(公告)日：2024-07-03

申请号：EP22859731.6

申请日：2022-08-22

Applicant: Northern Therapeutics Inc.

Inventor： STEWART, Duncan ,  COURTMAN, David

IPC: C12N15/113 ,  A61K35/12 ,  A61K38/44 ,  A61K48/00 ,  A61P9/00 ,  A61P9/10 ,  C12N9/02 ,  C12N15/10 ,  C12N15/53 ,  C12N15/85

CPC classification number: A61P9/00 ,  A61P9/10 ,  C12N15/85 ,  C12N9/0075 ,  C12Y114/13039 ,  C12N2830/00820130101 ,  C12N2830/00220130101 ,  A61K48/005 ,  A61K48/0058 ,  C12N2830/1520130101