公开(公告)号：WO2004039999A3

公开(公告)日：2004-05-13

申请号：PCT/US2003/024982

申请日：2003-08-08

Applicant: SYNGENTA PARTICIPATIONS AG ,  STAM, Lynn ,  KAMDAR, Kim, Puloma ,  SPANA, Eric ,  BACHMANN, Jane

Inventor： STAM, Lynn ,  KAMDAR, Kim, Puloma ,  SPANA, Eric ,  BACHMANN, Jane

IPC: A61K38/00

Abstract: Nucleotide sequences are isolated from Drosophila melanogaster that code for proteins essential for viability. These proteins are useful for discovering new insecticides based on the essentiality of the nucleotide sequences for Drosophila viability. Further provided are recombinant proteins and methods for identifying inhibitors to these proteins. Protein inhibitors active in the methods disclosed herein are useful as insecticidal, ectoparasiticidal, antiparasitic, anthementhic and acaracidal agents.