아텔로콜라겐을 이용한 췌도세포 이식용 담체의 제조방법 그리고 이를 이용하여 제조된 인공췌장
    12.
    发明公开
    아텔로콜라겐을 이용한 췌도세포 이식용 담체의 제조방법 그리고 이를 이용하여 제조된 인공췌장 有权
    培养胰岛细胞的方法和制造使用甲基胆碱转运胰腺细胞的载体和用相同方法制造的人造胰蛋白酶

    公开(公告)号:KR1020130101204A

    公开(公告)日:2013-09-13

    申请号:KR1020120022152

    申请日:2012-03-05

    Abstract: PURPOSE: A manufacturing method of a carrier for the islet cell transplantation using atelocollagen, and an artificial pancreas manufactured using the same are provided to be able to efficiently incubate islet cells and provide a carrier for the islet cell transplantation with an excellent stability and an artificial pancreas by using cationized atelocollagen. CONSTITUTION: A manufacturing method of a carrier for the islet cell transplantation comprises the following steps: a cationized atelocollagen solution and an alginate solution are mixed; islet cells are mixed in the mixed solution of the cationized atelocollagen solution and the alginate solution; an islet cell complex, which is surrounded by the mixed solution of the cationized atelocollagen solution and the alginate solution and mixed with islet cells, is formed; an islet cell complex, which is surrounded by the mixed solution of the cationized atelocollagen solution and the alginate solution and mixed with islet cells, is deposited in a chelating agent to produce a cationized atelocollagen/alginate bead in which an islet cell is accommodated inside. [Reference numerals] (AA) Number of langerhans islet cells; (BB) 1 day; (CC) 3 week; (DD) 8 week

    Abstract translation: 目的:提供使用小胶质细胞的胰岛细胞移植的载体的制造方法和使用其制造的人造胰腺,以能够有效孵育胰岛细胞并提供具有优异的稳定性和人造的胰岛细胞移植的载体 胰腺通过使用阳离子化的atelocollagen。 构成:用于胰岛细胞移植的载体的制造方法包括以下步骤:将阳离子化的胶原凝胶溶液和藻酸盐溶液混合; 胰岛细胞在阳离子化的胶原蛋白溶液和藻酸盐溶液的混合溶液中混合; 形成由阳离子化的胶原凝胶溶液和藻酸盐溶液的混合溶液包围并与胰岛细胞混合的胰岛细胞复合体; 由阳离子化的胶原蛋白溶液和藻酸盐溶液的混合溶液包围并与胰岛细胞混合的胰岛细胞复合物沉积在螯合剂中以产生其中容纳胰岛细胞的阳离子化的胶原/藻酸盐珠粒。 (附图标记)(AA)朗格汉斯胰岛细胞数; (BB)1天; (CC)3周; (DD)8周

    아텔로콜라겐을 이용한 췌도세포의 배양방법
    14.
    发明公开
    아텔로콜라겐을 이용한 췌도세포의 배양방법 有权
    使用紫杉醇培养胰岛细胞的方法

    公开(公告)号:KR1020130101488A

    公开(公告)日:2013-09-13

    申请号:KR1020130099743

    申请日:2013-08-22

    Abstract: PURPOSE: A method for culturing islet cells using atelocollagen is provided to effectively culture islet cells using a cationized atelocollagen or crosslinked atelocollagen support which is acquired by ionizing high purity atelocollagen. CONSTITUTION: A method for culturing islet cells using atelocollagen comprises the steps of preparing a cationized atelocollagen solution; applying the cationized atelocollagen solution on a culture container and drying to form a cationized atelocollagen support; inoculating islet cells to the cationized atelocollagen solution; and culturing the inoculated islet cells in the cationized atelocollagen solution or on the cationized atelocollagen support. [Reference numerals] (AA) Number of islet cells; (BB) 1 day; (CC) 3 weeks; (DD) 8 weeks

    Abstract translation: 目的:提供使用小胶原蛋白培养胰岛细胞的方法,以有效培养胰岛细胞,使用通过离子化高纯度胶原蛋白获得的阳离子化的阿胶原或交联的阿胶原载体。 构成:使用阿胶囊培养胰岛细胞的方法包括制备阳离子化的胶原蛋白溶液的步骤; 将阳离子化的胶原凝胶溶液施加到培养容器上并干燥以形成阳离子化的胶原蛋白载体; 将胰岛细胞接种到阳离子化的胶原蛋白溶液中; 并在阳离子化的胶原蛋白溶液或阳离子化的胶原蛋白载体上培养接种的胰岛细胞。 (附图标记)(AA)胰岛细胞数; (BB)1天; (CC)3周; (DD)8周

Patent Agency Ranking