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公开(公告)号：KR101272738B1
公开(公告)日：2013-06-10
申请号：KR1020060092357
申请日：2006-09-22
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 구강용 과립의 제조방법 및 이 방법에 의해 제조된 과립을 함유하는 구강용 조성물에 관한 것으로, 더욱 상세하게는 구강질환의 예방 및 치료효과가 있는 식물 추출물 및 화합물을 유동층 코팅기(fluid bed coater)를 사용하여 구형태의 구강용 과립을 제조하고 이를 구강용 조성물에 첨가함으로써 구강질환의 예방 및 치료효과가 뛰어나고, 사용시 자극이 적고 안전하며, 구강용 유효성분의 안정성이 향상된 구강용 조성물에 관한 것이다.
구강용과립*유동층코팅기*구강용 조성물-
公开(公告)号：KR1020070102184A
公开(公告)日：2007-10-18
申请号：KR1020060034006
申请日：2006-04-14
Applicant: (주)아모레퍼시픽
Abstract: An oral composition is provided to improve antibacterial effects on harmful bacteria in oral cavity, thereby inhibiting plaque on the teeth and preventing oral disease and gingival ailments including gingivitis and periodontitis by adding the willow extract into a cationic sterilizer. An oral composition for preventing oral disease and gingival ailments comprises (i) 0.01-5 wt.% of a cationic sterilizer selected from cetyl pyridium chloride, hexal konium chloride, benzal konium chloride and chlorhexidine and (ii) 0.1-2 wt.% of the willow extract which is prepared by extracting willow branches in extraction solvent such as purified water and ethanol, and filtering, concentrating and drying the extract.
Abstract translation: 提供一种口腔用组合物以改善对口腔中有害细菌的抗菌作用，从而通过将柳叶提取物加入到阳离子灭菌器中，从而抑制牙齿上的斑块并防止口腔疾病和牙龈疾病，包括牙龈炎和牙周炎。 用于预防口腔疾病和牙龈疾病的口服组合物包括（i）0.01-5重量％的阳离子灭菌器，其选自氯化十六烷基吡啶，六氯化锍，苄基氯化铵和氯己定，和（ii）0.1-2重量％ 通过在提取溶剂如纯水和乙醇中提取柳枝来制备柳叶提取物，并过滤，浓缩和干燥提取物。
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公开(公告)号：KR1020070012907A
公开(公告)日：2007-01-30
申请号：KR1020050067140
申请日：2005-07-25
Applicant: (주)아모레퍼시픽
Abstract: A toothpaste composition for tooth whitening is provided to increase long-term storage by inhibiting degradation of peroxides and release of reactive oxygen species using a metal-free abrasive. The toothpaste composition for tooth whitening comprises peroxides and purified silica as an abrasive, wherein the peroxide is at least one selected from hydrogen peroxide, urea peroxide, calcium peroxide, sodium pyrophosphate peroxide and sodium percarbonate; the amounts of peroxide and silica are 0.3-3.5 wt.% and 5-20 wt.%, respectively, based on the total weight of the composition; and the purified silica contains 50 ppm or less of iron and is prepared by (a) mixing silica with hydrochloric acid solution and centrifuging the mixture, (b) washing precipitated and purified silica with purified water, and (c) drying and purifying the washed silica.
Abstract translation: 提供用于牙齿美白的牙膏组合物以通过抑制过氧化物的降解和使用无金属研磨剂释放活性氧来增加长期储存。 用于牙齿美白的牙膏组合物包括过氧化物和纯化的二氧化硅作为研磨剂，其中过氧化物是选自过氧化氢，过氧化脲，过氧化钙，焦磷酸钠和过碳酸钠中的至少一种。 基于组合物的总重量，过氧化物和二氧化硅的量分别为0.3-3.5重量％和5-20重量％; 纯化的二氧化硅含有50ppm以下的铁，并且通过（a）将二氧化硅与盐酸溶液混合并离心该混合物，（b）用纯化水洗涤沉淀的和纯化的二氧化硅，和（c）干燥并纯化洗涤的 二氧化硅。
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公开(公告)号：KR100673813B1
公开(公告)日：2007-01-25
申请号：KR1020050040939
申请日：2005-05-17
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 치아미백에 뛰어난 효능을 지닌 구강용 겔 제형 조성물에 관한 것으로, 보다 상세하게는 치아미백성분과 함께 필름형성제로 에틸셀룰로오즈, 에틸렌/아크릴산 공중합체, 에틸렌/아크릴산/비닐아세테이트 공중합체 및 에틸렌/프로필렌 공중합체로 이루어진 군으로부터 선택된 1종 이상의 비수용성 고분자를 함유하는 것을 특징으로 한다.
본 발명의 치아미백용 겔은 치아에 도포 즉시 비수용성 막을 형성하여 구강 내 타액에 대한 저항력과 치아표면에 대한 부착력을 높이고, 미백성분과의 접촉시간을 증대시켜 뛰어난 치아미백 효과를 제공하는 장점이 있다.
치아, 미백, 겔, 비수용성막-
Patent Agency Ranking
公开(公告)号：KR1020060062412A
公开(公告)日：2006-06-12
申请号：KR1020040101241
申请日：2004-12-03
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 구강 내 자극을 완화하고 청량감을 증진시키는 구강 세정용 조성물에 관한 것으로, 더욱 상세하게는 녹차 추출물 및 멘톨을 함유한 구강 세정용 조성물로서, 청량제(cooling agent)를 더 함유하여 구강 내 자극을 완화하고 청량감을 증진시키는 구강 세정용 조성물에 관한 것으로, 특히, 상기 녹차 추출물은 녹차 추출물이 캡슐 내에 싸인 녹차 추출물 캡슐의 형태로 존재함을 특징으로 한다.
본 발명의 상기 조성물은 구취제거 효과가 탁월한 녹차 추출물을 함유하고, 양치 후의 상쾌함을 부여하는 멘톨을 함유한 구강 세정용 조성물로서, 청량제를 더 함유하여 구강 내 자극을 완화하고 청량감을 증진시키는 효과가 있으며, 특히 녹차 추출물이 캡슐 내에 싸인 녹차 추출물 캡슐의 형태로 존재하여, 녹차 추출물의 제형 내 안정성을 향상시키는 효과가 있다.
구강, 자극, 청량감, 녹차 추출물, 멘톨, 청량제, 캡슐, 안정성-
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公开(公告)号：KR1020080027004A
公开(公告)日：2008-03-26
申请号：KR1020060092357
申请日：2006-09-22
Applicant: (주)아모레퍼시픽
Abstract: A method for preparing an oral granule is provided to obtain the oral composition which is added to an oral composition, thereby improving the stability of oral effective ingredients, being safe to oral mucosa and showing excellent periodental disease preventing, dental caries preventing and bad smell inhibiting effects. A method for preparing an oral granule comprises the steps of: (a) dissolving an oral effective ingredient in an aqueous binder solution where at least one selected from the group consisting of microcrystalline cellulose, white sugar and starch is dispersed to prepare a layering binder solution; and (b) coating an inert core with the layering binder solution using a fluid bed coater to prepare a spherical granule. The method further comprises a step of coating a layering binder solution including TiO2 or ZnO on the granule after the step(b). An oral composition comprises 0.05-5 wt.% of the prepared oral granule regarding the total weight of the composition. Further, the fluid bed coater uses a tangential spray system.
Abstract translation: 提供一种制备口服颗粒的方法，以获得口服组合物中的口服组合物，从而提高口腔有效成分的稳定性，对口腔粘膜是安全的，并且显示优异的牙周病预防，防止龋齿和抑制臭味 效果。 一种制备口服颗粒的方法包括以下步骤：（a）将口服有效成分溶解在粘合剂水溶液中，其中分散有微晶纤维素，白糖和淀粉中的至少一种，以制备分层粘合剂溶液 ; 和（b）使用流化床涂布机用分层粘合剂溶液涂覆惰性芯以制备球形颗粒。 该方法还包括在步骤（b）之后在颗粒上涂覆包含TiO 2或ZnO的分层粘合剂溶液的步骤。 关于组合物的总重量，口服组合物包含0.05-5重量％的制备的口服颗粒。 此外，流化床涂布机使用切向喷涂系统。
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公开(公告)号：KR100659139B1
公开(公告)日：2006-12-19
申请号：KR1020060003151
申请日：2006-01-11
Applicant: (주)아모레퍼시픽
Abstract: An oral composition having good antibacterial effects is provided to enhance antibacterial activity, prevent lowering of antibacterial activity, and bring up the antibacterial effects after its employment due to teethridge contraction and elasticity feeling. The oral composition having good antibacterial effects comprises 0.01-5 wt.% of cationic sterilizing agent, 4-10 wt.% of nonionic surfactant, and 0.01-2 wt.% of astringent, wherein the cationic sterilizing agent is cetyl pyridinium chloride; the nonionic surfactant is lauryl glucoside, cocamide DEA or polysorbate 20; and the astringent is a zinc compound such as zinc chloride, zinc oxide, zinc sulfate and zinc gluconate or a natural additive such as tannin.
Abstract translation: 提供具有良好抗菌效果的口腔用组合物以增强抗菌活性，防止抗菌活性的降低，并且由于牙齿收缩和弹性感而提高使用后的抗菌效果。 具有良好抗菌作用的口腔用组合物包含0.01-5重量％的阳离子型杀菌剂，4-10重量％的非离子型表面活性剂和0.01-2重量％的收敛剂，其中阳离子型杀菌剂为氯化十六烷基吡啶; 非离子表面活性剂是月桂基葡糖苷，椰油酰胺DEA或聚山梨酯20; 收敛剂是锌化合物如氯化锌，氧化锌，硫酸锌和葡萄糖酸锌或天然添加剂如单宁。
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公开(公告)号：KR1020030071010A
公开(公告)日：2003-09-03
申请号：KR1020020010513
申请日：2002-02-27
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/19 , A61K8/24 , A61K8/44 , A61Q11/00 , Y10S514/8995
Abstract: PURPOSE: Provided herein is a dental composition comprising calcium lactate as a calcium source, sodium phosphate dibasic anhydrous as a phosphorous source and EDTA-4Na for stabilization of the same within a formulation. Therefore, the composition can effectively recalcify the decalcification of enamel caused by dental caries generated within the teeth and further prevents teeth caries in advance. CONSTITUTION: A dental composition comprises 0.1 to 15.0% by weight of calcium lactate as a calcium source, 0.05 to 15.0% by weight of sodium phosphate dibasic anhydrous as a phosphorous source and 0.001 to 2.0% by weight of EDTA-4Na as a stabilizer for two materials. The dental composition is characterized in that it is maintained at pH value of 5.5, but could be increased to a pH of 5.5 or more by being mixed with the saliva in the mouth with a pH value of 7.0 when applied to the mouth.
Abstract translation: 目的：本文提供了一种牙科用组合物，其包含作为钙源的乳酸钙，作为磷源的无水磷酸氢二钠和用于在制剂中稳定其的EDTA-4Na。 因此，该组合物能够有效地重新钙化由牙齿内产生的龋齿引起的釉质脱钙，并进一步预防牙龋。 构成：牙科用组合物含有0.1〜15.0重量％的作为钙源的乳酸钙，0.05〜15.0重量％作为磷源的无水磷酸氢二钠，0.001〜2.0重量％的EDTA-4Na作为稳定剂 两种材料。 该牙科用组合物的特征在于，其pH值为5.5，但当施用于口腔时，通过与口腔中的唾液以7.0的pH值混合，可将其提高至5.5以上的pH。
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