公开(公告)号：KR1020130058546A

公开(公告)日：2013-06-04

申请号：KR1020110124614

申请日：2011-11-25

Applicant: 가톨릭대학교 산학협력단

Inventor： 김병학 ,  김태윤

IPC: A61K8/49 ,  A61K8/35 ,  A61K8/34 ,  A61Q19/00

CPC classification number: A61K8/18 ,  A61K8/97 ,  A61K36/48 ,  A61K2236/33 ,  A61Q19/00 ,  A61Q19/005 ,  Y10S514/844 ,  Y10S514/857 ,  Y10S514/863

Abstract: PURPOSE: A cosmetic composition containing kurarinone or a Sophora flavescens extract is provided to suppress cell activity causing dermatitis including atopic dermatitis, psoriasis, and contact dermatitis. CONSTITUTION: A cosmetic composition for preventing and treating psoriasis, atopic dermatitis, or contact dermatitis contains kurarinone of chemical formula 1 or a salt thereof as an active ingredient. The cosmetic composition contains a Sophora flavescens extract as an active ingredient. The extract contains a compound selected from a group consisting of kurarinol, kurarinone, kushenol N, kushenol I, kushenol M, kuraridin, 8-lavandulylkaempferol, (2S)-2'-methoxykurarinone, sophoraflavanone G, trifolirhizin, (-)maackiain, variabilin, medicarpin, and sophoracarpan A. The extract is prepared using a solvent selected from a group consisting of water, C1-C6 alcohol, ethyl acetate, methylene chloride, dichloromethane, chloroform, n-Hexane, diethylether, acetone, and benzene.

Abstract translation: 目的：提供含有kurarinone或苦参提取物的化妆品组合物，以抑制引起皮炎的细胞活性，包括特应性皮炎，牛皮癣和接触性皮炎。 构成：用于预防和治疗牛皮癣，特应性皮炎或接触性皮炎的化妆品组合物含有化学式1的kurarinone或其盐作为活性成分。 化妆品组合物含有苦参提取物作为活性成分。 提取物含有选自kurarinol，kurarinone，kushenol N，kushenol I，kushenol M，kuraridin，8-lavandulylkaempferol，（2S）-2'-甲氧基葫芦素，槐花素G，三叶草嗪，（ - ）ma ain， ，药草和槐花A.使用选自水，C 1 -C 6醇，乙酸乙酯，二氯甲烷，二氯甲烷，氯仿，正己烷，乙醚，丙酮和苯的溶剂制备提取物。