신규한 타액선-이식 종양 동물모델
    13.
    发明公开
    신규한 타액선-이식 종양 동물모델 有权
    一种新的唾液移植动物模型

    公开(公告)号:KR1020110051713A

    公开(公告)日:2011-05-18

    申请号:KR1020090108439

    申请日:2009-11-11

    Inventor: 박영욱 김성곤

    Abstract: PURPOSE: A salivary gland-transplantation animal model is provided to ensure easy accessability and to transplant to regional lymph nodes or distant site. CONSTITUTION: A method for analyzing tumor metastasis mode using a salivary gland-transplantation animal model comprises: a step of transplanting tumor cells to salivary gland of a normal animal to induce tumor; and a step of measuring tumor cell metastasis in a tissue or organic besides salivary gland. A method for screening an anticancer drug using the salivary gland-transplantation tumor animal model comprises: a step of transplanting tumor cells to salivary gland of a normal animal except for human body; a step of administering anticancer drug candidate to the animal; and a step of measuring growth or metastasis of the tumor cells.

    Abstract translation: 目的:提供唾液腺移植动物模型,以确保易于接近和移植到局部淋巴结或远处。 构成:使用唾液腺移植动物模型分析肿瘤转移模式的方法包括:将肿瘤细胞移植到正常动物的唾液腺以诱导肿瘤的步骤; 以及测量除唾液腺以外的组织或有机物中的肿瘤细胞转移的步骤。 使用唾液腺移植肿瘤动物模型筛选抗癌药物的方法包括:将肿瘤细胞移植到除人体外的正常动物唾液腺的步骤; 向动物施用抗癌药物候选者的步骤; 以及测量肿瘤细胞生长或转移的步骤。

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