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公开(公告)号：KR1020120111467A
公开(公告)日：2012-10-10
申请号：KR1020110029951
申请日：2011-03-31
Applicant: 고려대학교 산학협력단
CPC classification number: G01N27/3278
Abstract: PURPOSE: A nano-wire in which diamonds are deposited and a manufacturing method thereof are provided to have high specific surface area suitable for the bio-sensor. CONSTITUTION: A nano-wire in which diamonds are deposited covers outer circumference of the nano-wire. The nano-wire is coated with first polymers having polarity. The diamond particle is coated with second polymers having opposite polarity from the first polymers. A method of pre-treating the nano-wire using static charge self-assembly method of the nano-diamond particle comprises the following steps: synthesizing nano-wires; coating first polymers having polarity on the outer circumference of the nano-wire; coating the surface of the nano-diamond particle with the second polymers having the opposite polarity from the static charge of the nano-diamond particle; and dipping the nano-wire into a solution in which the nano-diamond particle is dispersed. [Reference numerals] (AA,BB) Nano-diamond particle chargeB; (CC,DD) Nano-diamond particle chargeA; (EE,FF) Carbon nano-tube chargeA
Abstract translation: 目的：提供其中沉积有金刚石的纳米线及其制造方法以具有适于生物传感器的高比表面积。 构成：其中沉积有金刚石的纳米线覆盖纳米线的外周。 纳米线涂覆有具有极性的第一种聚合物。 金刚石颗粒用与第一聚合物相反极性的第二聚合物涂覆。 使用纳米金刚石颗粒的静电自组装方法对纳米线进行预处理的方法包括以下步骤：合成纳米线; 涂覆在纳米线的外周上具有极性的第一聚合物; 用具有与纳米金刚石颗粒的静电荷相反的极性的第二聚合物涂覆纳米金刚石颗粒的表面; 并将纳米线浸入其中分散有纳米金刚石颗粒的溶液中。 （参考号）（AA，BB）纳米金刚石颗粒电荷B; （CC，DD）纳米金刚石颗粒电荷A; （EE，FF）碳纳米管电荷
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公开(公告)号：KR101188172B1
公开(公告)日：2012-10-05
申请号：KR1020100048934
申请日：2010-05-26
Applicant: 고려대학교 산학협력단
IPC: G01N27/327 , G01N33/66 , G01N27/417
Abstract: 본 발명은 금속 나노입자가 증착된 그래핀 시트의 다이아몬드 박막 전극을 이용한 전기화학적 바이오센서 및 그 제조방법에 관한 것이다. 본 발명에 따른 바이오센서는, 기판; 효소 반응이 발생되는 작업전극 및 상기 작업전극과의 전기적 출력 차이를 검출하기 위한 상대전극을 포함하는 전기화학적 바이오센서로서, 상기 작업전극은, 불순물 도핑된 다이아몬드층; 상기 불순물 도핑된 다이아몬드층 상에 형성된 그래핀층; 및 상기 그래핀층 상에 형성된 금속 나노입자층을 포함하는 것이 특징이다.
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公开(公告)号：KR1020100059577A
公开(公告)日：2010-06-04
申请号：KR1020080118399
申请日：2008-11-26
Applicant: 고려대학교 산학협력단
IPC: G01N27/327 , G01N27/26 , G01N33/48 , B82B3/00
Abstract: PURPOSE: A high-sensitivity porous glucose biosensor including a porous conductive polymer nano-rod structure and a preparing method thereof are provided to prevent the reduction of electrode area due to the miniaturization of device. CONSTITUTION: A high-sensitivity porous glucose biosensor comprises a reference electrode, a relative electrode and a working electrode. The working electrode comprises conductive polymer nano-rods and a porous silicon material. A Au layer is laminated on the top of the silicon material and a Ti layer is laminated between the silicon material and the Au layer. The conductive polymer nano-rods are formed on the top of the Au layer.
Abstract translation: 目的：提供一种包括多孔导电聚合物纳米棒结构的高灵敏度多孔葡萄糖生物传感器及其制备方法，以防止由于器件的小型化引起的电极面积的减少。 构成：高灵敏度多孔葡萄糖生物传感器包括参比电极，相对电极和工作电极。 工作电极包括导电聚合物纳米棒和多孔硅材料。 在硅材料的顶部层叠Au层，并且在硅材料和Au层之间层压Ti层。 导电聚合物纳米棒形成在Au层的顶部。
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Patent Agency Ranking
公开(公告)号：KR1020100059575A
公开(公告)日：2010-06-04
申请号：KR1020080118397
申请日：2008-11-26
Applicant: 고려대학교 산학협력단
Abstract: PURPOSE: An electrochemical sensor using CuO nano-flowers for hydrogen peroxide detection is provided to detect even low concentration of hydrogen peroxide and elongate the storage by not including ferment. CONSTITUTION: An electrochemical sensor using CuO nano-flowers for hydrogen peroxide detection comprises a reference electrode, a working electrode, and a relative electrode. The reference electrode is made of SCE(Saturated Calomel Electrode). CuO nano-flowers having hydrogen peroxide selectivity is provided on the working electrode, wherein the length of the single crystal petal of the CuO nano-flowers is 100~500nm and the thickness is 50nm or less. The relative electrode is made of Pt.
Abstract translation: 目的：提供一种使用CuO纳米花进行过氧化氢检测的电化学传感器，用于检测甚至低浓度的过氧化氢，并通过不含发酵来延长储存。 构成：使用CuO纳米花进行过氧化氢检测的电化学传感器包括参比电极，工作电极和相对电极。 参比电极由SCE（饱和碳酸钙电极）制成。 在工作电极上设置具有过氧化氢选择性的CuO纳米花，其中CuO纳米花的单晶花瓣的长度为100〜500nm，厚度为50nm以下。 相对电极由Pt制成。
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15.发明授权금 나노입자가 분산된 과산화 전도성 고분자 나노선의 다이아몬드 박막 전극을 이용한 도파민 검출센서 有权选择性伏安法在抗坏血酸存在下金纳米颗粒分散的聚苯胺纳米复合材料改性BDD电极上的多巴胺检测
公开(公告)号：KR101373578B1
公开(公告)日：2014-03-13
申请号：KR1020120006761
申请日：2012-01-20
Applicant: 고려대학교 산학협력단
Abstract: 본 발명은 아스코르빅 산의 영향을 받지 않고, 도파민을 선택적으로 검출할 수 있는 금 나노입자가 분산된 과산화 전도성 고분자 나노선의 다이아몬드 박막 전극을 이용한 전기화학 센서를 제공한다. 본 발명에 따른 센서는 0.15 내지 500 μM에 이르는 넓은 농도범위 내에서 선형성을 보이며, 0.131μA/μM의 높은 감도와 0.03μM의 낮은 검출한계를 보이며 도파민을 감지할 수 있다.
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16.发明公开
公开(公告)号：KR1020130085737A
公开(公告)日：2013-07-30
申请号：KR1020120006761
申请日：2012-01-20
Applicant: 고려대학교 산학협력단
Abstract: PURPOSE: A Dopamine detection sensor using a diamond thin film electrode of hydrogen conductive polymer nano wires in which gold nano particles are dispersed is provided to show linearity in a wide range of density, and to detect Dopamine as showing high sensitivity and low detection limit. CONSTITUTION: A Dopamine detection sensor using a diamond thin film electrode of hydrogen conductive polymer nano wires in which gold nano particles are dispersed includes a working electrode, a counterpart electrode and a reference electrode. The counterpart electrode is formed with a platinum wire. The reference electrode is formed with silver and silver chloride. The working electrode is a Boron-doped diamond (BPD) thin film electrode. Conductive polymer combined through electrolytic polymerization reaction is included in the surface of the thin film electrode. Gold nano particles are coated in the conductive polymer.
Abstract translation: 目的：提供使用金纳米颗粒分散的导电聚合物纳米线的金刚石薄膜电极的多巴胺检测传感器，以在宽范围的浓度范围内显示线性，并检测多巴胺显示出高灵敏度和低检测限。 构成：使用其中分散有金纳米颗粒的导电聚合物纳米线的金刚石薄膜电极的多巴胺检测传感器包括工作电极，对应电极和参比电极。 对应电极由铂丝形成。 参比电极由银和氯化银形成。 工作电极是硼掺杂金刚石（BPD）薄膜电极。 通过电解聚合反应结合的导电聚合物包括在薄膜电极的表面中。 金纳米颗粒被涂覆在导电聚合物中。
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公开(公告)号：KR1020110129528A
公开(公告)日：2011-12-02
申请号：KR1020100048934
申请日：2010-05-26
Applicant: 고려대학교 산학협력단
IPC: G01N27/327 , G01N33/66 , G01N27/417
Abstract: PURPOSE: An electrochemical biosensor and a manufacturing method thereof are intended to provide accurate measurement using a small amount of materials and enable high sensitivity of an electrochemical biosensor to be manufactured with high reproducibility. CONSTITUTION: An electrochemical biosensor(100) comprises a substrate(10), a working electrode(20), and a counter electrode(40). Enzyme reaction occurs at the working electrode. The counter electrode detects electrical output difference from the working electrode. The working electrode comprises a diamond layer, a graphene layer and a metallic nano-particle layer. Dopant is doped on the diamond layer. The graphene layer is formed on the doped diamond layer. The metallic nano-particle layer is formed on the graphene layer.
Abstract translation: 目的：电化学生物传感器及其制造方法旨在使用少量的材料提供精确的测量，并且能够以高再现性制造电化学生物传感器的高灵敏度。 构成：电化学生物传感器（100）包括衬底（10），工作电极（20）和对电极（40）。 酶反应发生在工作电极处。 对电极检测与工作电极的电输出差异。 工作电极包括金刚石层，石墨烯层和金属纳米颗粒层。 掺杂剂掺杂在金刚石层上。 在掺杂的金刚石层上形成石墨烯层。 在石墨烯层上形成金属纳米粒子层。
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公开(公告)号：KR1020100107963A
公开(公告)日：2010-10-06
申请号：KR1020090026361
申请日：2009-03-27
Applicant: 고려대학교 산학협력단
Abstract: PURPOSE: An electrochemical hydrogen peroxide biosensor based on Ag nanowires modified electrode and a manufacturing method for the same are provided to detect peroxide of hydrogen of a lower concentration. CONSTITUTION: A manufacturing method of an electrochemical hydrogen peroxide biosensor based on Ag nanowires modified electrode is as follows. A nanosilver-layer is formed on a gold electrode. The gold electrode with nanosilver-layer is dipped in cysteamine solution in order to form a cysteamine layer on the nanosilver-layer. The surface of electrode with a cysteamine layer is exposed to glutaldehyde solution in order to combine cysteamine and glutaldehyde. The glutaldehyde treated electrode is dipped in solution containing enzyme in order to combine enzyme and electrode.
Abstract translation: 目的：提供一种基于Ag纳米线修饰电极的电化学过氧化氢生物传感器及其制备方法，用于检测较低浓度的氢过氧化物。 构成：基于Ag纳米线修饰电极的电化学过氧化氢生物传感器的制造方法如下。 在金电极上形成纳米银层。 将具有纳米银层的金电极浸入半胱胺溶液中，以在纳米银层上形成半胱胺层。 将具有半胱胺层的电极表面暴露于戊二醛溶液中，以便结合半胱胺和戊二醛。 将经过戊二醛处理的电极浸入含酶溶液中以结合酶和电极。
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