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公开(公告)号：KR1020150005165A
公开(公告)日：2015-01-14
申请号：KR1020130078589
申请日：2013-07-04
Applicant: 다이아텍코리아 주식회사
IPC: C07D487/22 , A61K31/409 , A61P35/00
Abstract: 본 발명은 신규한 클로린 e6 모노메틸에스테르, 그 제조방법 및 그 용도에 관한 것이다.
Abstract translation: 本发明涉及一种新的二氢卟酚e6单甲酯，其制备方法和用途。 本发明的二氢卟酚e6单甲酯由化学式1或2表示，并且包括在用于治疗或预防癌症作为活性成分的组合物中。 二氢卟酚e6单甲酯的制备方法包括以下步骤：（a）从螺旋藻获得氯仿提取液; （b）通过向氯霉素提取物溶液中加入酸并使其相互反应获得鞘内营养素; （c）并通过将底物处理到鞘磷脂来合成二氢卟酚e6的钠盐。
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公开(公告)号：KR101412186B1
公开(公告)日：2014-06-27
申请号：KR1020110140499
申请日：2011-12-22
Applicant: 건국대학교 산학협력단 , 다이아텍코리아 주식회사
IPC: C07C321/08 , C07C315/06 , G01N30/72
Abstract: 본 발명은 중수소로 치환된 올리고에틸렌티올분자 및 그 제조방법에 관한 것이다.
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公开(公告)号：KR1020140012927A
公开(公告)日：2014-02-04
申请号：KR1020130165809
申请日：2013-12-27
Applicant: 다이아텍코리아 주식회사
CPC classification number: C12Q1/6876 , C12N15/11 , C12Q2600/142
Abstract: The present invention relates to a system for diagnosing single nucleotide polymorphism using mass analysis. Provided is a kit for diagnosing single nucleotide polymorphism, wherein the kit includes a peptide nucleic acid probe (PNA) composition having a nucleotide sequence of SEQ ID NO 5 to 7 and a primer composition having a nucleotide sequence of SEQ ID NO 3 or 4.
Abstract translation: 本发明涉及使用质量分析诊断单核苷酸多态性的系统。 提供了用于诊断单核苷酸多态性的试剂盒，其中所述试剂盒包括具有SEQ ID NO：5至7的核苷酸序列的肽核酸探针（PNA）组合物和具有SEQ ID NO 3或4的核苷酸序列的引物组合物。
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Patent Agency Ranking
公开(公告)号：KR1020130107429A
公开(公告)日：2013-10-02
申请号：KR1020120029185
申请日：2012-03-22
Applicant: 다이아텍코리아 주식회사
CPC classification number: C12Q1/6827 , C12Q1/6888 , C12Q1/706 , C12Q2525/107
Abstract: PURPOSE: A single nucleotide polymorphism (SNP) diagnosis system using mass spectrometry is provided to quickly and accurately diagnose various diseases using a small amount of a sample. CONSTITUTION: A method for detecting SNP at a single mutational site or a multiplex mutation site comprises the steps of: hybridizing a specific peptide nucleic acid (PNA) probe with DNA; treating the prepared DNA-PNA complex with enzyme or chemical materials to cleave the DNA; and measuring the mass of isolated PNA by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF). The PNA probe has base sequences of sequence numbers 5-7. A primer composition has a base sequence of sequence number 3 or 4. A kit for diagnosing SNP contains the PNA probe and the primer composition.
Abstract translation: 目的：提供使用质谱法的单核苷酸多态性（SNP）诊断系统，使用少量样品快速准确地诊断各种疾病。 构成：在单个突变位点或多重突变位点检测SNP的方法包括以下步骤：将特异性肽核酸（PNA）探针与DNA杂交; 用酶或化学物质处理制备的DNA-PNA复合物以切割DNA; 并通过基质辅助激光解吸/电离飞行时间（MALDI-TOF）测量分离的PNA的质量。 PNA探针具有序列号5-7的碱基序列。 底漆组合物具有序列号3或4的碱基序列。用于诊断SNP的试剂盒含有PNA探针和底漆组合物。
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公开(公告)号：KR101586849B1
公开(公告)日：2016-01-19
申请号：KR1020130066944
申请日：2013-06-12
Applicant: 다이아텍코리아 주식회사
IPC: C07D487/22 , A61K31/409 , A61P35/00
Abstract: 본발명은신규한클로린 e6의트로메타민염, 및그 제조방법및 그용도에관한것이다.
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公开(公告)号：KR1020150133016A
公开(公告)日：2015-11-27
申请号：KR1020140059783
申请日：2014-05-19
Applicant: 다이아텍코리아 주식회사 , 건국대학교 산학협력단
Abstract: 본발명은내열성 DNA 중합효소를이용한유전자변이검출방법에관한것으로, 본발명에따르면비교적간단하게유전자변이를검출할수 있으며, 다양한형광이나매스태그시퀀스를도입하여다중검출에사용할수 있다.
Abstract translation: 本发明涉及使用耐热DNA聚合酶检测遗传突变的方法。 根据本发明，用于检测遗传突变的方法相对简单，并且通过采用各种荧光物质和质量标签序列用于多重检测。
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公开(公告)号：KR1020150005166A
公开(公告)日：2015-01-14
申请号：KR1020130078590
申请日：2013-07-04
Applicant: 다이아텍코리아 주식회사
IPC: A61K31/409 , A61K9/08 , A61K47/30
CPC classification number: A61K31/409 , A61K9/0019 , A61K41/0057 , A61K47/10
Abstract: 본발명은광민감제의주사가능한조성물에관한것으로, 더욱상세하게는클로린또는클로린염의용해제를포함하는광역학치료약물조성물에관한것이다.
Abstract translation: 本发明涉及能够注射光敏剂的组合物。 具体地，在本发明中，提供了包含氯或氯盐增溶剂的光动力疗法（PDT）的药物组合物。 本发明的组合物包含（a）氯e6或氯e6衍生物; 和（b）至少一种氯e6或氯e6衍生物的增溶剂。
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公开(公告)号：KR101449599B1
公开(公告)日：2014-10-13
申请号：KR1020130066945
申请日：2013-06-12
Applicant: 다이아텍코리아 주식회사 , 건국대학교 산학협력단
IPC: C12N5/071 , A61K35/28 , A61K31/409 , A61K47/48 , A61K49/04
CPC classification number: C12N5/0692 , A61K31/409 , A61K35/28 , A61K47/50 , A61K49/04
Abstract: The present invention relates to an adult stem cell including a photosensitizer and an agent to treat cancer cells. The stem cell is produced by a method including a step of treating a mesenchymal stem cell with tromethamine. A method in the new concept of treating cancer using the adult stem as a carrier for the photosensitizer applies an agent transferring and the agent capable of targeting cancer cells, and has the advantages of treating both using the adult stem cell and photodynamic therapy.
Abstract translation: 本发明涉及包含光敏剂和治疗癌细胞的药剂的成体干细胞。 干细胞通过包括用氨丁三醇治疗间充质干细胞的步骤的方法产生。 使用成人干细胞作为光敏剂载体的治疗癌症的新概念中的方法应用能够靶向癌细胞的药剂转移剂和药剂，并且具有使用成体干细胞和光动力疗法治疗两者的优点。
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