公开(公告)号：KR1020120004806A

公开(公告)日：2012-01-13

申请号：KR1020100065489

申请日：2010-07-07

Applicant: 서울대학교산학협력단

Inventor： 김재범 ,  김아영

IPC: A61K48/00

CPC classification number: A61K48/00 ,  A61K48/0058 ,  A61K2121/00

Abstract: PURPOSE: A composition containing microRNA-27alpha for anti-obesity is provided to PPAR gamma expression and to control adipocyte differentiation. CONSTITUTION: A composition for anti-obesity contains microRNA-27alpha of sequence number 1 as an active ingredient. A method for suppressing obesity of animal except for human comprises a step of enhancing microRNA-27alpha in cells. A method for suppressing obesity comprises a step of administering effective amount of microRNA-27alpha. The microRNA-27alpha has a sequence of sequence number 1.

Abstract translation: 目的：提供含有用于抗肥胖症的microRNA-27alpha的组合物用于PPARγ表达并控制脂肪细胞分化。 构成：抗肥胖组合物含有序列号1的microRNA-27alpha作为活性成分。 除人以外抑制动物肥胖的方法包括增强细胞中的microRNA-27alpha的步骤。 抑制肥胖症的方法包括施用有效量的微小RNA-27α的步骤。 microRNA-27alpha具有序列号1的序列。