헬리카제 억제제 다중 스크리닝 방법 및 스크리닝용 조성물
    11.
    发明公开
    헬리카제 억제제 다중 스크리닝 방법 및 스크리닝용 조성물 无效
    多氯联苯抑制剂和筛选组合物的筛选方法

    公开(公告)号:KR1020140094189A

    公开(公告)日:2014-07-30

    申请号:KR1020130006614

    申请日:2013-01-21

    Inventor: 민달희

    CPC classification number: C12Q1/6876 C01B32/23 C12N15/11 C12Q1/34 C12Q1/6888

    Abstract: The present invention relates to a helicase inhibitor multi-screening method and a composition for screening using graphene oxide. The helicase inhibitor multi-screening method comprises the step of adding a sample to a compound comprising two or more different helicases; two or more different double-stranded nucleic acids containing different fluorescent dyes from each other at one end as a substrate of each of two or more different helicases; and graphene oxide, and of measuring a fluorescence intensity of the compound.

    Abstract translation: 本发明涉及一种解旋酶抑制剂多筛选方法及使用氧化石墨烯筛选的组合物。 解旋酶抑制剂多筛选方法包括将样品添加到包含两种或更多种不同解旋酶的化合物中的步骤; 两种或多种不同的双链核酸,其一端含有彼此不同的荧光染料,作为两种或多种不同解旋酶中的每一种的底物; 和氧化石墨烯,以及测定化合物的荧光强度。

    약물전달용 조성물 및 이를 이용한 약물전달방법
    12.
    发明公开
    약물전달용 조성물 및 이를 이용한 약물전달방법 有权
    用于药物递送和药物递送方法的组合物

    公开(公告)号:KR1020140010285A

    公开(公告)日:2014-01-24

    申请号:KR1020120077308

    申请日:2012-07-16

    Inventor: 민달희

    Abstract: The present invention relates to a composition for drug delivery which includes RNA absorbed to a porous silica nonaparticle with expanded pores, and a drug delivery method using the same. The RNA includes siRNA, miRNA, tRNA, mRNA, sRNA, or rRNA. [Reference numerals] (AA) Porous silica nonaparticle with expanded pores; (BB) Absorbing into a cell

    Abstract translation: 本发明涉及用于药物递送的组合物,其包括被吸收到具有扩张孔的多孔二氧化硅非粒子的RNA和使用其的药物递送方法。 RNA包括siRNA,miRNA,tRNA,mRNA,sRNA或rRNA。 (附图标记)(AA)具有膨胀孔的多孔二氧化硅非颗粒; (BB)吸收细胞

    핵산 검출용 조성물 및 이를 이용한 핵산 검출 방법
    13.
    发明公开
    핵산 검출용 조성물 및 이를 이용한 핵산 검출 방법 有权
    用于检测核酸的组合物和使用其的核酸检测方法

    公开(公告)号:KR1020130124196A

    公开(公告)日:2013-11-13

    申请号:KR1020130045536

    申请日:2013-04-24

    Abstract: The present invention relates to a composition containing a PNA probe containing fluorescent materials, which is adsorbed to graphene oxide for detecting nucleic acids and a method for detecting nucleic acids using the same. Provided is a composition for nucleic acids, which enables multi detection and real-time detection of target nucleic acids using the characteristics of graphene oxide, is adsorbed to graphene oxide, and contains a PNA probe containing fluorescent materials; and a method for detecting nucleic acids using the same. [Reference numerals] (AA) Extinction of fluorescence;(BB) Target miRNA and complementary and fluorescence material including single strand PNA;(CC) Graphene oxide (GO);(DD) Target miRNA;(EE) Cytoplasm;(FF) Recover of fluorescence

    Abstract translation: 本发明涉及包含含有荧光材料的PNA探针的组合物,其被吸附到用于检测核酸的氧化石墨烯上,以及使用该荧光材料检测核酸的方法。 提供了一种用于核酸的组合物,其使用氧化石墨烯的特征能够多次检测和实时检测靶核酸,被吸附到氧化石墨烯上,并且含有含荧光材料的PNA探针; 以及使用其的核酸检测方法。 (AA)灭活荧光;(BB)目标miRNA和包括单链PNA的互补和荧光材料;(CC)石墨烯氧化物(GO);(DD)靶miRNA;(EE)细胞质;(FF) 的荧光

    핵산의 검출 방법 및 핵산 검출용 키트
    14.
    发明公开
    핵산의 검출 방법 및 핵산 검출용 키트 有权
    用于检测核酸的方法和用于检测核酸的试剂盒

    公开(公告)号:KR1020150128612A

    公开(公告)日:2015-11-18

    申请号:KR1020150064498

    申请日:2015-05-08

    Inventor: 민달희 이지언

    Abstract: 본원은핵산의검출방법및 핵산검출용키트에관한것이다.

    Abstract translation: 本发明涉及检测核酸的方法,以及用于检测核酸的试剂盒。 检测核酸的方法包括以下步骤:制备包含靶核酸的样品; 加入含有磷光物质的肽核酸(PNA)探针,并与靶核酸互补,并将其混合; 并向混合物中加入氧化石墨烯。

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