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公开(公告)号:KR101520614B1
公开(公告)日:2015-05-19
申请号:KR1020130088006
申请日:2013-07-25
Applicant: 서울대학교산학협력단
CPC classification number: C12Q1/34 , C12Q1/37 , G01N33/57484 , G01N2333/98 , G01N2440/38 , G01N2560/00 , G01N2800/7028
Abstract: 본원은 N-연결당화 (N-linked glycosylation) 모티브를포함하는단백질에서탈당화펩타이드단편및 비당화펩타이드단편의비율의대조군과의차이에의한암 진단방법을개시한다. 본원에따른단백질의당화비율의검출을통한암의진단방법은하나이상의기존마커를이용하여높은특이성및 민감도로암을진단할수 있으며, 또한암의진단을위한새로운마커발굴에도용이하게사용될수 있다.
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公开(公告)号:KR1020140040423A
公开(公告)日:2014-04-03
申请号:KR1020120107045
申请日:2012-09-26
Applicant: 엘지전자 주식회사 , 서울대학교산학협력단
CPC classification number: G01N33/6896 , C12Q1/6883 , C12Q2600/158 , G01N33/6893 , G01N2800/164 , G01N33/5302 , G01N33/5308 , G01N2800/04
Abstract: The present invention relates to a marker for diagnosing diabetic retinopathy and its use, and more specifically, to a marker which is used to diagnose a diabetic retinopathy patient and to determine progress of diseases, a composition for diagnosing diabetic retinopathy containing a pharmaceutical formulation for measuring genes or protein associated with the marker, and its use. According to an embodiment of the present invention, the marker for diagnosing diabetic retinopathy is selected from among Zinc-Alpha-2-Glycoprotein (ZAG), Peroxiredoxin 2 (PRDX2), Myocilin (MYOC), and Haptoglobin (HP).
Abstract translation: 本发明涉及用于诊断糖尿病性视网膜病变的标记及其用途,更具体地,涉及用于诊断糖尿病性视网膜病变患者并确定疾病进展的标记物,用于诊断糖尿病性视网膜病变的组合物,其含有用于测量的药物制剂 与标记物相关的基因或蛋白质及其用途。 根据本发明的一个实施方案,用于诊断糖尿病性视网膜病变的标记物选自Zn-α-2-糖蛋白(ZAG),过氧化还原毒素2(PRDX2),Myocilin(MYOC)和Haptoglobin(HP)。
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公开(公告)号:KR1020140000977A
公开(公告)日:2014-01-06
申请号:KR1020120069027
申请日:2012-06-27
Applicant: 엘지전자 주식회사 , 서울대학교산학협력단
CPC classification number: G01N33/6893 , C12Q1/6881 , C12Q1/6883 , C12Q2600/158 , G01N2333/4716 , G01N2333/8114 , G01N2800/164 , G01N33/5302
Abstract: The present invention relates to a marker used for diagnosing diabetes retinopathy patients and determining progress; a composition for diagnosing diabetes retinopathy including a medicine measuring a protein level or a gene related to the marker; and a purpose thereof. One or more markers for diagnosing the diabetes retinopathy are selected among complement C7, Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2), and complement C5. [Reference numerals] (AA) (Left) non-proliferative diabetic retinopathy (NPDR); (BB) (Right) proliferative diabetic retinopathy (PDR)
Abstract translation: 本发明涉及用于诊断糖尿病视网膜病变并确定进展的标记物; 用于诊断糖尿病视网膜病变的组合物,包括测量蛋白质水平的药物或与所述标记物相关的基因; 及其目的。 用于诊断糖尿病视网膜病变的一种或多种标志物选自补体C7,间-α-胰蛋白酶抑制剂重链H2(ITIH2)和补体C5。 (AA)(左)非增殖性糖尿病视网膜病变(NPDR); (BB)(右)增殖性糖尿病视网膜病变(PDR)
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