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公开(公告)号：KR1020140137882A
公开(公告)日：2014-12-03
申请号：KR1020130059091
申请日：2013-05-24
Applicant: 가톨릭대학교 산학협력단
IPC: A61K31/706 , A61K31/7068 , A61P19/00
CPC classification number: A61K31/706 , A61K31/7068
Abstract: 본 발명은 5-아자싸이티딘(5-Azacitidine) 및/또는 트리코스타틴 A (Trichostatin A)를 이용하여, 중간엽줄기세포를 신경세포, 연골세포 및 골세포 등 다양한 계통의 세포로 분화 유도하는 기술에 관한 것이다.
Abstract translation: 本发明涉及通过使用5-氮杂胞苷和/或曲古抑菌素A来诱导间充质干细胞分化成各种系统如神经细胞，软骨细胞和骨细胞的细胞的技术。
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公开(公告)号：KR1020120096220A
公开(公告)日：2012-08-30
申请号：KR1020110015494
申请日：2011-02-22
Applicant: 숙명여자대학교산학협력단
IPC: C12N15/12 , C12N15/85 , C12N5/10 , A01K67/027
Abstract: PURPOSE: An enhancer factor of epha7 gene, expression vector including the same, and a host organism transformed by the same are provided to be specified in diencephalon and mesencephalon central line. CONSTITUTION: An enhancer factor of epha7 gene comprises a nucleic acid molecule including the whole base sequence described in the sequence number 3(SEQ ID NO:3), a nucleic acid molecule composed of 70% or more consecutive parts of the base sequence described in the sequence number3; and a nucleic acid molecule having more than 70% of the sequence homology with the base sequence of the sequence number 3. The nucleic acid molecule including the whole base sequence described in the sequence number 3 is the nucleic acid molecule including the base sequence of the sequence number 1. The nucleic acid molecule including the whole base sequence described in the sequence number 3 is the nucleic acid molecule including the base sequence of the sequence number 2.
Abstract translation: 目的：提供epha7基因的增强因子，包含其的表达载体和由其转化的宿主生物体，以在间脑和中脑线中规定。 构成：epha7基因的增强因子包含核酸分子，其包含序列号3（SEQ ID NO：3）中所述的全部碱基序列，由70％以上的连续部分的碱基序列组成的核酸分子， 序列号3; 和与序列号3的碱基序列具有70％以上序列同源性的核酸分子。包含序列号3中所述的全部碱基序列的核酸分子是包含以下序列的碱基序列的核酸分子： 序列号1.包含序列号3中所述的整个碱基序列的核酸分子是包含序列号2的碱基序列的核酸分子。
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公开(公告)号：KR101342522B1
公开(公告)日：2013-12-17
申请号：KR1020110015494
申请日：2011-02-22
Applicant: 숙명여자대학교산학협력단
IPC: C12N15/12 , C12N15/85 , C12N5/10 , A01K67/027
Abstract: 본발명은 EphA7 유전자의인핸서인자및 그것의용도를개시한다. 구체적으로본 발명은간뇌와중뇌중심선에특이적인 EphA7 유전자의인핸서인자, 그인핸서인자를포함하는발현벡터, 그발현벡터로형질전환된숙주유기체, 그형질전환된숙주유기체의제조방법을개시한다.
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