4-하이드록시 타목시펜 유사체 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 간질환의 치료 또는 예방용 조성물
    11.
    发明公开
    4-하이드록시 타목시펜 유사체 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 간질환의 치료 또는 예방용 조성물 有权
    用于治疗或预防包含4-羟基酪氨酸类似物或其药学上可接受的盐作为有效成分的肝脏失败的组合物

    公开(公告)号:KR1020120134939A

    公开(公告)日:2012-12-12

    申请号:KR1020110054178

    申请日:2011-06-03

    Abstract: PURPOSE: A composition containing a 4-hydroxy tamoxifen analog for preventing or treating liver diseases is provided to reduce GOT(glutamyl oxaloacetic transaminase) and GPT(glutamyl pyruvate transaminase) level and to prevent and treat liver diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating liver diseases contains a 4-hydroxy tamoxifen analog of chemical formula 1 or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition additionally contains a pharmaceutically acceptable carrier. The liver diseases are non-alcoholic or alcoholic fatty liver. The pharmaceutical composition reduces fat accumulation in the liver. The non-alcoholic fatty liver is non-alcoholic steatohepatitis or late phase fibrosis liver diseases. A food composition for preventing or treating liver diseases contains 4-hydroxy tamoxifen analog of chemical formula 1 or sitologically acceptable salt thereof as an active ingredient.

    Abstract translation: 目的:提供含有用于预防或治疗肝脏疾病的4-羟基三苯氧胺类似物的组合物,用于减少GOT(谷氨酰氧乙酰转氨酶)和GPT(戊酰丙酮酸转氨酶)水平,并预防和治疗肝脏疾病。 构成:用于预防或治疗肝脏疾病的药物组合物含有化学式1的4-羟基他莫昔芬类似物或其药学上可接受的盐作为活性成分。 药物组合物另外含有药学上可接受的载体。 肝脏疾病是非酒精性或酒精性脂肪肝。 该药物组合物可减少肝脏中的脂肪堆积。 非酒精性脂肪肝是非酒精性脂肪性肝炎或晚期纤维化肝病。 用于预防或治疗肝脏疾病的食物组合物含有化学式1的4-羟基三苯氧胺类似物或其可以使用的盐作为活性成分。

    4-하이드록시 타목시펜 유사체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 당뇨병 치료 또는 예방용 조성물
    12.
    发明公开
    4-하이드록시 타목시펜 유사체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 당뇨병 치료 또는 예방용 조성물 有权
    用于治疗或预防包含4-羟基酪氨酸类似物或药物可接受的作为有效成分的药物的糖尿病的组合物

    公开(公告)号:KR1020120073944A

    公开(公告)日:2012-07-05

    申请号:KR1020100135875

    申请日:2010-12-27

    Abstract: PURPOSE: A composition containing GSK5182 for preventing or treating diabetes is provided to suppress glucose generation gene expression and to lower glucose levels in blood. CONSTITUTION: A pharmaceutical composition for preventing or treating diabetes contains a 4-hydroxy tamoxifen derivative of chemical formula 1 or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition additionally contains a pharmaceutically acceptable carrier. The pharmaceutical composition reduces glucose levels in blood. A food composition for preventing or treating diabetes contains the derivative thereof or a sitologically acceptable salt thereof as an active ingredient.

    Abstract translation: 目的:提供含有GSK5182用于预防或治疗糖尿病的组合物,以抑制葡萄糖生成基因表达并降低血液中的葡萄糖水平。 构成:用于预防或治疗糖尿病的药物组合物含有化学式1的4-羟基他莫昔芬衍生物或其药学上可接受的盐作为活性成分。 药物组合物另外含有药学上可接受的载体。 药物组合物降低血液中的葡萄糖水平。 用于预防或治疗糖尿病的食品组合物含有其衍生物或作为有效成分的可以使用的盐。

Patent Agency Ranking