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    홍삼, 당귀, 진피 및 녹차의 생약 추출물을 함유하는 혈관 질환의 예방 또는 치료용 조성물
    12.
    发明公开
    홍삼, 당귀, 진피 및 녹차의 생약 추출물을 함유하는 혈관 질환의 예방 또는 치료용 조성물 有权
    组合物，包括红姜，安哥拉，西泮，绿茶叶用于治疗或预防血管疾病的草药提取物

    公开(公告)号：KR1020130098051A

    公开(公告)日：2013-09-04

    申请号：KR1020120019860

    申请日：2012-02-27

    Applicant: 충남대학교산학협력단

    Inventor： 강종성 ,  김영호 ,  명창선 ,  조정원

    IPC: A61K36/258 ,  A61K36/232 ,  A61K36/752 ,  A61P9/00

    Abstract: PURPOSE: A composition containing red ginseng, Angelica gigas, Aurantii nobilis pericarpium, and green tea for preventing or treating vascular diseases is provided to suppress platelet aggregation and to be used as a therapeutic agent for treating vascular diseases. CONSTITUTION: A composition for preventing or treating vascular diseases contains a crude drug extract containing red ginseng, Angelica gigas, Aurantii nobilis pericarpium, and green tea. Red ginseng, Angelica gigas, Aurantii nobilis pericarpium, and green tea are mixed in a ratio of 2-6:1-2:1:1. The crude drug extract is prepared using a solvent selected among water, an alcohol solution, and alcohol. The vascular diseases are selected among artherosclerosis, hypertension, angina pectrois, ischemic heart disease, complications after transluminal coronary angioplasty, cerebral infarction, cerebral hemorrhage, and stroke. [Reference numerals] (AA) Mixture, in which red ginseng, Angelica gigas, Aurantii nobilis pericarpium, and green tea are mixed in a ratio of 2-6:1-2:1:1, with an extract solvent of 5-15 times amount of the crude drug mixture; (BB) Step of obtaining a filtered solution by extracting and filtering the mixture of the crud drug mixture and the extract solvent at 40-120°C for 2-24 hours; (CC) Step of drying and performing confrication of the filtered solution

    Abstract translation: 目的：提供一种含有红参，当归，高粱，绿茶用于预防或治疗血管疾病的组合物，以抑制血小板聚集，并用作治疗血管疾病的治疗剂。 构成：用于预防或治疗血管疾病的组合物含有含有红参，当归，高粱和绿茶的生药提取物。 红参，当归，甘草，绿茶以2-6：1-2：1：1的比例混合。 使用选自水，醇溶液和醇中的溶剂制备生药提取物。 血管疾病选自动脉粥样硬化，高血压，心绞痛，缺血性心脏病，经腔冠状动脉成形术，脑梗死，脑出血和中风后并发症。 [AA]混合物，其中红参，当归，甘草，绿茶以2-6：1-2：1：1的比例混合，提取溶剂为5-15 次生产药物混合物的量; （BB）通过在40〜120℃下将原料药混合物和提取溶剂的混合物萃取并过滤2〜24小时得到过滤溶液的步骤; （CC）干燥和进行过滤溶液的制备步骤

    인디루빈-3'-모노심을 포함하는 항혈전용 조성물
    15.
    发明公开
    인디루빈-3'-모노심을 포함하는 항혈전용 조성물 审中-实审
    包含靛玉红-3'-单核细胞的止血专用组合物

    公开(公告)号：KR1020170081610A

    公开(公告)日：2017-07-12

    申请号：KR1020170083049

    申请日：2017-06-30

    Applicant: 충남대학교산학협력단

    Inventor： 명창선 ,  김영호 ,  장태수 ,  이정진

    IPC: A61K31/404 ,  A61K31/4025 ,  A23L33/10

    CPC classification number: A61K31/404 ,  A23L33/10 ,  A61K31/4025

    Abstract: 본발명은인디루빈-3'-모노심을포함하는항혈전용조성물및 혈전성혈관재협착증또는혈전성동맥경화증의예방또는치료용조성물에관한것이다. 또한, 상기인디루빈-3'-모노심은혈소판응집을저해하는효과가우수하여항혈전용조성물이나혈전성혈관재협착증또는혈전성동맥경화증의예방또는치료용조성물로유용하게사용될수 있다.

    Abstract translation: 本发明涉及的组合物和仅hanghyeol血栓seonghyeol管狭窄或血栓形成的性动脉粥样硬化的组合物的包含植物指示器鲁宾3'-单预防或治疗。 此外，指示器可以用于抑制血小板聚集的鲁宾3'-单种植优异的效果仅在hanghyeol组合物或血栓seonghyeol管狭窄或用于预防或治疗动脉血栓形成硬化组合物中有用。

    뮤라야폴린 에이 유도체를 유효성분으로 함유하는 혈관 질환의 치료 또는 예방용 조성물
    19.
    发明公开
    뮤라야폴린 에이 유도체를 유효성분으로 함유하는 혈관 질환의 치료 또는 예방용 조성물 有权
    包含MURRAYAFOLINE用于治疗或预防血管疾病的衍生物的组合物

    公开(公告)号：KR1020130026081A

    公开(公告)日：2013-03-13

    申请号：KR1020110089469

    申请日：2011-09-05

    Applicant: 충남대학교산학협력단

    Inventor： 송규용 ,  명창선 ,  김영호

    IPC: A61K31/403 ,  A61P9/12 ,  A61P9/10 ,  A61P9/00

    CPC classification number: A61K31/404 ,  Y10S514/822 ,  Y10S514/824

    Abstract: PURPOSE: A composition containing a murrayafoline A derivative is provided to suppress platelet aggregation, and to prevent or treat vascular diseases. CONSTITUTION: A composition for preventing or treating vascular diseases contains a compound of chemical formula 1. In chemical formula 1, R1 is independently selected among hydrogen, C1-C6 alkyl, formyl, C1-C6 alkylester, and carboxylic acid; R2 is independently selected among hydrogen, hydroxy, C1-C6 alkyl, or C1-C6 alkyloxy; and R4 is independently selected from hydrogen, C1-C6 alkyl, C2-C6 alkenyl, or C1-C6 alkylketone.

    Abstract translation: 目的：提供含有药物衍生物衍生物的组合物，以抑制血小板聚集，并预防或治疗血管疾病。 构成：用于预防或治疗血管疾病的组合物含有化学式1的化合物。在化学式1中，R 1独立地选自氢，C 1 -C 6烷基，甲酰基，C 1 -C 6烷基酯和羧酸; R2独立地选自氢，羟基，C1-C6烷基或C1-C6烷氧基; 和R 4独立地选自氢，C 1 -C 6烷基，C 2 -C 6烯基或C 1 -C 6烷基酮。

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