公开(公告)号：KR102092199B1

公开(公告)日：2020-03-23

申请号：KR1020180046635

申请日：2018-04-23

Applicant: 충남대학교산학협력단

Inventor： 나정효 ,  이민형 ,  이솔

IPC: B01D39/16

公开(公告)号：KR1020100052008A

公开(公告)日：2010-05-19

申请号：KR1020080110851

申请日：2008-11-10

Applicant: 한양대학교 산학협력단 ,  충남대학교산학협력단

Inventor： 이민형 ,  최준식 ,  김현아

IPC: A61K47/48 ,  A61P29/00

CPC classification number: A61K47/50 ,  A61K48/00 ,  Y10S514/886

Abstract: PURPOSE: A vector containing anionic polymer for treating non-viral inflammatory diseases is provided to improved gene treatment efficiency. CONSTITUTION: An anti-inflammatory vector for treating inflammatory disease contains anti-inflammatory glucocorticoid and anionic polymer. The anionic polymer is polyethyleneimine. The molecular weight of polyethyleneimine is 5kDa. The anti-inflammatory glucocorticoid is hydrocortisone, dexamethesone, betamethasone, prednisone, prednisolone, triamcinolone, beclomethasone, or cortisonacetate. An anti-inflammatory vector for treating flammatory diseases contains the vector and gene.

Abstract translation: 目的：提供含有用于治疗非病毒性炎性疾病的阴离子聚合物的载体，以改善基因治疗效率。 构成：用于治疗炎性疾病的抗炎药物含有抗炎糖皮质激素和阴离子聚合物。 阴离子聚合物是聚乙烯亚胺。 聚乙烯亚胺的分子量为5kDa。 抗炎糖皮质激素是氢化可的松，地塞米松，倍他米松，泼尼松，泼尼松龙，曲安奈德，倍氯米松或醋酸钙。 用于治疗炎性疾病的抗炎药物含有载体和基因。