Abstract:
PURPOSE: A composition containing a water extract of Pleurotus eryngii var. ferulea (Pf.) as an active ingredient is provided to suppress absorption of cholesterol and neutral fat in body, and to prevent or treat hyperlipidemia. CONSTITUTION: A composition for preventing or treating hyperlipidemia contains a water extract of Pleurotus eryngii var. ferulea (Pf.) as an active ingredient. The water extract is prepared by extracting Pleurotus eryngii var. ferulea (Pf.) at 20-60 deg. C for 12-36 hours. The extract is prepared from 1-5g of Pleurotus eryngii var. ferulea (Pf.) powder with 50 mL of water. A pharmaceutical composition for preventing or treating hyperlipidemia contains the water extract as an active ingredient. A health functional health food supplement composition for treating hyperlipidemia contains the water extract as an active ingredient. [Reference numerals] (AA) Cholesterol esterase activity
Abstract:
PURPOSE: A water extract of Laetiporus sulphureus var. miniatus (Jungh.) Imaz. is provided to suppress absorption of cholesterol and neutral fat in body, and to prevent or treat hyperlipidemia. CONSTITUTION: A composition for preventing or treating hyperlipidemia contains a water extract of Laetiporus sulphureus var. miniatus (Jungh.) Imaz. as an active ingredient. A pharmaceutical product for preventing or treating hyperlipidemia contains the water extract as an active ingredient. A health function food for preventing or treating hyperlipidemia contains the water extract as an active ingredient. The health functional food is a food, a food additive, or a drink. The health functional food suppresses absorption of cholesterol and/or neutral fat. A method for preventing or treating hyperlipidemia comprises a step of administering the water extract to animals exclusive human. [Reference numerals] (AA) CEL inhibition%; (BB) Water extract; (CC) Ethanol extract
Abstract:
PURPOSE: A composition containing an alcohol extract of Albatrellus dispansus is provided to suppress cholesterol and neutral fat absorption, and to prevent or treat hyperlipidemia. CONSTITUTION: A composition for preventing or treating hyperlipidemia contains a C1-C10 alcohol extract of Albatrellus dispansus as an active ingredient. A pharmaceutical product for preventing or treating hyperlipidemia contains the extract as an active ingredient. A health functional food for preventing or treating hyperlipidemia contains the extract as an active ingredient. A method for preventing or treating hyperlipidemia comprises a step of administering the extract to animals exclusive of human. The extract suppresses blood cholesterol and/or neutral fat absorption. [Reference numerals] (AA) CEL activity inhibition(%); (BB) Water extract (Comparative example); (CC) Ethanol extract
Abstract:
A polypeptide comprising a W-rich peptide is provided to be useful for inhibiting formyl peptide receptor(FPR)-based receptor activity, thereby being used for preventing and treating inflammation and auto-immune diseases. The polypeptide comprises a W-rich peptide and a conservative variant or functional fragment thereof, consists of 4 to 15 numbers of amino acids long and is represented by SEQ ID NOS: 4, 5, 6, 8, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34 or 35. The method for treating arthritis, auto-immune diseases or Alzheimer's Disease in a subject comprises the steps of providing the subject in need with the polypeptide or a W-rich peptide mimic thereof of effective amount for preventing an inflammation.
Abstract translation:提供包含富含W的肽的多肽可用于抑制基于甲酰基肽受体(FPR)的受体活性,从而用于预防和治疗炎症和自身免疫疾病。 多肽包含富含W的肽及其保守变体或功能片段,其长度为4至15个氨基酸数,并由SEQ ID NO:4,5,6,8,12,13,14,15 ,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34或35.用于治疗关节炎,自身免疫的方法 疾病或阿尔茨海默病包括以下步骤:向有需要的受试者提供有效量的多肽或其富含W的肽模拟物以防止炎症。
Abstract:
PURPOSE: A composition containing a water extract of Fomitella fraxinea(Fr.)Imaz. is provided to suppress absorption of neutral fat and cholesterol, and to prevent or treat obesity. CONSTITUTION: A composition for preventing or treating obesity contains a water extract of Fomitella fraxinea(Fr.)Imaz. as an active ingredient. Health functional food for preventing or treating obesity contains the water extract as an active ingredient. The health functional food is food, a food additive, or a drink. The health functional food and the water extract suppress the activity of lipase and/or pancreatic cholesterol esterase. [Reference numerals] (AA) TGL activity inhibition(%); (BB) Water extract; (CC) (Comparative example) Ethanol extract
Abstract:
PURPOSE: A composition containing an alcohol extract of Hapalopilus rutilans is provided to suppress digestion and absorption of body fat, and to prevent or treat obesity. CONSTITUTION: A composition for preventing or treating obesity contains a C1-C10 alcohol extract of Hapalopilus rutilans as an active ingredient. The extract is prepared by extracting Hapalopilus rutilans with 90-99.9%(v/v) ethanol at 20-60 deg. C for 12-36 hours. A pharmaceutical product for preventing or treating obesity contains the extract as an active ingredient. A health functional food for preventing or treating obesity contains the extract as an active ingredient. A method for preventing or treating obesity comprises a step of administering the extract to animals exclusive of human. The extract suppresses activation of pancreatic lipase. [Reference numerals] (AA) TGL activity inhibition(%); (BB) Water extract (Comparative example); (CC) Ethanol extract