Abstract:
형광물질을이용하여미생물을구별하는방법및 상기미생물검출용조성물및 키트를제공한다. 일구체예에따르면, 상기미생물을구별하는방법, 미생물검출용조성물및 키트는형광물질에결합하는단백질패턴을비교하여여러미생물을구별하므로, 쉽고빠르며정확한동정결과를제공할수 있다. 또한, 상기단백질패턴을형광바코드형태로제공하여신속하고정확한미생물동정을제공할수 있다.
Abstract:
본발명은단실유도체의새로운용도에대한것으로, 구체적으로단실유도체가살아있는세포를이미징하는데유용하게활용될수 있음을밝힌것이다. 본발명의제조방법및 이를통해제조된다양한단실유도체는세포와접촉시세포내에위치하므로, 이를통하여세포이미징에유용하게활용될수 있다. 따라서, 이러한분자는살아있는세포의이미징을가능하게하므로, 다양한연구및 산업적인용도로활용될수 있다.
Abstract:
본 발명은 형광 화합물을 이용하여 헤파티티스 C 바이러스가 감염된 간세포와 정상세포를 구별하는 방법에 관한 것이다. 일 구체예에 따르면, 본 발명의 방법은 (E)-2-((2E,4E)-5-(1-에틸-3,3-디메틸-5-술포-3H-인돌-1-이움-2-일)펜타-2,4-디엔-1-일이덴)-3,3-디메틸-1-(8-옥소-8-((2-(비닐술포닐)에틸)아미노)옥틸)인돌린-5-술포네이트에 결합하는 단백질 패턴을 비교하여 헤파티티스 C 바이러스가 감염된 간세포와 정상세포를 구별하므로, 쉽고 빠르며 정확한 동정 결과를 제공할 수 있다.
Abstract:
The present invention relates to a kit for detecting Escherichia coli, containing fluorescent compounds which specifically bind to pyruvate formate-lyase activating enzyme expressed from ybiY gene of Escherichia coli and a method for detecting Escherichia coli using the same. According to a specific example, the method and the kit easily, quickly, and accurately provide identification results by detecting pyruvate formate-lyase activating enzyme expressed from ybiY gene of Escherichia coli which specifically binds to 3',6'-bis(acetyl oxy)-5-(chloromethyl)-spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one and distinguishing Escherichia coli and Enterococcus faecalis.
Abstract:
The present invention relates to a kit for detecting Enterobacter cloacae, containing fluorescent compounds which specifically bind to formate hydrogen lyase expressed from hycB gene of Enterobacter cloacae and a method for detecting Enterobacter cloacae using the same. According to a specific example, the method and the kit of the present invention easily, quickly, and accurately provide identification results by detecting formate hydrogen lyase expressed from hycB gene of Enterobacter cloacae and distinguishing Enterobacter cloacae and Escherichia coli.
Abstract:
The present invention relates to a kit for detecting Bacillus subtilis, containing fluorescent compounds which specifically bind to pyridoxine kinase which is expressed from thiD gene of Bacillus subtilis and a method for detecting Bacillus subtilis using the same. According to a specific example, the method and the kit easily, quickly, and accurately provide identification results by detecting pyridoxine kinase expressed from thidD gene of Bacillus subtilis, which specifically binds to 3',6'-bis(acetyloxy)-5-(chlromethyl)-spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one and distinguishing Bacillus subtilis and Bacillus cereus.
Abstract:
The present invention relates to a method for distinguishing hepatitis C virus injected liver cells and normal cells using fluorescent compounds. According to a specific example, the method easily, quickly, and accurately provides identification result by comparing the pattern of proteins which are conjugated to 2-(6-hydroxy-3-oxo-3H-xanthene-9-yl)-5-((2-(vinylsulfonyl)ethyl)carbamoyl)benzoic acid and 2-(6-hydroxy-3-oxo-3H-xanthene-9-yl)-4-((2-(vinylsulfonyl)ethyl)carbamoyl)benzoic acid and distinguishing hepatitis C virus infected liver cells and normal cells.