公开(公告)号：KR100810533B1

公开(公告)日：2008-03-10

申请号：KR1020060112321

申请日：2006-11-14

Applicant: 한국식품연구원

Inventor： 김종태 ,  김양하 ,  김철진 ,  조용진 ,  최애진 ,  이막순

IPC: A61K36/21 ,  A61P3/04

Abstract: An extract of Portulaca oleracea is provided to inhibit fat accumulation, decompose the fat and show excellent HSL(hormone sensitive lipase) gene expression effect, thereby being applied as a health functional food or a medicine for anti-obesity. An anti-obese composition comprises an extract of Portulaca oleracea obtained by using an organic solvent such as methanol and ethanol. A method for preparing an anti-obese composition comprises the steps of: (a) breaking down a cell wall of the Portulaca oleracea through high pressure and high temperature treatment in an extrusion molding device, wet ultrasonic wave treatment, high temperature and high pressure steaming treatment or pressurization treatment to water-solubilize the cell wall of the Portulaca oleracea; and (b) adding methanol or ethanol to the water-solubilized Portulaca oleracea to obtain an extract of the Portulaca oleracea. A pharmaceutical composition for anti-obesity comprises the extract of the Portulaca oleracea as an effective ingredient.

Abstract translation: 提供马齿苋提取物以抑制脂肪堆积，分解脂肪并显示优异的HSL（激素敏感性脂肪酶）基因表达效应，从而作为健康功能食品或抗肥胖药物。 抗肥胖组合物包含通过使用有机溶剂如甲醇和乙醇获得的马齿苋提取物。 制备抗肥胖组合物的方法包括以下步骤：（a）通过挤压成型装置中的高压高温处理，湿法超声波处理，高温高压蒸煮，分解马齿苋的细胞壁 治疗或加压处理以对马齿苋的细胞壁进行水溶解; 和（b）向水溶性的马齿苋中加入甲醇或乙醇以获得马齿苋的提取物。 用于抗肥胖的药物组合物包含马齿苋提取物作为有效成分。