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公开(公告)号:US10017461B2
公开(公告)日:2018-07-10
申请号:US15485636
申请日:2017-04-12
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Catherine A. Bothof , Yi He , Jerald K. Rasmussen , Kannan Seshadri , Clinton P. Waller, Jr. , Douglas E. Weiss
IPC: C07C279/10 , C07C279/12 , C08F259/08 , C08F283/04 , C08J7/18 , B01J20/285
CPC classification number: C07C279/12 , B01D39/1676 , B01J20/285 , C07C277/08 , C07C279/14 , C07C281/16 , C07K1/34 , C08F259/08 , C08F283/04 , C08G69/48 , C08J7/18 , C08J9/283 , C08J9/42 , C08J2327/16 , C08J2377/00 , C12N7/00 , Y02C10/08 , Y10T428/31855
Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
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公开(公告)号:US20170240591A1
公开(公告)日:2017-08-24
申请号:US15591490
申请日:2017-05-10
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Jerald K. Rasmussen , Kannan Seshadri , Robert T. Fitzsimons, JR. , James I. Hembre , Catherine A. Bothof , Erin A. Satterwhite , George W. Griesgraber , Yi He , Louis C. Haddad
IPC: C07K1/14 , B01D21/01 , C08F126/02 , C08F120/60 , C12N11/08 , C08G73/02
CPC classification number: C07K1/14 , B01D21/01 , C08F120/60 , C08F126/02 , C08G69/10 , C08G73/0206 , C08G73/022 , C08G73/028 , C08L77/04 , C08L79/02 , C08L83/08 , C12N7/02 , C12N11/08 , G01N33/54393 , G01N33/545 , Y10T428/249978 , Y10T428/249991 , Y10T428/2935 , Y10T428/2998 , Y10T442/20
Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
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公开(公告)号:US09616394B2
公开(公告)日:2017-04-11
申请号:US14400810
申请日:2013-05-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Catherine A. Bothof , George W. Griesgraber , James I. Hembre , Jerald K. Rasmussen
IPC: B01D71/78 , B01D71/56 , B01D71/40 , B01D71/76 , C09D179/02 , G01N33/543 , C09D177/04 , C08F255/02 , C08G69/48 , B01J20/32 , C08G69/10 , C08G73/02
CPC classification number: B01D71/78 , B01D71/40 , B01D71/56 , B01D71/76 , B01D2323/30 , B01D2323/385 , B01D2325/12 , B01J20/261 , B01J20/264 , B01J20/321 , B01J20/3282 , B01J20/3293 , B01J20/3297 , C08F255/02 , C08F283/04 , C08G69/10 , C08G69/48 , C08G73/0206 , C08G73/022 , C08G73/028 , C08J7/18 , C08J2323/06 , C08J2323/12 , C08J2377/00 , C08J2433/14 , C09D177/04 , C09D179/02 , G01N33/54393 , G01N33/545
Abstract: Guanidinyl ligand-functionalized polymers, methods of making the same, and substrates bearing a grafted coating of the ligand-functional polymers are described. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, endotoxins and proteins, at pH's near or below the pI's of the biomaterials.
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公开(公告)号:US20160339412A1
公开(公告)日:2016-11-24
申请号:US15228469
申请日:2016-08-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Jerald K. Rasmussen , Catherine A. Bothof
IPC: B01J20/26 , C09D5/00 , C09D4/00 , C07K1/22 , B01J20/32 , C07K14/765 , C07K16/00 , C09D133/24 , C09D179/02
CPC classification number: B01J20/267 , B01J20/289 , B01J20/3212 , B01J20/3219 , B01J20/327 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , C07K1/22 , C07K14/765 , C07K16/00 , C08G73/02 , C08J7/047 , C08J7/18 , C08J2333/24 , C08J2377/06 , C08J2433/14 , C08J2433/24 , C09D4/00 , C09D5/002 , C09D133/24 , C09D179/02 , G01N33/54393
Abstract: Ligand-functionalized substrates are describe that are useful in selectively binding and removing biological materials from biological samples, and methods for preparing the same.
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公开(公告)号:US20150203645A1
公开(公告)日:2015-07-23
申请号:US14415862
申请日:2013-09-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Jerald K. Rasmussen , Catherine A. Bothof
IPC: C08J7/18 , C07K16/00 , C07K14/765 , C08J7/04 , C07K1/22
CPC classification number: B01J20/267 , B01J20/289 , B01J20/3212 , B01J20/3219 , B01J20/327 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , C07K1/22 , C07K14/765 , C07K16/00 , C08G73/02 , C08J7/047 , C08J7/18 , C08J2333/24 , C08J2377/06 , C08J2433/14 , C08J2433/24 , C09D4/00 , C09D5/002 , C09D133/24 , C09D179/02 , G01N33/54393
Abstract: Ligand-functionalized substrates are describe that are useful in selectively binding and removing biological materials from biological samples, and methods for preparing the same.
Abstract translation: 描述了可用于选择性结合和从生物样品中除去生物材料的配体官能化底物及其制备方法。
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公开(公告)号:US20150166703A1
公开(公告)日:2015-06-18
申请号:US14600117
申请日:2015-01-20
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Jerald K. Rasmussen , Catherine A. Bothof , Kannan Seshadri , Erin A. Satterwhite , Robert T. Fitzsimons, JR. , James L. Hembre , Mahfuza B. Ali
IPC: C08F220/56
CPC classification number: C08F220/56 , B01D15/00 , C08F20/00 , C08F26/02 , C08F220/60 , G01N33/54393 , Y10T428/12264 , Y10T428/249991
Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
Abstract translation: 配体功能化底物,制备配体官能化底物的方法,以及使用官能化底物的方法。
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公开(公告)号:US20140228457A1
公开(公告)日:2014-08-14
申请号:US14254247
申请日:2014-04-16
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Simon K. Shannon , Catherine A. Bothof , Babu N. Gaddam , Jerald K. Rasmussen , Richard B. Ross
IPC: C08F271/02 , B01J41/14 , B01J39/20
CPC classification number: C07K17/08 , B01D15/08 , B01D15/3804 , B01D15/3809 , B01J20/264 , B01J20/286 , B01J20/287 , B01J20/3204 , B01J20/3208 , B01J20/3219 , B01J20/3242 , B01J20/3255 , B01J20/3276 , B01J20/3278 , B01J20/328 , B01J39/17 , B01J39/18 , B01J39/20 , B01J41/12 , B01J41/14 , B01J2220/52 , B01J2220/54 , B01J2220/58 , B01J2220/62 , C07K1/22 , C08F271/02
Abstract: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.
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公开(公告)号:US20130224825A1
公开(公告)日:2013-08-29
申请号:US13848336
申请日:2013-03-21
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Jerald K. Rasmussen , Kannan Seshadri , Robert T. Fitzsimons, JR. , James I. Hembre , Catherine A. Bothof , Erin A. Satterwhite , George W. Griesgraber , Yi He , Louis C. Haddad
CPC classification number: C07K1/14 , B01D21/01 , C08F120/60 , C08F126/02 , C08G69/10 , C08G73/0206 , C08G73/022 , C08G73/028 , C08L77/04 , C08L79/02 , C08L83/08 , C12N7/02 , C12N11/08 , G01N33/54393 , G01N33/545 , Y10T428/249978 , Y10T428/249991 , Y10T428/2935 , Y10T428/2998 , Y10T442/20
Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
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公开(公告)号:US20220120649A1
公开(公告)日:2022-04-21
申请号:US17562459
申请日:2021-12-27
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Jerald K. Rasmussen , Catherine A. Bothof , George W. Griesgraber , Semra Colak Atan , James I. Hembre , Robert T. Fitzsimons, JR.
IPC: G01N1/40 , B01D71/44 , C07K1/34 , C08J7/18 , C07F9/38 , G01N33/544 , C07K1/18 , B01D67/00 , B01D71/52 , B01D71/56 , B01J20/26 , B01J20/28 , B01J20/32 , C07F5/00 , C07F5/02 , C07F5/04
Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
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公开(公告)号:US11279731B2
公开(公告)日:2022-03-22
申请号:US16174373
申请日:2018-10-30
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Jerald K. Rasmussen , Catherine A. Bothof , Kannan Seshadri , James I. Hembre , Robert T. Fitzsimons, Jr. , George W. Griesgraber , Yi He
IPC: C07K1/22 , B01D71/56 , C09D179/02 , B01D67/00 , C07H1/08 , C07K14/765
Abstract: A substrate comprising a crosslinked polymer primer layer, and grafted thereto a ligand-functionalized polymer is provided. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, and proteins, at pH's near or below the pI's of the biomaterials.
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