公开(公告)号：EP0802920A2

公开(公告)日：1997-10-29

申请号：EP96903378.0

申请日：1996-01-03

Applicant: Abbott Laboratories

Inventor： ALDER, Lisa, A. ,  BURRES, Neal, S. ,  HOCHLOWSKI, Jill, E. ,  JACKSON, Marianna ,  McALPINE, James, B. ,  KLEIN, Larry, L. ,  LARTEY, Paul, A. ,  YEUNG, Clinton

IPC: C12P17 ,  A01N43 ,  A61K31 ,  A61P31 ,  C07H15 ,  C07H17 ,  C12R1

CPC classification number: C07H15/10 ,  A01N43/16

Abstract: Novel antifungal agents having formula (I), wherein R is hydrogen or -C(O)-R1 wherein R1 is alkenyl, C2-C12-alkyl, aryl, arylalkenyl, arylalkyl, aryl-aryl-, arylalkoxy-aryl-, aryloxyl-aryl-, aryl-aryl-aryl- or arylalkoxy-aryl-aryl-, or pharmaceutically acceptable salts, esters or prodrugs thereof, as well as (i) pharmaceutical compositions comprising such compounds, (ii) methods of treatment using such compounds, and (iv) methods and fungal cultures useful in making the same.