公开(公告)号：JP2004028962A

公开(公告)日：2004-01-29

申请号：JP2002189735

申请日：2002-06-28

Applicant: Aloka Co Ltd ,  アロカ株式会社

Inventor： SUZUKI KATSUHIRO ,  MATSUDA TORU ,  IDA TAIDO ,  FUJIKI KUNIHIRO

IPC: G01N35/02

Abstract: PROBLEM TO BE SOLVED: To provide a specimen analyzer for preventing occurrence of adverse effects from such a factor as lowered analysis accuracy or disabled analysis caused by a claw of a manipulator with a specimen container gripped therein overlapping with a position to be analyzed.
SOLUTION: A blood serum amount estimation device 1 selects a position to be analyzed from regions not covered by a bar-code label 200 on an outer circumferential surface of a blood collection tube 100 based on positional information on the label 200 detected by a glossiness sensor 14. When the claw 211 of the manipulator 21 is determined to overlap with the selected position to be analyzed, the collection tube 100 is once returned to a blood collection tube rack 600 and the rotating position of the manipulator 21 relative to the collection tube 100 is adjusted by actuating a manipulator rotating mechanism 22 so as not to overlap the claw 211 with the position to be analyzed, then the collection tube 100 is re-gripped by the manipulator 21.
COPYRIGHT: (C)2004,JPO

公开(公告)号：JPH1123472A

公开(公告)日：1999-01-29

申请号：JP18224697

申请日：1997-07-08

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01N33/483 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To enable an accurate inspection by adding a luminescent reagent into a plurality of specimen containers into which different indication reagents are introduced, detecting luminescence, determining the presence or absence of luminescence, and determining the property of a sample from the combination of luminescence. SOLUTION: In a fractionating unit 10, each fractionating pump 24 sucks a luminescent reagent from each luminescent reagent tank 28 and supplies it to a nozzle 20 via a fractionation control part 30. In a light detecting unit 12, a reagent and a DNA sample as a child specimen are introduced into each well 8, and a luminescent reagent is additionally introduced into each well 8 for inspecting the presence or absence of the reaction of an indication reagent by luminescence in each container. A photodetector 32 detects light in the wells 8 and outputs a photodetection signal 34 responsive to the amount of received light, and the results of photodetection are stored in a data processing part 38 via signal processing part 36. In a data processing unit 14, the results of photodetection in the data processing part 38 are matched with determining conditions stored in a determining condition table 40 to determine the type of the human leucocyte antigen of the specimen.

公开(公告)号：JPH10206212A

公开(公告)日：1998-08-07

申请号：JP747297

申请日：1997-01-20

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01F23/28 ,  G01N35/10

Abstract: PROBLEM TO BE SOLVED: To eliminate a positional shift in a light quantity characteristic by operating a difference while shifting a transmission light quantity characteristic stepwise to another transmission light quantity characteristic in the longitudinal direction, and detecting a true difference characteristic among a plurality of difference characteristics wherein a first and a second light quantity characteristics are registered properly. SOLUTION: A fresh nozzle chip 10 is set to a nozzle base part 12. Then, a first transmission light quantity characteristic is stored in a memory part 24 via a control part 18. After a sample is sucked, a second transmission light quantity characteristic is taken and stored in the memory part 24. After two transmission light quantities are registered and a zero point is specified, one transmission light quantity characteristic is shifted to the other transmission light quantity characteristic, and a difference is operated as a difference characteristic. Particularly, a square sum of the difference of two characteristics is operated. After all difference characteristics and square sums are operated, a shift amount of a minimum square sum is specified and used as a true difference characteristic with no positional shift. A liquid column height is obtained in this manner.

公开(公告)号：JPH08320317A

公开(公告)日：1996-12-03

申请号：JP12803695

申请日：1995-05-26

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01N33/48 ,  A61B5/154 ,  A61B5/14

Abstract: PURPOSE: To obtain a sampling apparatus by which a blood sample can be sampled safely and surely without removing a sealing stopper from a blood sampling tube after a centrifugal separation. CONSTITUTION: A couple base 10 can be freely raised and lowered, and a coupler 12 is mounted on the coupler base 10. A blood sampling tube 14 is inserted into the coupler 12 in an inverted state, and a sampling needle 26 is pierced through a rubber stopper 24. A packing 38 is used to seal a part between the coupler base 10 and the coupler 12 and to seal a part between a sampling container 16 and the coupler base 10. When they are sealed, they are pressed to the lower part from the upper part with reference to the blood sampling tube 14. The interior of the blood sampling container 16 is sucked and opened to the air repeatedly, and a serum 22 is pulled out without pressurizing the interior of the blood sampling tube 14.

公开(公告)号：JPH07218513A

公开(公告)日：1995-08-18

申请号：JP1064994

申请日：1994-02-01

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU ,  KATOU YUUKO

IPC: G01N1/00 ,  G01N35/10

Abstract: PURPOSE:To effectively clean a nozzle after sample collection. CONSTITUTION:The tip end of a nozzle part 10 which is a dual-tube nozzle is inserted into a well 88. When a cleaning liquor 50 is supplied from a divergence route 46 and an air 204 is supplied at the same time, air bubbles are generated at a junction point, and the inside of an internal nozzle and an inter- nozzle route 54 are cleaned by means of the cleaning liquor including the air bubbles. During the cleaning, vacuum suction is executed for the inter-nozzle route 54, and vertical movement of the internal nozzle 14 is repeatedly executed.

公开(公告)号：JPH0755819A

公开(公告)日：1995-03-03

申请号：JP20353393

申请日：1993-08-18

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01F23/14 ,  G01N35/10

Abstract: PURPOSE:To allow detection of liquid level even in an enclosed system without generating bubbles by providing a nozzle tip for sucking and delivering a liquid sample, a sensor for detecting the pressure in an air hose, etc. CONSTITUTION:When the air is sucked or delivered into or from a tip 36 by means of a cylinder 46, a resistance is generated in an air hose 44 and the tip 36 when the air passes through them. The resistance is detected by a pressure sensor 54 in the form of a variation of inner pressure within the air hose 54. The tip 36 is then lowered while sucking and delivering the air and the like and the liquid level is detected when the inner pressure varies significantly. When the inner pressure varies abruptly down to a negative level, the tip 36 is blocked at the end thereof and then a control section 84 makes a decision that the liquid level is reached and stops suction/delivery and lowering of the tip 36. This constitution allows to finish detection of liquid level prior to generation of bubbles on the liquid level while eliminating the need of sampling the inner pressure of the air hose 44 or the comparison of the inner pressure with a reference value.

公开(公告)号：JPH0727663A

公开(公告)日：1995-01-31

申请号：JP17548193

申请日：1993-07-15

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01M3/38 ,  G01M3/02 ,  G01N35/00 ,  G01N35/10

Abstract: PURPOSE:To provide a method for detecting the presence or absence of liquid leakage constantly on dispensing and its dispensing device. CONSTITUTION:The dispensing device forms light beams 20 by a near infrared light-emitting diode 14, a lens 16 for converting injected near infrared rays to parallel light beams, and a cylindrical lens 18 for constricting the parallel light beams to a size in the axial direction of a chip 36, and the light beams 20 has a beam width which is wider than the width of the axis of the chip 36. Therefore, when one part of a specimen 12 drops as a liquid ball from the tip of the chip 36, the liquid ball and the light beams 20 always cross each other. Then, a liquid leakage detection circuit 26 inputs the quantity of constant transmission light when the chip 36 moves via an optical filter 22 and a photo detector 24 at a light reception part and then outputs the signal of 'Liquid leakage occurrence' on a monitor 28 when it detects a rapid change in the level of quantity of transmission light and also displays a message indicating liquid leakage and gives a warning.

公开(公告)号：JP2011078881A

公开(公告)日：2011-04-21

申请号：JP2009231810

申请日：2009-10-05

Applicant: Aloka Co Ltd ,  アロカ株式会社

Inventor： TAKASU TATSUYA ,  SATO TAKASHI ,  OZAWA YUKIKO ,  OGAWA KOJI ,  MATSUDA TORU

IPC: B08B3/02 ,  B08B3/04 ,  B08B11/00 ,  G01N35/10

Abstract: PROBLEM TO BE SOLVED: To provide a nozzle cleaning unit capable of cleaning a nozzle with higher efficiency. SOLUTION: The nozzle cleaning unit 20 mounted on a dispensing apparatus includes a cleaning vessel 22, a cleaning solution sprayer 44 spraying a cleaning solution in the cleaning vessel 22, a drying sprayer 50 spraying air to blow away the cleaning solution adhered to the nozzle into the cleaning vessel 22, a moving mechanism causing the nozzle 12 to ascend and descend and a controller controlling those units. The controller repeats, at least twice, a set operation consisting of a cleaning process of spraying the cleaning solution while causing the nozzle 12 to descend and a drying process of spraying air while causing the nozzle 12 to ascend, after the cleaning process. COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供一种能够以更高效率清洗喷嘴的喷嘴清洁单元。

解决方案：安装在分配装置上的喷嘴清洁单元20包括清洁容器22，将清洁溶液喷射在清洁容器22中的清洁溶液喷雾器44，喷雾空气以吹扫附着到 喷嘴进入清洁容器22，使喷嘴12上升和下降的移动机构和控制这些单元的控制器。 在清洁过程之后，控制器重复至少两次，该操作包括在使喷嘴12下降的同时喷射清洁溶液的清洁过程和喷雾空气的同时使喷嘴12上升的干燥过程。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2010025804A

公开(公告)日：2010-02-04

申请号：JP2008188717

申请日：2008-07-22

Applicant: Aloka Co Ltd ,  アロカ株式会社

Inventor： OGAWA KOJI ,  SATO TAKASHI ,  TAKASU TATSUYA ,  MATSUDA TORU ,  OZAWA YUKIKO

IPC: G01N35/10 ,  G01N1/00

Abstract: PROBLEM TO BE SOLVED: To provide a nozzle unit capable of more certainly performing proper suction/discharge treatment. SOLUTION: The nozzle unit 10 mounted on a dispenser has a pipe 64 of which the leading end 90 is sharply formed and which has a double pipe structure keeping a liquid passage 80 and an air passage 84 sequentially arranged thereto from the inside in a concentric circular state. The liquid passage 80 is bent by almost 90° at the position slightly near to the rear end of the leading end 90 and a liquid suction and discharge port 82 is formed to the side surface of the pipe 64. Further, the air passage 84 communicates with the air suction and discharge port 86 provided in the side surface of the pipe 64 at the position in the vicinity of the rear end of the liquid suction and discharge port 82. Viewed from another angle, the leading end 90 of the pipe 64 is formed into a solid conical shape having no opening formed thereto. By this arrangement, even if the nozzle unit 10 pierces the plug body of a container, no cut refuse is produced and, as a result, proper suction/discharge treatment can be performed. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供能够更可靠地执行适当的吸入/排出处理的喷嘴单元。 解决方案：安装在分配器上的喷嘴单元10具有尖端90被尖锐地形成的管64，并且具有保持液体通道80和空气通道84的双重管道结构， 同心圆形状态。 液体通道80在稍微靠近前端90的后端的位置处弯曲几乎90°，并且在管64的侧表面上形成液体吸入和排出口82.另外，空气通道84连通 在排出口82的后端附近位于配管64的侧面设置有吸气排出口86.从另一角度看，管64的前端90为 形成为没有形成开口的固体圆锥形状。 通过这种布置，即使喷嘴单元10刺穿容器的塞体，也不产生切屑，结果可以进行适当的抽吸/排出处理。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2004037322A

公开(公告)日：2004-02-05

申请号：JP2002196434

申请日：2002-07-04

Applicant: Aloka Co Ltd ,  アロカ株式会社

Inventor： SUZUKI KATSUHIRO ,  MATSUDA TORU ,  KAWANABE JUNICHI ,  KUMAZAWA HIROKI

IPC: G01F23/28 ,  G01F23/292 ,  G01N21/35 ,  G01N21/3577 ,  G01N21/359 ,  G01N33/48 ,  G01N33/49

Abstract: PROBLEM TO BE SOLVED: To provide a specimen analyzing apparatus which can accurately and surely analyze a specimen (e.g., estimation of an amount of serum, etc.) even when an information carrying label is, for example, adhered to a specimen container. SOLUTION: An amount-of-serum estimating apparatus 1 obtains data of a differentiated value obtained by linearly differentiating a profile by forming the profile of an intensity of a transmitted ray based on a detected result by detecting a transmitted light by a line sensor 12 when a blood collecting tube 100 is irradiated with an infrared ray from an infrared ray surface source 11 by changing amounts of the ray at two stages. The estimating apparatus 1 specifies positions of an upper end and a lower end of a bar code label 200 based on data of the differentiated value, uses the two data of the differentiated values by changing in a region in which the label 200 is present and a region in which the label 200 is not present, specifies positions of an interface between an upper liquid surface of the serum layer of the blood specimen in the tube 100 and a separation layer, and estimates the amount of the serum in the tube 100 based on their positions and a shape of the tube 100. COPYRIGHT: (C)2004,JPO