公开(公告)号：DE19503327A1

公开(公告)日：1996-08-08

申请号：DE19503327

申请日：1995-02-02

Applicant: BASF AG

Inventor： EBEL KLAUS DR ,  EIERMANN MATTHIAS DR ,  PAPKALLA THOMAS DR

IPC: C07C67/333 ,  C07C69/738

Abstract: Prepn. of 5-oxo-6-heptenoic acid alkyl esters of formula (I) comprises: (a) reaction of 5-acetyl-2-norbornene (VI) with a dialkylcarbonate of formula (VII), in the presence of a base, to give a 3-(2-norbornen-5-yl)-3-oxopropionic acid alkyl ester of formula (II); (b) reaction of (II) with an unsatd. cpd. of formula (III) in the presence of a base, and hydrolysis to give a 5-(2-norbornen-5-yl)-5- oxopentanoic acid of formula (IV); (c) esterification to a 5-(2-norbornen-5-yl)-5- oxopentanoic acid ester of formula (V); and (d) thermal cleavage of this cpd. at 300-700 degrees C to give (I). Q = H (in (IV)) or R (in (V)); X, Y = H or Me; R = 1-8C alkyl; R = 1-4C alkyl; Z = CN or CO2R ; R = 1-4C alkyl;