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11.
公开(公告)号:DE3532133A1
公开(公告)日:1987-03-12
申请号:DE3532133
申请日:1985-09-10
Applicant: BASF AG
Inventor: BLOHM DIETMAR DR , MARTIN CHRISTOPH DR , HILLEN HEINZ DR , MARCINOWSKI STEFAN DR
Abstract: Process for the preparation of proteins by cultivation of optionally genetically manipulated prokaryotic microorganisms and isolating the desired protein from the biomass, wherein the desired protein is defined at the N-terminal end with respect to the presence or absence of the amino acid methionine by carrying out the cultivation in the presence of a defined concentration of manganese ions or other heavy metal ions.
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公开(公告)号:DE3266373D1
公开(公告)日:1985-10-24
申请号:DE3266373
申请日:1982-06-25
Applicant: BASF AG
Inventor: COOPER BRYAN DR , KUESTERS WERNER DR , MARTIN CHRISTOPH DR , SIEGEL HARDO DR
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公开(公告)号:DE3260536D1
公开(公告)日:1984-09-13
申请号:DE3260536
申请日:1982-05-19
Applicant: BASF AG
Inventor: GRAMLICH WALTER DR , HIMMELE WALTER DR , MARTIN CHRISTOPH DR , POMMER ERNST-HEINRICH DR , SIEGEL HARDO DR
IPC: C07D295/02 , A01N43/00 , A01N43/40 , A01N43/84 , C07C45/69 , C07C45/74 , C07C47/225 , C07D211/14 , C07D265/30 , C07D295/033
Abstract: Cyclohexene derivatives of the formula I I where R1 and R2 are hydrogen or tert.-butyl and N and X are members of a heterocyclic ring in which X is an alkylene chain of four, five or six members, one of which may be a hetero-atom, such as oxygen, and where the alkylene radicals are unsubstituted or substituted by alkyl or by -CH2OH or its acetyl or propionyl derivative, and their salts are used in fungicides.
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14.
公开(公告)号:DE3160024D1
公开(公告)日:1983-02-24
申请号:DE3160024
申请日:1981-01-05
Applicant: BASF AG
Inventor: MARTIN CHRISTOPH DR , HIMMELE WALTER DR , SIEGEL HARDO DR
IPC: C12P7/40 , A01N43/84 , C07C27/00 , C07C33/18 , C07C33/20 , C07C33/24 , C07C41/00 , C07C43/20 , C07C43/23 , C07C43/303 , C07C51/00 , C07C57/30 , C07C59/64 , C07C67/00 , C07C69/612 , C07D265/30 , C07D295/02 , C07D295/03 , C12P7/16 , C12P7/22 , C12P7/24 , C12R1/865 , C07B19/00
Abstract: S-Configurated phenylpropane derivatives of the formula where R1 is alkyl, aryl or alkoxy, R2 is hydrogen, alkyl, aryl or alkoxy, and R3 is carboxyl or esterified carboxyl, acetalized formyl, hydroxymethyl or esterified hydroxymethyl, their preparation by microbiological hydrogenation, and their use for the preparation of fungicidal compounds.
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公开(公告)号:DK0464582T3
公开(公告)日:1996-05-28
申请号:DK91110432
申请日:1991-06-25
Applicant: BASF AG
Inventor: KIEFER HANS DR , MARTIN CHRISTOPH DR , GRIMMER JOHANNES
IPC: C07D475/14 , C12P17/18
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公开(公告)号:DE59107371D1
公开(公告)日:1996-03-21
申请号:DE59107371
申请日:1991-04-25
Applicant: BASF AG
Inventor: GRIMMER JOHANNES , KIEFER HANS DR , MARTIN CHRISTOPH DR
IPC: A61K9/16 , A61K31/525 , B01J2/04 , C07D475/14
Abstract: A process for the preparation of free-flowing, dust- and binder-free riboflavine spray granulates or microgranulates from finely divided pure riboflavine, characterised in that an aqueous or water-containing suspension of the pure finely divided riboflavine is subjected to a) fluidised bed spray drying, b) single component nozzle atomiser drying or c) disc atomiser drying, in particular fluidised bed spray drying, without binder being added to the suspension, and the riboflavine spray granulates or microgranulates obtainable according to this process.
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17.
公开(公告)号:DE4035485A1
公开(公告)日:1992-05-14
申请号:DE4035485
申请日:1990-11-08
Applicant: BASF AG
Inventor: GRIMMER JOHANNES , KIEFER HANS DR , MARTIN CHRISTOPH DR
IPC: C07D315/00 , C12P7/42 , C12P17/04
Abstract: Prodn. of gamma-lactones of formula (I) is effected by (a) heating a culture broth contg. the corresp. hydroxy acid to 60-130 deg. C without adding acid, and (b) extracting (I) in conventional mannner. In (I) R = 4C or 6C alkyl. The broth is heated at 80-120 deg. C for 30-150 (esp. 60-90) min. USE/ADVANTAGE - (I) are useful as flavours and fragrances. The process uses fewer chemicals than prior art processes employing mineral acids for lactonisation (cf.US4560656 and WO8912104), so the prods. should be more acceptable to consumers.
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公开(公告)号:DE4014262A1
公开(公告)日:1991-11-07
申请号:DE4014262
申请日:1990-05-04
Applicant: BASF AG
Inventor: GRIMMER JOHANNES , KIEFER HANS DR , MARTIN CHRISTOPH DR
IPC: A61K9/16 , A61K31/525 , B01J2/04 , C07D475/14
Abstract: A process for the preparation of free-flowing, dust- and binder-free riboflavine spray granulates or microgranulates from finely divided pure riboflavine, characterised in that an aqueous or water-containing suspension of the pure finely divided riboflavine is subjected to a) fluidised bed spray drying, b) single component nozzle atomiser drying or c) disc atomiser drying, in particular fluidised bed spray drying, without binder being added to the suspension, and the riboflavine spray granulates or microgranulates obtainable according to this process.
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公开(公告)号:DE4002066A1
公开(公告)日:1991-08-01
申请号:DE4002066
申请日:1990-01-25
Applicant: BASF AG
Inventor: FAUST TILLMANN DR , MEYER JOACHIM DR , WELLINGHOFF GEORG DR , GOESELE WALTER DR , MARTIN CHRISTOPH DR , GRIMMER JOHANNES
IPC: C07D475/14 , C12P17/18 , C12P25/00
Abstract: Riboflavin is removed from fermentation suspensions by them being heated at from 50 DEG to 90 DEG C. for from 1 to 3 hours, than cooled to from 0 DEG to 30 DEG C. over a period of from 1 to 5 hours, and subsequently being centrifuged to give a sediment fraction and liquid fraction in such a way that the sediment fraction contains predominantly riboflavin crystals as solid, and the liquid fraction contains virtually no crystalline riboflavin, and, where appropriate, resuspending the sediment fraction in from 0.5 to 2 parts by volume of water per part by volume of sediment fraction and repeating procedure c.
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公开(公告)号:DE3532134A1
公开(公告)日:1987-03-12
申请号:DE3532134
申请日:1985-09-10
Applicant: BASF AG
Inventor: BLOHM DIETMAR DR , MARTIN CHRISTOPH DR , HILLEN HEINZ DR , MARCINOWSKI STEFAN DR
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