公开(公告)号：EP2137126A1

公开(公告)日：2009-12-30

申请号：EP08771281.6

申请日：2008-06-17

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: C07C35/08 ,  C07C29/20 ,  B01J29/06

CPC classification number: C07C409/14 ,  B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  C07C29/50 ,  C07C45/33 ,  C07C45/53 ,  C07C407/00 ,  C07C2601/14 ,  C07C49/403 ,  C07C35/08

Abstract: Use of a high shear mechanical device incorporated into a process for the production of cyclohexanol is capable of decreasing mass transfer limitations, thereby enhancing the cyclohexanol production process. A system for the production of cyclohexanol from air oxidation of cyclohexane, the system comprising a high shear device, the outlet of the high shear device fluidly connected to the inlet of a reactor; the high shear device capable of providing a dispersion of air bubbles within a liquid comprising cyclohexane, the bubbles having an average bubble diameter of less than about 100 microns.

公开(公告)号：EP2114563A1

公开(公告)日：2009-11-11

申请号：EP08771783.1

申请日：2008-06-24

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: B01J23/85 ,  B01J21/04 ,  B01J23/76 ,  C10G45/04 ,  C10G11/00 ,  B01F7/26

CPC classification number: B01F7/00766 ,  B01F3/04099 ,  B01F5/104 ,  B01F5/106 ,  B01F13/1013 ,  B01F13/1016 ,  C10G45/02 ,  C10G49/007 ,  C10G2300/1025 ,  C10G2300/1033 ,  C10G2300/104 ,  C10G2300/1044 ,  C10G2300/1051 ,  C10G2300/1055 ,  C10G2300/207 ,  C10G2300/4081 ,  C10G2400/02 ,  C10G2400/04 ,  C10G2400/08

Abstract: A method for hydrodesulfurization by forming a dispersion comprising hydrogen-containing gas bubbles with a mean diameter of less than 1 micron dispersed in a liquid phase comprising sulfur-containing compounds. Desulfurizing a liquid stream comprising sulfur-containing compounds by subjecting a fluid mixture comprising hydrogen-containing gas and the liquid to a shear rate greater than 20,000 s−1 to produce a dispersion of hydrogen in a continuous phase of the liquid and introducing the dispersion into a fixed bed hydrodesulfurization reactor from which a reactor product is removed. Systems of apparatus for hydrodesulfurization are also presented.

公开(公告)号：EP2114553A2

公开(公告)日：2009-11-11

申请号：EP08771908.4

申请日：2008-06-25

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: B01F3/04 ,  B01F3/08 ,  B01F7/16

CPC classification number: C09K8/54 ,  B01F7/00766 ,  B01F13/1027 ,  B01F2215/0481 ,  E21B41/02 ,  Y10S516/923 ,  Y10S516/929

Abstract: A method for introducing inhibitor into a fluid to be treated by forming a dispersion comprising droplets, particles, or gas bubbles of the inhibitor dispersed in a continuous phase of a carrier, wherein the droplets, particles, or gas bubbles have a mean diameter of less than 5 microns, and wherein either the carrier is the fluid to be treated or the method further comprises introducing the dispersion into the fluid to be treated. A system for inhibiting an undesirable component, the system comprising at least one high shear mixing device comprising at least one generator comprising a rotor and a stator separated by a shear gap, wherein the high shear mixing device is capable of producing a tip speed of the rotor of greater than 22.9 m/s, and a pump for delivering a mixture of a carrier and an inhibitor to the high shear mixing device.

公开(公告)号：EP2563426B1

公开(公告)日：2018-01-03

申请号：EP11777787.0

申请日：2011-04-08

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  HASSAN, Aziz ,  ANTHONY, Rayford G.

IPC: A61M5/14 ,  A61M5/142 ,  A61M5/168 ,  A61J3/00 ,  A61K9/10 ,  A61K9/00 ,  B01F7/00 ,  B01F13/10

CPC classification number: A61J3/00 ,  A61K9/0019 ,  A61M5/142 ,  B01F7/00766 ,  B01F7/008 ,  B01F13/1016

Abstract: In this disclosure, a method is described wherein the method comprises mixing a therapeutic gas or a therapeutic liquid or a combination thereof and a liquid carrier in a high shear device to produce a dispersion; and administering the produced dispersion intravenously to a patient; wherein the produced dispersion contains nanobubbles of the therapeutic gas or droplets of the therapeutic liquid with a mean diameter of less than about 1.5 μm. In this disclosure, a system is also described wherein the system comprises a therapeutic gas source or a therapeutic liquid source or a combination thereof; a liquid carrier source; a high shear device (HSD) having an inlet, an outlet, at least one rotor, and at least one stator separated by a shear gap; and a pump configured to control the flow rate and residence time of a fluid passing through the high shear device.

公开(公告)号：EP2916948A1

公开(公告)日：2015-09-16

申请号：EP13853313.8

申请日：2013-11-04

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  HASSAN, Aziz ,  ANTHONY, Rayford G. ,  BORSINGER, Gregory G.

IPC: B01J23/882 ,  B01J23/75 ,  C01B31/18 ,  C01B31/20

CPC classification number: B01J23/8993 ,  B01J8/009 ,  B01J8/025 ,  B01J8/10 ,  B01J12/007 ,  B01J19/0073 ,  B01J19/2495 ,  B01J19/28 ,  B01J23/8892 ,  B01J23/8986 ,  B01J27/24 ,  B01J2208/0053 ,  B01J2208/00911 ,  B01J2219/00159 ,  C01B3/40 ,  C01B2203/0233 ,  C01B2203/062 ,  C01B2203/1241 ,  C07C29/153 ,  C10G2/33 ,  C10G50/00 ,  Y02P20/149 ,  Y02P20/52 ,  C07C31/04

Abstract: Herein disclosed is a catalyst composition for producing organic compounds comprising (a) a catalyst that promotes the oxidative coupling of methane (OCM) and a methane steam reforming (MSR) catalyst, wherein the catalyst composition causes oxidative dehydrogenation to form reactive species and oligomerization of the reactive species to produce the organic compounds; or (b) a catalyst that promotes syngas generation (SG) and a Fischer-Tropsch (FT) catalyst wherein the catalyst composition causes non-oxidative dehydrogenation to form reactive species and oligomerization of the reactive species to produce the organic compounds; or (c) a SG catalyst, a MSR catalyst, and a FT catalyst wherein the catalyst composition causes non-oxidative dehydrogenation to form reactive species and oligomerization of the reactive species to produce the organic compounds; or (d) a FT catalyst and a MSR catalyst wherein the catalyst composition causes reforming reactions and chain growing reactions to produce the organic compounds.

公开(公告)号：EP2834333A1

公开(公告)日：2015-02-11

申请号：EP13772671.7

申请日：2013-03-06

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  HASSAN, Aziz ,  ANTHONY, Rayford G.

IPC: C11B1/00 ,  C11B3/16

CPC classification number: B01F3/04 ,  A23D9/02 ,  B01F3/04531 ,  B01F7/00766 ,  B01F13/1016 ,  C11B1/00 ,  C11B1/02 ,  C11B1/10 ,  C11B3/00 ,  C11B3/14

Abstract: Herein disclosed is a method of processing oil, comprising providing a high shear device comprising at least one rotor and at least one complementarily-shaped stator configured to mix a gas with a liquid; contacting a gas with an oil in the high shear device, wherein the gas is an inert gas or a reactive gas; and forming a product, wherein the product is a solution, a dispersion, or combination thereof. Herein also disclosed is a high shear system for processing oil, comprising; at least one high shear device, having an inlet and at least one rotor and at least one complementarily-shaped stator configured to mix a gas with a liquid; a gas source fluidly connected to the inlet; an oil source fluidly connected to the inlet; and a pump positioned upstream of a high shear device, the pump in fluid connection with the inlet and the oil source.

公开(公告)号：EP2827982A2

公开(公告)日：2015-01-28

申请号：EP13764217.9

申请日：2013-03-19

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  HASSAN, Aziz ,  ANTHONY, Rayford G. ,  HASSAN, Alishah

IPC: B01J19/18 ,  B01F7/16

CPC classification number: C01B23/00 ,  B01F7/00766 ,  B01F13/1016 ,  B01J19/1806 ,  G21G5/00

Abstract: A system for converting a first substance into a second substance, the system including a mixing reactor configured to provide a reactant mixture comprising a first reactant, a second reactant, and a solvent; and a high shear device fluidly connected to the mixing reactor, wherein the high shear device comprises at least one rotor/stator set comprising a rotor and a complementarily-shaped stator symmetrically positioned about an axis of rotation and separated by a shear gap, wherein the shear gap is in the range of from about 10 microns to about 250 microns; and a motor configured for rotating the rotor about the axis of rotation, whereby energy can be transferred from the rotor to the reactants thereby inducing reactions between the first reactant and the second reactant to form a product.

公开(公告)号：EP2563426A2

公开(公告)日：2013-03-06

申请号：EP11777787.0

申请日：2011-04-08

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  HASSAN, Aziz ,  ANTHONY, Rayford G.

IPC: A61M5/14 ,  A61M5/142 ,  A61M5/168 ,  A61J3/00 ,  A61K9/10

CPC classification number: A61J3/00 ,  A61K9/0019 ,  A61M5/142 ,  B01F7/00766 ,  B01F7/008 ,  B01F13/1016

Abstract: In this disclosure, a method is described wherein the method comprises mixing a therapeutic gas or a therapeutic liquid or a combination thereof and a liquid carrier in a high shear device to produce a dispersion; and administering the produced dispersion intravenously to a patient; wherein the produced dispersion contains nanobubbles of the therapeutic gas or droplets of the therapeutic liquid with a mean diameter of less than about 1.5 μm. In this disclosure, a system is also described wherein the system comprises a therapeutic gas source or a therapeutic liquid source or a combination thereof; a liquid carrier source; a high shear device (HSD) having an inlet, an outlet, at least one rotor, and at least one stator separated by a shear gap; and a pump configured to control the flow rate and residence time of a fluid passing through the high shear device.

公开(公告)号：EP2563338A2

公开(公告)日：2013-03-06

申请号：EP11777788.8

申请日：2011-04-08

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  HASSAN, Aziz ,  ANTHONY, Rayford G.

IPC: A61K9/16 ,  A61K9/08 ,  A61K9/107 ,  A61J3/00 ,  A61M5/14

CPC classification number: A61J3/00 ,  A61K9/0019 ,  A61M5/142 ,  B01F7/00766 ,  B01F7/008 ,  B01F13/1016

Abstract: In this disclosure, methods and systems for drug delivery utilizing high shear are disclosed. In an embodiment, a method comprises (1) subjecting a therapeutic fluid containing a drug to high shear; and (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug in nano-size. In an embodiment, a method comprises (1) subjecting a drug carrier and a therapeutic fluid containing a drug to high shear; and (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug carrier loaded with the drug. In an embodiment, a method comprises (1) applying high shear to a drug carrier and a therapeutic fluid containing a drug; (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug-loaded carrier; and (3) modifying the drug-loaded carrier with a targeting moiety to obtain a modified drug-loaded carrier.

公开(公告)号：EP2401051A2

公开(公告)日：2012-01-04

申请号：EP10744351.7

申请日：2010-02-19

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  ANTHONY, Rayford G. ,  HASSAN, Aziz

IPC: B01D45/14 ,  B01D53/24 ,  B04B5/08

CPC classification number: B01D53/24 ,  B01D45/14 ,  B01D53/22 ,  B01D59/20 ,  B01D63/06 ,  B01D2256/24 ,  B01D2257/102 ,  B01D2257/504 ,  B01D2313/18 ,  B04B5/08 ,  B04B7/08 ,  Y02C10/10

Abstract: Herein disclosed is an apparatus comprising (1) a porous rotor symmetrically positioned about an axis of rotation and surrounding an interior space; (2) an outer casing, wherein the outer casing and the rotor are separated by an annular space; (3) a motor configured for rotating the rotor about the axis of rotation; (4) a feed inlet positioned along the axis of rotation and fluidly connected with the interior space; and (5) a first outlet, wherein the first outlet is fluidly connected with the interior space. Herein disclosed is a system, comprising at least one disclosed apparatus. Herein disclosed is also a method of separating a feed gas into a first fraction and a second fraction, wherein the first fraction has an average molecular weight lower than the average molecular weight of the second fraction.