公开(公告)号：CY1120466T1

公开(公告)日：2019-07-10

申请号：CY181100780

申请日：2018-07-26

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  LOUGHMAN JAMES ,  HOWARD ALAN ,  THURNHAM DAVID

IPC: A61P27/02 ,  A23K20/179 ,  A23K50/75 ,  A23L15/00 ,  A23L33/105 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A61K31/047 ,  A61K31/07 ,  A61K31/202 ,  A61K45/06

Abstract: Αποκαλύπτεταιμιασύνθεσηπουπεριλαμβάνειμεσοζεαξανθίνηγιαχρήσηωςσυμπλήρωμαδιατροφήςή πρόσθετοτροφίμωνγιακατανάλωσηαπότοστόμαγιαβελτίωσητηςοπτικήςικανότηταςενόςανθρώπου.

公开(公告)号：ES2675905T3

公开(公告)日：2018-07-13

申请号：ES12735605

申请日：2012-07-05

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  LOUGHMAN JAMES ,  HOWARD ALAN ,  THURNHAM DAVID

IPC: A61P27/02 ,  A23K20/179 ,  A23K50/75 ,  A23L15/00 ,  A23L33/105 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A61K31/047 ,  A61K31/07 ,  A61K31/202 ,  A61K45/06

Abstract: Un método de mejora del rendimiento visual de un sujeto humano sin degeneración macular relacionada con la edad que necesita dicha mejora, comprendiendo el método la etapa de administrar al sujeto una cantidad eficaz de una composición que comprende mesozeaxantina, luteína y zeaxantina como un complemento alimenticio o aditivo alimenticio, y en el que la realización del método mejora la discapacidad por deslumbramiento.

公开(公告)号：IE86532B1

公开(公告)日：2015-05-06

申请号：IE20130391

申请日：2013-12-23

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  HOWARD ALAN

IPC: A61B3/00 ,  A23L1/00 ,  A61K31/00

Abstract: A method of identifying a human subject, more likely than a subject selected at random from the general population, to have one or more of the following: (i) a low macular pigment concentration in the eye or eyes; (ii) a low visual performance, or (iii) an atypical "central dip" macular pigment distribution; the method comprising the steps of: measuring at least one cognitive function of the subject; comparing the measured cognitive function with a pre-determined threshold; and, if the measured cognitive function is below the threshold, declaring the subject as being more likely to have one or more of low macular pigment concentration in the eye or eyes, low visual performance or an atypical "central dip" macular pigment profile.

公开(公告)号：MX2014000067A

公开(公告)日：2014-07-28

申请号：MX2014000067

申请日：2012-07-05

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  LOUGHMAN JAMES ,  HOWARD ALAN ,  THURNHAM DAVID ,  BEATTY STEPHEN

IPC: A61P27/02 ,  A23L1/30 ,  A23L15/00 ,  A23L33/15 ,  A23L33/155 ,  A61K31/07

Abstract: Se describe una composición que comprende meso-zeaxantina para uso como un suplemento dietético o aditivo alimentario para consumo oral para mejorar el desmpeño visual de un sujeto humano.

公开(公告)号：IE86314B1

公开(公告)日：2013-12-04

申请号：IE20120309

申请日：2012-07-06

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  LOUGHMAN JAMES ,  HOWARD ALAN ,  THURNHAM DAVID

IPC: A23L1/00 ,  A61K31/00

Abstract: A composition comprising xanthophyll carotenoid mesozeaxanthin (MZ) for use as a dietary supplement or food additive for oral consumption for improving the visual performance of a human subject, in particular, a human subject not experiencing age-related macular degeneration (AMD). Visual performance may be assessed by measuring one or more of spatial contrast sensitivity function, (best corrected) visual acuity, glare disability, discomfort glare, ocular straylight, photostress recovery and S-cone sensitivity. The composition may also comprise lutein and/or zeaxanthin. A preferred combination is MZ/lutein/zeaxanthin in the ratio 10:10:2. Additional components may include one or more vitamins and/or minerals; a vegetable oil, fish oil and/or omega 3 fatty acid. The composition may be in the form of an egg obtained from a hen fed with a feed comprising MZ. A method of preparing the composition comprising the step of mixing an effective amount of MZ with an acceptable dietary diluent, excipient or carrier is also claimed.

公开(公告)号：HRP20181207T1

公开(公告)日：2018-12-14

申请号：HRP20181207

申请日：2018-07-25

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  LOUGHMAN JAMES ,  HOWARD ALAN ,  THURNHAM DAVID

IPC: A61P27/02 ,  A23K20/179 ,  A23K50/75 ,  A23L15/00 ,  A23L33/105 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A61K31/047 ,  A61K31/07 ,  A61K31/202 ,  A61K45/06

公开(公告)号：HUE038813T2

公开(公告)日：2018-11-28

申请号：HUE12735605

申请日：2012-07-05

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  LOUGHMAN JAMES ,  HOWARD ALAN ,  THURNHAM DAVID

IPC: A61P27/02 ,  A23K50/75 ,  A23L15/00 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A61K31/07 ,  A61K45/06

公开(公告)号：NZ618728A

公开(公告)日：2015-12-24

申请号：NZ61872812

申请日：2012-07-05

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  LOUGHMAN JAMES ,  HOWARD ALAN ,  THURNHAM DAVID

IPC: A61P27/02 ,  A23L15/00 ,  A23L33/15 ,  A23L33/155 ,  A61K31/07

Abstract: Disclosed is a use of meso-zeaxanthin (MZ), lutein, and zeaxanthin, in the manufacture of a composition for use in improving contrast sensitivity or glare disability in a human subject.

公开(公告)号：IE86584B1

公开(公告)日：2015-09-23

申请号：IE20130325

申请日：2012-07-06

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  LOUGHMAN JAMES ,  HOWARD ALAN ,  THURNHAM DAVID

IPC: A23L1/00 ,  A61K31/00

Abstract: Disclosed is a composition comprising MZ for use as a dietary supplement or food additive for oral consumption for improving the visual performance of a human subject with AMD.

公开(公告)号：IE20130325A1

公开(公告)日：2014-05-07

申请号：IE20130325

申请日：2012-07-06

Applicant: HOWARD FOUNDATION HOLDINGS LTD

Inventor： NOLAN JOHN ,  BEATTY STEPHEN ,  THURNHAM DAVID ,  LOUGHMAN JAMES ,  HOWARD ALAN

IPC: A23L1/00 ,  A61K31/00

Abstract: Disclosed is a composition comprising MZ for use as a dietary supplement or food additive for oral consumption for improving the visual performance of a human subject with ADM.