公开(公告)号：JPS6490156A

公开(公告)日：1989-04-06

申请号：JP24508587

申请日：1987-09-29

Applicant: KAO CORP

Inventor： MISU DAISUKE ,  OBAYASHI MICHIO ,  MANO TSUTOMU ,  KAWASE JIRO

IPC: A61K8/00 ,  A61K8/41 ,  A61Q5/10 ,  C07B61/00 ,  C07C67/00 ,  C07C213/00 ,  C07C213/02 ,  C07C215/16 ,  C09B53/02

Abstract: NEW MATERIAL:A compound of formula I (R is mono- or polyhydroxyalkyl) or its salts. EXAMPLE:1-N-(2'-Hydroxyethyl)amino-2-trifluoromethyl-4-aminobenzene. USE:A color-developing substance for dyeing corneal fibers. The substance is used in combination with a coupling agent which is used in usual oxidative dyeing to develop a wide range of colors from yellow through red to blue, further from gray to blackish brown, and its tone is high bright. The developed color is fast to light, washing and abrasion. PREPARATION:Catalytic hydrogenation of the compound of formula II is carried out in a solvent in the presence of a catalyst such as Pd or Pt at room temperature to the boiling point of the solvent under a hydrogen partial pressure of 1-250kg/cm to give the compound of formula I.

公开(公告)号：JPH02153973A

公开(公告)日：1990-06-13

申请号：JP30853388

申请日：1988-12-06

Applicant: KAO CORP

Inventor： KAWASE JIRO ,  TAGAMI HIDETOSHI ,  OBAYASHI MICHIO ,  MISU DAISUKE

IPC: A61K8/00 ,  A61K8/33 ,  A61K8/41 ,  A61Q5/10 ,  C09B67/42

Abstract: PURPOSE:To obtain the subject composition having high saturation of red color, intense color tone and good light-resistance, washing resistance and abrasion resistance by using aminophenols as a color-developing substance and an alpha- naphtol derivative, etc., as a coupling agent. CONSTITUTION:The objective composition contains aminophenols of formula I (X is halogen) (preferably 2-chloro-4-aminophenol) as a color-developing substance and an alpha-naphthol derivative of formula II (R is H or OH) (preferably 1-naphthol, 1,5-dihydroxynaphthol or 1,7-dihydroxynaphthol) and/or p-amino-o- cresol as a coupling agent. The molar ratio of the color-developing substance to the coupling agent is preferably 1:(0.8-1.5).

公开(公告)号：JPS6490116A

公开(公告)日：1989-04-06

申请号：JP24508487

申请日：1987-09-29

Applicant: KAO CORP

Inventor： MANO TSUTOMU ,  KAWASE JIRO ,  MISU DAISUKE ,  OBAYASHI MICHIO

IPC: A61K8/00 ,  A61Q5/10 ,  C09B53/02

Abstract: PURPOSE:To obtain a dyeing composition for keratose capable of dyeing in high chrome and in strong color tone, containing a p-phenylenediamine derivative as a developing substance and a coupling substance. CONSTITUTION:A dyeing composition comprising a novel p-phenylenediamine derivative shown by the formula (R is mono- or polyhydroxyalkyl) containing an introduced hydroxyalkyl group and a trifluoromethyl group or a salt thereof as a developing agent and a coupling substance (e.g. p-phenylenediamine). The blending ratio of the developing substance and the coupling substance is about 1:0.5-1:2 in molar ratio. Both the substances are blended with a wetting agent, emulsifying agent, solubilizer, thickening agent, stabilizer, touch improver, hair dressing base and perfume and the aimed substance is produced by a conventional procedure. The prepared substance is prepared into a form such as cream, emulsion, gel or solution.

公开(公告)号：JPH02188584A

公开(公告)日：1990-07-24

申请号：JP535689

申请日：1989-01-12

Applicant: KAO CORP

Inventor： KAWASE JIRO ,  MANO TSUTOMU ,  OBAYASHI MICHIO ,  MISU DAISUKE

IPC: C07D498/04 ,  C09B19/00 ,  C09B57/00

Abstract: NEW MATERIAL:A compound expressed by formula I [R1 and R2 represent H or methyl; X represents -N(R3)R4 (R3 and R4 represent H or methyl)]. USE:A pigment or dye, which exhibits a color tone of stable and high chroma. PREPARATION:A resorcinol derivative expressed by formula II (R5 and R6 represent H, halogen, 1-20C alkyl, alkoxy or hydroxy alkyl) (preferably resorcinol, 4-chlororesorcinol, etc.) is reacted with a pyrimidine derivative (preferably 2,4,5,6-tetraaminopyridine, etc.) expressed by formula III (R7 to R10 represent H, 1-20C alkyl, hydroxyalkyl, aralkyl, aminoalkyl, alkylaminoalkyl, aryl, thiol or formula IV), etc., to afford a compound expressed by formula V.

公开(公告)号：JPH0219576A

公开(公告)日：1990-01-23

申请号：JP16957188

申请日：1988-07-07

Applicant: KAO CORP

Inventor： KAWASE JIRO ,  MANO TSUTOMU ,  OBAYASHI MICHIO ,  MISU DAISUKE

IPC: C07D239/50 ,  D06P1/32

Abstract: PURPOSE:To obtain the subject composition, containing a specific developing substance and coupling substance and capable of dyeing keratinous fiber, such as hair, to a strong color tone with a high saturation. CONSTITUTION:A color developing substance consisting of a triaminopyrimidine derivative expressed by formula I or II or a salt (e.g. inorganic acid or organic acid salt) is combined with a coupling substance, e.g. a substance selected from resorcin, 2-methylresorcin and 4-chlororesorcin (forming orange to red color tone by this combination) or with 4-propyl-2,6-diaminopyridine or 3,4-dimethyl-2,6- diaminopyridine (forming bright yellow by this combination), etc., and converted into a creamy or emulsion form to dye keratinous fiber, such as hair, with excellent fastness to light and washing. Thereby, dyeing of a wide range of color tone from yellow to red to further gray to dark brown can be carried out by combination of the various developing substances with the coupling components.

公开(公告)号：JPH0242014A

公开(公告)日：1990-02-13

申请号：JP19292488

申请日：1988-08-02

Applicant: KAO CORP

Inventor： KAWASE JIRO ,  MANO TSUTOMU ,  MISU DAISUKE ,  OBAYASHI MICHIO

IPC: A61K8/00 ,  A61K8/41 ,  A61K8/42 ,  A61K8/46 ,  A61Q5/10

Abstract: PURPOSE:To obtain a horn-like fiber dyeing composition containing a diaminobenzene derivative or salt thereof as a developing substance, capable of dyeing horn-like fiber into intense color tone in high chroma and exhibiting excellent fastness. CONSTITUTION:In the aimed dyeing composition consisting of a developing substance and coupling substance, as the developing substance a diaminobenzene derivative expressed by the formula [R1 and R2 are H, 1-5C alkyl or hydroxyalkyl, -(CH2)nNR3R4, -(CH2)nCOOR5 (R3-R5 are H, 1-5C alkyl or hydroxyalkyl; n is 1-5); X is COOR6, CONHR7, SO3R8, etc., (R6-R8 is H, 1-5C alkyl or hydroxyalkyl) or salt thereof] is contained and a conventional wetting agent, emulsifier, solubilizer, etc., is added to above-mentioned main ingredients and the blend is prepared according to an ordinary method to provide the aimed product. The developing substance and coupling substance are used at a blend molar ratio of 1:0.5-1:2 and prepared in an agent type such as cream, emulsion, gel or solution.

公开(公告)号：JPS6422972A

公开(公告)日：1989-01-25

申请号：JP17844187

申请日：1987-07-17

Applicant: KAO CORP

Inventor： MANO TSUTOMU ,  KAWASE JIRO ,  MISU DAISUKE ,  OBAYASHI MICHIO

IPC: C09B67/42 ,  A61K8/00 ,  A61Q5/10 ,  D06P1/32 ,  D06P3/08

Abstract: PURPOSE:To provide the titled composition for dyeing hair, etc. in high chromaticity over a wide range from yellow, red, blue, gray to dark brown, comprising a trifluoromethylated aniline derivative as the developer and a coupling substance. CONSTITUTION:The objective composition comprising (A) as the developer, a trifluoromethylated aniline derivative of formula (R is amino or OH) or its salt (pref., 2-trifluoromethyl-1,4-diaminobenzene, 3-trifluoromethyl-4-aminophenol, or 2-trifluoromethyl-4-aminophenol) and (B) a coupling substance.

公开(公告)号：JPS63243083A

公开(公告)日：1988-10-07

申请号：JP7678287

申请日：1987-03-30

Applicant: KAO CORP

Inventor： MISU DAISUKE ,  OBAYASHI MICHIO ,  TAKAISHI NAOTAKE

IPC: C07D471/08 ,  C07B61/00

Abstract: PURPOSE:To obtain a cyclic amine useful as a urethanization catalyst, etc. in high purity and high yield, by heating bis(hydroxyethyl)piperazine in the presence of both a zirconium compound and an alkali metal acetate to carry out cyclization. CONSTITUTION:N,N'-Bis(2-hydroxyethyl)piperazine is heated in the presence of both a zirconium compound (example; zirconium dioxide or tetra-n- butoxyzirconium) or boron compound (example; diboron trioxide or tri-n-butoxy borane) and an alkali metal acetate (example; sodium acetate), preferably at 250-350 deg.C to carry out cyclization thereof and afford the aimed compound. The reaction is preferably carried out in the coexistence of tris[2-(2- methoxyethoxy)ethyl]amine.

公开(公告)号：JPS62246559A

公开(公告)日：1987-10-27

申请号：JP8395286

申请日：1986-04-11

Applicant: KAO CORP

Inventor： OBAYASHI MICHIO ,  TAKAISHI NAOTAKE

IPC: C07D295/02 ,  B01J27/135 ,  C07B61/00 ,  C07D487/08

Abstract: PURPOSE:To industrially and advantageously obtain the titled compound useful as an urethane catalyst, etc., in good yield in a short time, by cyclizing inexpensive N,N'-bis(2-hydroxyethyl)piperazine as a raw material in the presence of a specific catalyst while heating. CONSTITUTION:N,N'-Bis(2-hydroxyethyl)piperazine obtained by reacting piperazine with 2 equivalents ethylene oxide, etc., is cyclized in the presence of a titanium compound, e.g. tetra-n-butoxyethane, tetraisopropoxytitanium, TiO2, etc., as a catalyst and an alkali metal salt of acetic acid, e.g. sodium acetate, potassium acetate, etc., as a promoter, as necessary, in a solvent, e.g. polyethylene glycol, etc., preferably at 250-350 deg.C for 2-4hr under atmospheric pressure while heating to afford the aimed compound. EFFECT:The aimed compound is efficiently obtained by using the raw material readily available in a large amount at a low cost without using an expensive catalyst and special equipment.

公开(公告)号：JPS62240674A

公开(公告)日：1987-10-21

申请号：JP8395386

申请日：1986-04-11

Applicant: KAO CORP

Inventor： OBAYASHI MICHIO ,  TAKAISHI NAOTAKE

IPC: C07D295/02

Abstract: PURPOSE:Crude 1,4-diazabicyclo[2,2,2]octane containing ethylene glycol is treated with an inexpensive isocyanate and distilled to effect purification whereby the titled compound of high purity is readily obtained. CONSTITUTION:A crude 1,4-diazabicyclo[2,2,2]octane containing at least ethylene glycol which is obtained by cyclization of N,N-bis(2-hydroxyethyl)piperazine is treated with an isocyanate to polymerize impurities and distilled to effect purification. Thus, the objective compound of high purity of 96-98% is obtained. Tolylene diisocyanate or hexamethylene diisocyanate is preferably used as the isocyanate. EFFECT:The purification can be done without use of a large amount of solvents with simple installation and operations. USE:Urethane catalyst and others.