公开(公告)号：EP4137811A1

公开(公告)日：2023-02-22

申请号：EP22177489.6

申请日：2016-08-25

Applicant: Life Technologies Corporation

Inventor： BUSTILLO, James ,  GRAY, Jeremy ,  OWENS, Jordan

IPC: G01N27/414

Abstract: An apparatus includes a substrate; a gate structure disposed over the substrate and having an upper surface; a well structure disposed over the substrate and defining a well over the upper surface of the gate structure; a conductive layer disposed on the upper surface of the gate structure and at least partially extending along a wall of the well in the well structure; and a dielectric structure disposed over the well structure and defining an opening to the well.

公开(公告)号：EP3249057B1

公开(公告)日：2019-05-01

申请号：EP17181624.2

申请日：2014-03-13

Applicant: Life Technologies Corporation

Inventor： LIGHT, David ,  HINZ, Wofgang ,  CICERO, Ronald ,  INMAN, Christina ,  KENNEY, Paul ,  MASTROIANNI, Alexander ,  ROZHKOV, Roman ,  WANG, Yufang ,  GRAY, Jeremy ,  GLAZER, Marc ,  GREMYACHINSKIY, Dmitriy

IPC: C12Q1/68

公开(公告)号：EP3265585B1

公开(公告)日：2018-12-26

申请号：EP16711079.0

申请日：2016-03-04

Applicant: Life Technologies Corporation

Inventor： WAGGONER, Phil ,  BALL, James ,  HINZ, Wolfgang ,  MINTO, Michael ,  PARKER, Scott ,  COX, David ,  MASTROIANNI, Alexander ,  GRAY, Jeremy ,  GLAZER, Marc ,  GORRELL, Kimberly

IPC: C12Q1/6869 ,  G01N27/414

CPC classification number: C12Q1/6869 ,  G01N27/4145 ,  C12Q2527/119 ,  C12Q2527/125 ,  C12Q2565/607

Abstract: A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

公开(公告)号：EP2971089B1

公开(公告)日：2017-07-19

申请号：EP14716714.2

申请日：2014-03-13

Applicant: Life Technologies Corporation

Inventor： LIGHT, David ,  HINZ, Wolfgang ,  CICERO, Ronald ,  INMAN, Christina ,  KENNEY, Paul ,  MASTROIANNI, Alexander ,  ROZHKOV, Roman ,  WANG, Yufang ,  GRAY, Jeremy ,  GLAZER, Marc ,  GREMYACHINSKIY, Dmitriy

IPC: C12Q1/68

CPC classification number: C12Q1/6837 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q2523/101

公开(公告)号：EP3766991A1

公开(公告)日：2021-01-20

申请号：EP20195062.3

申请日：2016-03-04

Applicant: Life Technologies Corporation

Inventor： WAGGONER, Phil ,  BALL, James ,  HINZ, Wolfgang ,  MINTO, Michael ,  PARKER, Scott ,  COX, David ,  MASTROIANNI, Alexander ,  GRAY, Jeremy ,  GLAZER, Marc ,  GORRELL, Kimberly

IPC: C12Q1/6869 ,  G01N27/414

Abstract: A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

公开(公告)号：EP3707274A1

公开(公告)日：2020-09-16

申请号：EP18808182.2

申请日：2018-11-07

Applicant: Life Technologies Corporation

Inventor： ROSENBAUM, Abraham ,  SEEGER, Collyn ,  GRAY, Jeremy ,  YU, Hua

IPC: C12Q1/6806 ,  C12Q1/6874

公开(公告)号：EP3249057A1

公开(公告)日：2017-11-29

申请号：EP17181624.2

申请日：2014-03-13

Applicant: Life Technologies Corporation

Inventor： LIGHT, David ,  HINZ, Wofgang ,  CICERO, Ronald ,  INMAN, Christina ,  KENNEY, Paul ,  MASTROIANNI, Alexander ,  ROZHKOV, Roman ,  WANG, Yufang ,  GRAY, Jeremy ,  GLAZER, Marc ,  GREMYACHINSKIY, Dmitriy

IPC: C12Q1/68

CPC classification number: C12Q1/6837 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q1/6869 ,  C12Q2523/101 ,  C12Q2527/119 ,  C12Q2535/122 ,  C12Q2547/107 ,  C12Q2563/159 ,  C12Q2565/537 ,  C12Q2523/301 ,  C12Q2523/32

Abstract: A method of forming a polymer matrix array includes applying an aqueous solution into wells of a well array. The aqueous solution includes polymer precursors. The method further includes applying an immiscible fluid over the well array to isolate the aqueous solution within the wells of the well array and polymerizing the polymer precursors isolated in the wells of the well array to form the polymer matrix array. An apparatus includes a sensor array, a well array corresponding to the sensor array, and an array of polymer matrices disposed in the well array.

Abstract translation: 形成聚合物基质阵列的方法包括将水溶液施加到孔阵列的孔中。 水溶液包含聚合物前体。 该方法进一步包括在井阵列上施加不混溶流体以隔离井阵列的井内的水溶液，并聚合在井阵列的井中分离的聚合物前体以形成聚合物基质阵列。 一种装置包括传感器阵列，对应于传感器阵列的井阵列以及布置在井阵列中的聚合物矩阵的阵列。

公开(公告)号：EP3164701A1

公开(公告)日：2017-05-10

申请号：EP15738556.8

申请日：2015-07-01

Applicant: Life Technologies Corporation

Inventor： CICERO, Ronald L. ,  GLAZER, Marc ,  WANG, Yufang ,  INMAN, Christina E. ,  GRAY, Jeremy ,  KOSCINSKI, Joseph ,  BALL, James ,  WAGGONER, Phil ,  MASTROIANNI, Alexander

IPC: G01N27/414 ,  C12Q1/68 ,  G01N33/543

CPC classification number: G01N27/414 ,  G01N27/4145

Abstract: A sensor component includes a sensor including a sensor surface and a reaction site in cooperation with the sensor and exposing the sensor surface. The reaction site including a reaction site surface. A surface agent is bound to the reaction site surface or the sensor surface. The surface agent includes a surface active functional group reactive with Bronsted base or Lewis acid functionality on the reaction site surface or the sensor surface and including distal functionality that does not have a donor electron pair.

Abstract translation: 传感器组件包括传感器，传感器包括传感器表面和与传感器协作并暴露传感器表面的反应部位。 反应部位包括反应部位表面。 表面剂与反应部位表面或传感器表面结合。 表面活性剂包括表面活性官能团，其在反应位点表面或传感器表面上与布朗斯台德碱或路易斯酸官能团反应并且包括不具有施主电子对的远端官能团。

公开(公告)号：EP4095264A1

公开(公告)日：2022-11-30

申请号：EP22185816.0

申请日：2016-03-04

Applicant: Life Technologies Corporation

Inventor： WAGGONER, Phil ,  BALL, James ,  HINZ, Wolfgang ,  MINTO, Michael ,  PARKER, Scott ,  COX, David ,  MASTROIANNI, Alexander ,  GRAY, Jeremy ,  GLAZER, Marc ,  GORRELL, Kimberly

IPC: C12Q1/6869 ,  G01N27/414

Abstract: A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

公开(公告)号：EP3341718A1

公开(公告)日：2018-07-04

申请号：EP16759949.7

申请日：2016-08-25

Applicant: Life Technologies Corporation

Inventor： BUSTILLO, James ,  GRAY, Jeremy ,  OWENS, Jordan

IPC: G01N27/414

CPC classification number: G01N27/4148 ,  G01N27/4145 ,  H01L29/42324

Abstract: An apparatus includes a substrate; a gate structure disposed over the substrate and having an upper surface; a well structure disposed over the substrate and defining a well over the upper surface of the gate structure; a conductive layer disposed on the upper surface of the gate structure and at least partially extending along a wall of the well in the well structure; and a dielectric structure disposed over the well structure and defining an opening to the well.