公开(公告)号：EP2464754A2

公开(公告)日：2012-06-20

申请号：EP10808855.0

申请日：2010-08-13

Applicant: Life Technologies Corporation

Inventor： MULERO, Julio ,  GREEN, Robert ,  LAGACE, Robert ,  HENNESSY, Lori

IPC: C12Q1/68 ,  C12P19/34 ,  G01N33/48

CPC classification number: C07H21/04 ,  C12Q1/6879 ,  C12Q2600/156

Abstract: Disclosed are methods for gender determination in the intron 1 region of the amelogenin locus and a newly discovered single nucleotide polymorphism (SNP) within the X chromosome of the amelogenin locus which can cause allelic dropout. Also disclosed are kits useful in gender determination.

公开(公告)号：EP2619322A1

公开(公告)日：2013-07-31

申请号：EP11767107.3

申请日：2011-09-21

Applicant: Life Technologies Corporation

Inventor： GREEN, Robert ,  WANG, Dennis ,  MULERO, Julio ,  LAGACE, Robert

IPC: C12Q1/68

CPC classification number: C12Q1/6827 ,  C12Q1/686 ,  C12Q1/6888 ,  C12Q2537/143 ,  C12Q2600/156

Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.

公开(公告)号：EP2893035A1

公开(公告)日：2015-07-15

申请号：EP13713024.1

申请日：2013-03-14

Applicant: Life Technologies Corporation

Inventor： BORMANN CHUNG, Christina ,  MULERO, Julio ,  HENNESSY, Lori

IPC: C12Q1/68

CPC classification number: C12Q1/6858 ,  C12Q1/686 ,  C12Q1/6879 ,  C12Q1/6888 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2525/101 ,  C12Q2525/204 ,  C12Q2537/143

Abstract: Novel Y-STR multiplex analysis designs, primer design, allelic ladders, methods of use and kits are disclosed, including the use of primer sets designed to provide amplicons for at least 11 Y-STR loci having a base pair size of less than about 220 bp, as well as the use of primer sets designed to provide amplicons for at least 22 Y-STR loci including at least 5 rapidly mutating loci.

Abstract translation: 公开了新颖的Y-STR多重分析设计，引物设计，等位基因梯，使用方法和试剂盒，包括使用引物组设计用于为至少11个碱基对大小小于约220的Y-STR基因座提供扩增子 bp，以及设计用于为至少22个Y-STR基因座提供扩增子的引物组的使用，包括至少5个快速变异基因座。

公开(公告)号：EP2619322B1

公开(公告)日：2015-06-03

申请号：EP11767107.3

申请日：2011-09-21

Applicant: Life Technologies Corporation

Inventor： GREEN, Robert ,  WANG, Dennis ,  MULERO, Julio ,  LAGACE, Robert

IPC: C12Q1/68

CPC classification number: C12Q1/6827 ,  C12Q1/686 ,  C12Q1/6888 ,  C12Q2537/143 ,  C12Q2600/156

Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.

公开(公告)号：EP2504433B1

公开(公告)日：2014-10-29

申请号：EP10833985.4

申请日：2010-11-24

Applicant: Life Technologies Corporation

Inventor： GREEN, Robert ,  MULERO, Julio ,  HENNESSY, Lori ,  LAGACE, Robert ,  CHANG, Chien-Wei

IPC: C12N15/11 ,  C12Q1/68

CPC classification number: C12Q1/6876 ,  C12Q2600/156 ,  C12Q2600/166

公开(公告)号：EP2464754B1

公开(公告)日：2014-03-12

申请号：EP10808855.0

申请日：2010-08-13

Applicant: Life Technologies Corporation

Inventor： MULERO, Julio ,  GREEN, Robert ,  LAGACE, Robert ,  HENNESSY, Lori

IPC: C12Q1/68 ,  C12P19/34 ,  G01N33/48

CPC classification number: C07H21/04 ,  C12Q1/6879 ,  C12Q2600/156

公开(公告)号：EP2488668A2

公开(公告)日：2012-08-22

申请号：EP10824211.6

申请日：2010-10-15

Applicant: Life Technologies Corporation

Inventor： MULERO, Julio ,  MALICDEM, Michael ,  LAGACE, Robert

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  C12Q1/6858 ,  C12Q1/6888 ,  C12Q2525/117 ,  C12Q2563/107 ,  C12Q2600/156