公开(公告)号：JP2010038702A

公开(公告)日：2010-02-18

申请号：JP2008201356

申请日：2008-08-05

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： MIYOSHI KOJI ,  YAMADA RYOSUKE ,  AGAWA MASAHIRO ,  MURAKAMI KENJI ,  TANIDA TAKAHIKO ,  KUROKAWA HIDEYUKI

IPC: G01N21/78

Abstract: PROBLEM TO BE SOLVED: To provide a measuring apparatus for calibrating the optical noise caused by the surface roughness (irregularities) of a biosensor.
SOLUTION: The measuring apparatus 110 is a measuring apparatus for (a) performing chromatography measurement with respect to the sample spotted on the biosensor 120 and equipped with a photographing unit (a light emitting device 111, an iris 112, a condensing lens 113, a photodetector 114 and a signal converting part 115) for (b) photographing the measuring part (a developing part 122 and a reaction part 123) of the biosensor 120 to form the image signal of the measuring part, a control part 119 for (c) controlling the photographing unit to allow the photographing unit to photograph the measuring part before and after the sample is developed on the measuring part and an image processing part 116 for (d) using the image signal formed by the photographing unit before the sample is developed on the measuring part to remove the noise component inherent to each biosensor contained in the image signal formed by the photographing unit after the sample is developed on the measuring part.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于校准由生物传感器的表面粗糙度（不规则性）引起的光学噪声的测量装置。 解决方案：测量装置110是用于（a）相对于点样在生物传感器120上的样品进行色谱测量的测量装置，其配备有拍摄单元（发光装置111，虹膜112，聚光透镜 113，光电检测器114和信号转换部分115），用于（b）拍摄生物传感器120的测量部分（显影部分122和反应部分123）以形成测量部分的图像信号;控制部分119，用于 （c）控制拍摄单元以允许拍摄单元在测量部件上显影样品之前和之后拍摄测量部件，以及图像处理部件116，用于（d）在样品之前使用由拍摄单元形成的图像信号 被开发在测量部分上以去除在测量部分上显影样品之后由拍摄单元形成的图像信号中包含的每个生物传感器固有的噪声分量。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2009156716A

公开(公告)日：2009-07-16

申请号：JP2007335425

申请日：2007-12-27

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： TANIDA TAKAHIKO ,  MIYOSHI KOJI ,  AGAWA MASAHIRO ,  KUROKAWA HIDEYUKI ,  YAMADA RYOSUKE ,  MATSUDA YOKO ,  TAKAHASHI MITSUE

IPC: G01N33/543 ,  G01N21/17

CPC classification number: G01N21/8483

Abstract: PROBLEM TO BE SOLVED: To provide a solution measurement method and a solution measurement apparatus for favorably detecting a flow of a to-be-inspected solution as a specimen, and accurately calculating the quantity of a to-be-measured material in a state that the development quantity of the to-be-inspected solution is uniform.
SOLUTION: In the solution measurement method, the specimen X is temporarily accumulated in a capillary 8 as a solution reservoir of a test piece when the specimen X as the to-be-inspected solution is added to the test piece. The specimen X is developed from the capillary 8 to a development layer of the test piece. An optical characteristic is measured in a predetermined to-be-measured section. The quantity of the to-be-measured material contained in the specimen X is calculated. The to-be-measured section is measured when the specimen X in the capillary 8 decreases to the predetermined quantity or less. The quantity of the to-be-measured material contained in the specimen X is calculated based on the measurement value. The method can detect an event that the certain quantity of the specimen X flows from the capillary 8 to the to-be-measured section of the development layer, and can accurately calculate the quantity of the to-be-measured material in a state that the development quantity of the specimen X is uniform.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种溶液测量方法和溶液测量装置，用于有利地检测作为样品的待检测溶液的流动，并且精确地计算待测物质的量 待检查方案的开发量均匀的状态。 解决方案：在溶液测量方法中，当将作为待检查溶液的样品X添加到试验片中时，试样X临时堆积在作为试验片的溶液储存器的毛细管8中。 样品X从毛细管8显影到试片的显影层。 在预定的待测部分中测量光学特性。 计算样本X中包含的被测量材料的量。 当毛细管8中的样本X减少到预定量或更小时，测量被测量部分。 根据测定值计算试样X中含有的被测量材料的量。 该方法可以检测一定量的样品X从显影层的毛细管8流向待测部位的事件，并且能够精确地计算待测材料的量， 样本X的显影量是均匀的。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2010107401A

公开(公告)日：2010-05-13

申请号：JP2008280621

申请日：2008-10-31

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： TANIDA TAKAHIKO ,  AGAWA MASAHIRO ,  MURAKAMI KENJI ,  KUROKAWA HIDEYUKI ,  YAMADA RYOSUKE ,  MIYOSHI KOJI

IPC: G01N33/52 ,  G01N31/22

Abstract: PROBLEM TO BE SOLVED: To easily give identification information to a chromatography testpiece.
SOLUTION: In the manufacturing process of the chromatography testpiece 1, identification information is easily given to the chromatography testpiece 1 by giving identification information by a code to the chromatography testpiece 1.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：为了容易地向色谱试片提供识别信息。 解决方案：在色谱试片1的制造过程中，通过向色谱试片1的编码提供识别信息，容易地向色谱试片1提供识别信息。版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2010101715A

公开(公告)日：2010-05-06

申请号：JP2008272567

申请日：2008-10-23

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： YAMADA RYOSUKE ,  AGAWA MASAHIRO ,  MIYOSHI KOJI ,  MURAKAMI KENJI ,  KUROKAWA HIDEYUKI ,  TANIDA TAKAHIKO

IPC: G01N21/27 ,  G01N21/78 ,  G01N31/22

Abstract: PROBLEM TO BE SOLVED: To provide an analysis method for obtaining the concentration data of a specimen, by receiving the light from the specimen by an image sensor through an optical system, such as an optical filter, and to reduce measurement errors caused due to the shift in the coloration position of an analyzer.
SOLUTION: The analysis method includes a first step of calculating the luminance value [function F (r)] of the light from the specimen on a testpiece, beforehand; a second step of detecting the shift quantity R from the measuring region on the testpiece becoming a standard with respect to the measuring region on the testpiece which is an analysis target and calculating the luminance value [function F (r-R)] of the specimen on the testpiece; a third step of setting the correction factor [function G (r)] of the luminance, corresponding to the shift quantity using the prior luminance value and the shift quantity; a fourth step of correcting the luminance value calculated in the second step or the value, corresponding to the luminance value using the set correction factor; and a fifth step of obtaining the concentration data of the specimen, on the basis of the correction value after correction.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：为了提供一种用于获得样本的浓度数据的分析方法，通过诸如滤光器的光学系统通过图像传感器接收来自样本的光，并且减少由于 由于分析仪的着色位置的变化。 解决方案：分析方法包括：预先计算来自试样上的试样的光的亮度值[函数F（r）]的第一步骤; 从作为分析对象的试件上的测量区域成为标准的试验片上的测量区域的移动量R的检测的第二步骤，计算试样的亮度值[函数F（rR）] 试件; 第三步骤，使用先前的亮度值和偏移量来设置对应于移位量的亮度的校正因子[函数G（r）]; 第四步骤，使用所设定的校正因子来校正在第二步骤中计算的亮度值或对应于亮度值的值; 以及第五步骤，根据校正后的校正值，求出样本的浓度数据。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2010019610A

公开(公告)日：2010-01-28

申请号：JP2008178535

申请日：2008-07-09

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： TANIDA TAKAHIKO ,  AGAWA MASAHIRO ,  MURAKAMI KENJI ,  KUROKAWA HIDEYUKI ,  YAMADA RYOSUKE

IPC: G01N33/543 ,  G01N21/27 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To determine automatically a measurement start time, and to measure at the optimum timing.
SOLUTION: A specimen is spot-contacted with a chromatography test piece 2 mounted on an immunochromatography measuring device 1, and a spot-contact detection operation is started simultaneously with mounting by using an LED 10 and a photodiode 11 provided outside the device, to thereby detected the spot-contacted specimen. Consequently, the start time of immunochromatography measurement can be determined automatically by detecting spot contact just after spot contact, and immunochromatography measurement can be performed at the optimum timing.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：自动确定测量开始时间，并在最佳定时进行测量。 解决方案：将样品与安装在免疫色谱测量装置1上的色谱试片2点接触，并通过使用设置在装置外部的LED 10和光电二极管11与安装同时开始点接触检测操作 ，从而检测到点接触的样品。 因此，可以通过在点接触之后检测点接触来自动确定免疫色谱测量的开始时间，并且可以在最佳定时进行免疫色谱测量。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2009150856A

公开(公告)日：2009-07-09

申请号：JP2007331274

申请日：2007-12-25

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： AGAWA MASAHIRO ,  KUROKAWA HIDEYUKI ,  TANIDA TAKAHIKO ,  YAMADA RYOSUKE ,  MATSUDA YOKO

IPC: G01N33/543 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To provide a method and an apparatus for sample analysis, capable of satisfactorily acquiring individual information as minimizing increases in facility costs and the large formation of the apparatus even when using a test piece 1 having a surface in which concentration information appears and the opposite surface provided with the individual information such as code information 22, and to provide the test piece.
SOLUTION: Code information 22, the individual information on the individual test piece 1, is indicated on the surface opposite to a concentration measuring surface of the test piece 1 in which concentration information of an analyte appears in the test piece 1. A photo-detection means arranged in front of the concentration measuring surface of the test piece 1 acquires concentration information of the analyte at the concentration measuring surface in the test piece 1 and acquires the code information 22 of the surface opposite to the concentration measuring surface through the test piece 1.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：为了提供一种用于样品分析的方法和装置，即使使用具有表面的试件1，也能够令人满意地获取个体信息，使得设备成本的增加最小化，以及装置的大型形成 出现浓度信息，并且提供具有诸如代码信息22的个人信息的相对表面，并提供测试片。

解决方案：代码信息22，在与测试件1的浓度信息相对的表面相对的表面上指示个别测试件1上的个人信息。 布置在测试件1的浓度测量表面前面的光检测装置获取测试片1中的浓度测量表面上的分析物的浓度信息，并通过该测量表面获取与浓度测量表面相对的表面的代码信息22 试卷1.版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009115470A

公开(公告)日：2009-05-28

申请号：JP2007285616

申请日：2007-11-02

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： AGAWA MASAHIRO ,  MIYOSHI KOJI ,  TAKAHASHI MITSUE ,  KUROKAWA HIDEYUKI ,  TANIDA TAKAHIKO ,  YAMADA RYOSUKE ,  MATSUDA YOKO

IPC: G01N33/543 ,  G01N21/78

CPC classification number: G01N21/8483 ,  G01N30/95 ,  G01N33/54386 ,  G01N33/558 ,  G01N2201/1242

Abstract: PROBLEM TO BE SOLVED: To provide a chromatographic inspection apparatus capable of detecting the deterioration of a test piece at chromatographic inspection, and performing accurate inspection.
SOLUTION: With a liquid sample developed in a chromatographic test piece 1, the difference of luminance between two prescribed points or the amount of a luminance change in a prescribed region is measured and compared with a predetermined specified value. Since it is possible to automatically detect deterioration such as deterioration in hydrophilicity at a lower part of a liquid-impermeable sheet material 8 during chromatography inspection, accurate inspection can be performed.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种能够在色谱检查中检测试片的劣化并进行精确检查的色谱检查装置。 解决方案：使用在色谱试片1中显影的液体样品，测量两个规定点之间的亮度差或规定区域中的亮度变化量，并将其与预定的规定值进行比较。 由于能够自动检测色谱检查时的不透液性片材8的下部的亲水性劣化的劣化，因此可以进行精确的检查。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009085695A

公开(公告)日：2009-04-23

申请号：JP2007254036

申请日：2007-09-28

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： MIYOSHI KOJI ,  AGAWA MASAHIRO ,  TANIDA TAKAHIKO ,  YAMADA RYOSUKE ,  KUROKAWA HIDEYUKI ,  MATSUDA YOKO

IPC: G01N33/543 ,  G01N21/27 ,  G01N21/78

CPC classification number: G01N21/78 ,  G01N21/8483

Abstract: PROBLEM TO BE SOLVED: To provide a biosensor enhanced in reliability and measuring precision, and a measuring method using it.
SOLUTION: In the biosensor for optically detecting a signal to measure the concentration of an analyzing target, a liquid sample is developed on a developing part 13 when the liquid sample is supplied to a supply part 12, a reaction part 14 is colored corresponding to the concentration of the analyzing target and the absorbance of the reaction part 14 is read but, at this time, the developing speed of the liquid sample is read to measure the amount of the liquid sample supplied to the supply part 12.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供可靠性和测量精度提高的生物传感器以及使用它的测量方法。 解决方案：在用于光学检测分析对象的浓度的信号的生物传感器中，当液体样品被供应到供应部分12时，液体样品在显影部分13上显影，反应部分14着色 对应于分析对象物的浓度和反应部分14的吸光度被读取，此时，读取液体样本的显影速度，以测量供给到供给部分12的液体试样的量。

版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009085694A

公开(公告)日：2009-04-23

申请号：JP2007254035

申请日：2007-09-28

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： YAMADA RYOSUKE ,  AGAWA MASAHIRO ,  KUROKAWA HIDEYUKI ,  TANIDA TAKAHIKO ,  MATSUDA YOKO

IPC: G01N21/17 ,  G01N21/27

Abstract: PROBLEM TO BE SOLVED: To provide an analyzer capable of detecting focus blur quantity from the image data of the fiber structure of the surface of a photographed test piece to determine the measuring region corresponding to the focus blur quantity.
SOLUTION: The analyzer comprises the test piece 1 having a fiber structure, an imaging element 7 for acquiring the image data of the test piece 1, a light emitting element 4 for irradiating the test piece 7 with light and an optical element 11 for forming the image data of the test piece 1 on the surface of the imaging element 7 and the relation between the unevenness data of the surface of the test piece 1 obtained from the photographed image data and the focus blur quantity of an optical system is calculated to determine the measuring region corresponding to the focus blur quantity.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种能够从拍摄的测试片的表面的光纤结构的图像数据中检测焦点模糊量的分析器，以确定与聚焦模糊量相对应的测量区域。 解决方案：分析仪包括具有纤维结构的测试片1，用于获取测试片1的图像数据的成像元件7，用于用光照射测试片7的光发射元件4和光学元件11 用于在成像元件7的表面上形成测试片1的图像数据，并且计算从拍摄的图像数据获得的测试片1的表面的不平坦数据与光学系统的聚焦模糊量之间的关系 以确定与聚焦模糊量相对应的测量区域。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009052931A

公开(公告)日：2009-03-12

申请号：JP2007217957

申请日：2007-08-24

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： TANIDA TAKAHIKO ,  KUROKAWA HIDEYUKI ,  MATSUDA YOKO

IPC: G01N15/08

Abstract: PROBLEM TO BE SOLVED: To provide an accurate and quick liquid spreading speed measuring device of a porous substrate, by automatizing setting of the porous substrate on the liquid spreading speed measuring device, and by imaging a penetration state of liquid used for measurement into the porous substrate.
SOLUTION: Two liquid reservoirs are provided, namely, a liquid reservoir A3 for storing measuring liquid on a base plate 2, and a liquid reservoir B4 over the liquid reservoir A3. A plurality of porous substrates 5 are laminated and fixed on a plate 6. Then, the plate 6 is lowered to allow the liquid reservoirs A3, B4 to reach the end of the porous substrates 5, and a penetration state of the measuring liquid into the porous substrates from each liquid reservoir is imaged. Liquid spreading speed is measured by processing the imaged image.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：为了提供一种多孔基材的准确且快速的液体扩散速度测量装置，通过使液体扩散速度测量装置上的多孔基材的设定自动化，并且通过成像用于测量的液体的穿透状态 进入多孔基材。 解决方案：提供两个液体储存器，即用于在基板2上存储测量液体的液体储存器A3和液体储存器A3上的液体储存器B4。 将多个多孔基材5层压并固定在板6上。然后，降低板6以使液体储存器A3，B4到达多孔基板5的端部，并将测量液体的穿透状态插入到 对来自每个液体储存器的多孔基底进行成像。 通过处理成像图像来测量液体扩散速度。 版权所有（C）2009，JPO＆INPIT