公开(公告)号：WO2008120155A2

公开(公告)日：2008-10-09

申请号：PCT/IB2008051166

申请日：2008-03-28

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  BYSTROV DANIEL ,  YOUNG STEWART ,  PEKAR VLADIMIR ,  COCOSCO CHRISTIAN A

Inventor： BYSTROV DANIEL ,  YOUNG STEWART ,  PEKAR VLADIMIR ,  COCOSCO CHRISTIAN A

IPC: G06T17/40 ,  G06F19/00

CPC classification number: G06T19/00 ,  G06F19/321 ,  G06T2210/41

Abstract: The invention relates to a data processing apparatus and a method for providing visualisation parameters controlling the display of a medical image (12). The data processing apparatus comprises a mapping component (16). The mapping component (16) is arranged to receive a current dataset (15) corresponding to the medical image and comprising a content description thereof,to compare the content description of the current dataset (15) witha content description ofa pluralityofstored datasets, to select at least one further dataset out of the plurality of stored datasets, to retrieve stored visualisation parameters corresponding to the at least one further dataset, and to prepare the retrieved visualisation parameters as the visualisation parameters controlling the display of the medical image (12).

Abstract translation: 本发明涉及一种用于提供控制医学图像（12）的显示的可视化参数的数据处理装置和方法。 数据处理装置包括映射组件（16）。 映射组件（16）被布置为接收与医学图像相对应的当前数据集（15），并且包括其内容描述，以将当前数据集（15）的内容描述与多个保存数据集的内容描述进行比较，以在 在多个存储的数据集中的至少一个另外的数据集，以检索与至少一个另外的数据集相对应的存储的可视化参数，并且准备所检索的可视化参数作为控制医学图像（12）的显示的可视化参数。

公开(公告)号：WO2005057495B1

公开(公告)日：2005-08-11

申请号：PCT/IB2004052711

申请日：2004-12-08

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  PEKAR VLADIMIR ,  BYSTROV DANIEL ,  KAUS MICHAEL

Inventor： PEKAR VLADIMIR ,  BYSTROV DANIEL ,  KAUS MICHAEL

IPC: G06T7/00

CPC classification number: G06T7/32 ,  G06T2207/10081 ,  G06T2207/30004

Abstract: The present invention aims at improving the point-based elastic registration paradigm. According to the present invention, a force field, for example, with Gaussian-shaped forces, is applied at several points to the image to be deformed. In this case, no landmark correspondences are required and the optimal positions of the force application point are found automatically, which minimizes the différence between the source and target image. Advantageously, this may allow to control a local influence of individual control points.

Abstract translation: 本发明旨在改进基于点的弹性注册范例。 根据本发明，例如具有高斯形力的力场在几个点处被施加到待变形的图像。 在这种情况下，不需要具有里程碑式的对应关系，并且自动找到力施加点的最佳位置，这最小化了源图像和目标图像之间的差异。 有利的是，这可以允许控制各个控制点的局部影响。

公开(公告)号：WO2010113050A3

公开(公告)日：2010-12-02

申请号：PCT/IB2010050893

申请日：2010-03-02

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  PEKAR VLADIMIR ,  BYSTROV DANIEL

Inventor： PEKAR VLADIMIR ,  BYSTROV DANIEL

IPC: G06F19/00 ,  A61N5/10

CPC classification number: A61N5/103 ,  G06F19/3481

Abstract: When delineating anatomical structures in a medical image of a patient for radiotherapy planning, a processor (18) detects landmarks (24) in a low-resolution image (e.g., MRI or low-dose CT) and maps the detected landmarks to reference landmarks (28) in a reference contour of the anatomical structure. The mapped landmarks facilitate adjusting the reference contour to fit the anatomical structure. The adjusted reference contour data is transformed and applied to a second image using a thin-plate spline, and the adjusted high-resolution image is used for radiotherapy planning.

Abstract translation: 当在放射治疗计划的患者的医疗图像中描绘解剖结构时，处理器（18）检测低分辨率图像（例如，MRI或低剂量CT）中的界标（24），并将检测到的界标映射到参考界标 28）在解剖结构的参考轮廓中。 映射的界标便于调整参考轮廓以适应解剖结构。 调整后的参考轮廓数据被转换并且使用薄板样条线应用于第二图像，并且调整后的高分辨率图像用于放射治疗计划。

公开(公告)号：WO2009016530A2

公开(公告)日：2009-02-05

申请号：PCT/IB2008052812

申请日：2008-07-11

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  PEKAR VLADIMIR ,  VIK TORBJOERN ,  SCHULZ HEINRICH ,  JAFFRAY DAVID

Inventor： PEKAR VLADIMIR ,  VIK TORBJOERN ,  SCHULZ HEINRICH ,  JAFFRAY DAVID

IPC: G06T7/00

CPC classification number: G06Q50/22 ,  G06T7/12 ,  G06T7/149 ,  G06T7/33 ,  G06T19/00 ,  G06T2200/24 ,  G06T2207/20101 ,  G06T2207/30004 ,  G06T2210/41

Abstract: When modeling anatomical structures in a patient for diagnosis or therapeutic planning, an atlas (26) of predesigned anatomical structure models can be accessed, and model of one or more such structures can be selected and overlaid on an a 3D image of corresponding structure(s) in a clinic image of a patient. A user can click and drag a cursor on the model to deform the model to align with the clinical image. Additionally, a processor (16) can generate a volumetric deformation function using splines, parametric techniques, or the like, and can deform the model to fit the image in real time, in response to user manipulation of the model.

Abstract translation: 当对病人的解剖结构进行建模以进行诊断或治疗计划时，可以访问预先设计的解剖结构模型的图集（26），并且可以选择一个或多个这样的结构的模型并覆盖在对应结构的3D图像上 ）在患者的诊所图像中。 用户可以单击并拖动模型上的光标，使模型变形以与临床图像对齐。 另外，处理器（16）可以使用样条曲线，参数技术等来产生体积变形函数，并且可以响应于模型的用户操纵而实时变形模型以适合图像。

公开(公告)号：WO2007133932A3

公开(公告)日：2009-01-15

申请号：PCT/US2007067846

申请日：2007-05-01

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS CORP ,  PHILIPS INTELLECTUAL PROPERTY ,  KAUS MICHAEL ,  PEKAR VLADIMIR ,  WIEMKER RAFAEL

Inventor： KAUS MICHAEL ,  PEKAR VLADIMIR ,  WIEMKER RAFAEL

IPC: G06T7/00

CPC classification number: A61N5/103 ,  A61B5/7285 ,  A61B6/03 ,  A61B6/466 ,  A61B6/541 ,  A61B8/543 ,  A61N5/1037 ,  A61N2005/1061 ,  G06F19/321 ,  G06F19/3437 ,  G06F19/3481 ,  G06Q50/22 ,  G06T7/33 ,  G06T7/38 ,  G06T2207/30004 ,  G16H50/50

Abstract: A system and method for developing radiation therapy plans and a system and method for developing a radiation therapy plan to be used in a radiation therapy treatment is disclosed. A radiation therapy plan is developed using a registration of medical images. The registration is based on identifying landmarks located within inner body structures.

Abstract translation: 公开了一种用于制定放射治疗计划的系统和方法以及用于制定放射疗法治疗中使用的放射治疗计划的系统和方法。 使用医学图像的注册开发放射治疗计划。 注册基于识别位于内部身体结构内的地标。

公开(公告)号：WO2008007281A3

公开(公告)日：2008-06-19

申请号：PCT/IB2007052505

申请日：2007-06-28

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  BYSTROV DANIEL ,  PEKAR VLADIMIR ,  YOUNG STEWART ,  BERGMANS CORNELIS J F M ,  VAN MUISWINKEL ARIANNE

Inventor： BYSTROV DANIEL ,  PEKAR VLADIMIR ,  YOUNG STEWART ,  BERGMANS CORNELIS J F M ,  VAN MUISWINKEL ARIANNE

IPC: G06T7/00 ,  G01R33/54

CPC classification number: G01R33/54 ,  G01R33/543 ,  G06T7/74 ,  G06T2207/30004 ,  G06T2207/30244

Abstract: The invention relates to a method, an apparatus and a computer program for transferring scan geometry between a first region and a second region, similar to the first region. In the method according to the invention the first region and the second region are being identified (4), preferably in the overview image, followed by determination (6) of the first scan geometry corresponding to the first region. Then, the first scan geometry is being transferred into the second scan geometry corresponding to the second region, whereby information on geometrical correspondence between the first region and the second region is used. Preferably, the step of transferring comprises establishing corresponding mappings between similar regions and their respective scan geometries.

Abstract translation: 本发明涉及用于在第一区域和第二区域之间传送扫描几何的方法，装置和计算机程序，类似于第一区域。 在根据本发明的方法中，优选地在概览图像中识别（4）第一区域和第二区域，随后确定（6）对应于第一区域的第一扫描几何图形。 然后，将第一扫描几何图形转移到对应于第二区域的第二扫描几何图形中，由此使用关于第一区域和第二区域之间的几何对应关系的信息。 优选地，转移步骤包括在相似区域和它们各自的扫描几何结构之间建立对应的映射。

公开(公告)号：WO2006134565A3

公开(公告)日：2007-02-22

申请号：PCT/IB2006051906

申请日：2006-06-14

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  PEKAR VLADIMIR ,  CARLSEN INGWER-CURT

Inventor： PEKAR VLADIMIR ,  CARLSEN INGWER-CURT

IPC: G06T3/00 ,  G06T7/00

CPC classification number: G06T3/0081 ,  G06T7/33 ,  G06T2207/30004

Abstract: The invention aims at improving the point-based elastic registration paradigm. Point-based elastic registration is typically carried out by finding corresponding point landmarks (2, 4) in both images and using the point correspondences as constraints to interpolate the global displacement field. A limitation of this approach is that it only ensures the correspondences between structures where point landmarks (2, 4) can be identified. Alternative concepts are limited by high computational costs for optimization. The concept of the invention provides a method and a system (1) wherein additional deformation field constraints are imposed by: partitioning (PART (I S , I T )) one or more restricted structures corresponding in the first (3) and the second (5) image and imposing additional constraints ( Add

Abstract translation: 本发明旨在改进基于点的弹性登记范例。 基于点的弹性配准通常通过在两个图像中找到对应的点地标（2,4）并且使用点对应作为内插全局位移场的约束来执行。 这种方法的局限性在于，它只能确保可以识别点地标（2,4）的结构之间的对应关系。 替代的概念受到优化的高计算成本的限制。 本发明的概念提供了一种方法和系统（1），其中通过以下方式来施加附加的变形场约束：一个或多个分割（一个或多个） 在第一（3）和第二（5）图像中对应的更受限制的结构并且施加附加约束（^添加

公开(公告)号：WO2004109580A3

公开(公告)日：2005-03-24

申请号：PCT/IB2004050805

申请日：2004-05-28

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  WIEMKER RAFAEL ,  BLAFFERT THOMAS ,  PEKAR VLADIMIR

Inventor： WIEMKER RAFAEL ,  BLAFFERT THOMAS ,  PEKAR VLADIMIR

IPC: G06T7/00 ,  G06F19/00

CPC classification number: G06T7/0012

Abstract: Ground glass opacities in the lung are non-solid nebular-like shadows in the parenchyma tissue of the lung, which may be precursors of a lung cancer. According to the present invention, ground glass opacities may automatically be determined on the basis of a texture analysis of the parenchyma. Advantageously, according to the present invention, a robust and reliable determination of ground glass opacities may be provided, even if vessels, lung walls, airspace or bronchi walls are present within the local neighborhood of the ground glass opacity.

Abstract translation: 肺中的玻璃不透明度是肺实质组织中非固体的星状样阴影，可能是肺癌的前体。 根据本发明，可以根据实质的纹理分析自动确定研磨玻璃的不透明度。 有利地，根据本发明，即使在玻璃不透明度的局部邻域内存在容器，肺壁，空气或支气管壁，也可以提供坚实可靠的磨玻璃不透明度测定。