公开(公告)号：AU2013230425A1

公开(公告)日：2014-09-18

申请号：AU2013230425

申请日：2013-03-05

Applicant: REDDYS LAB LTD DR

Inventor： SASMAL PRADIP KUMAR ,  VAMSEEKRISHNA CHINTAKUNTA ,  POTLURI VIJAY ,  TEHIM ASHOK ,  GAI YONGHUA ,  ZHANG HANG

IPC: C07D207/12 ,  A61K31/40 ,  C07D207/04 ,  C07D217/12

Abstract: The present invention relates to a series of substituted compounds having the general formula (I), including their ste reoisomers and/or their pharmaceutically acceptable salts, wherein R

公开(公告)号：CA2866299A1

公开(公告)日：2013-09-12

申请号：CA2866299

申请日：2013-03-05

Applicant: REDDYS LAB LTD DR

Inventor： SASMAL PRADIP KUMAR ,  VAMSEEKRISHNA CHINTAKUNTA ,  POTLURI VIJAY ,  TEHIM ASHOK ,  GAI YONGHUA ,  ZHANG HANG

IPC: C07D207/12 ,  A61K31/40 ,  C07D207/04 ,  C07D217/12

Abstract: The present invention relates to a series of substituted compounds having the general formula (I), including their ste reoisomers and/or their pharmaceutically acceptable salts, wherein R1, R2, R3. R4, R5, and R6 are as defined herein. This invention also relates to methods of making these compounds including intermediates. The compounds of this invention are effective at the kappa (?) opioid receptor (KOR) site. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic pain, and associated disorders, particularly functioning peripherally at the CNS.

公开(公告)号：CA2614098A1

公开(公告)日：2007-01-11

申请号：CA2614098

申请日：2006-06-30

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB INC DR

Inventor： DAS SAIBAL KUMAR ,  TALWAR RASHMI ,  POTLURI VIJAY KUMAR ,  IQBAL JAVED ,  CHAKRABARTI RANJAN ,  SASMAL PRADIP KUMAR ,  MISRA PARIMAL

IPC: C07D277/14 ,  A61K31/426 ,  A61K31/5377 ,  C07D265/32

公开(公告)号：AU2012351748A1

公开(公告)日：2014-07-17

申请号：AU2012351748

申请日：2012-12-12

Applicant: REDDYS LAB LTD DR

Inventor： SASMAL PRADIP KUMAR ,  AHMED SHAHADAT ,  TEHIM ASHOK ,  PRADKAR VIDYADHAR ,  DATTATREYA PRASANNA M ,  MAVINAHALLI NANJEGOWDA JAGADEESH

IPC: C07D471/04 ,  A61K31/437 ,  A61P29/00 ,  A61P35/00

Abstract: The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors., method of making and pharmaceutical compositions comprising such compounds.

公开(公告)号：CA2858958A1

公开(公告)日：2013-06-20

申请号：CA2858958

申请日：2012-12-12

Applicant: REDDYS LAB LTD DR

Inventor： SASMAL PRADIP KUMAR ,  AHMED SHAHADAT ,  TEHIM ASHOK ,  PARADKAR VIDYADHAR ,  DATTATREYA PRASANNA M ,  MAVINAHALLI NANJEGOWDA JAGADEESH

IPC: C07D471/04 ,  A61K31/437 ,  A61P29/00 ,  A61P35/00

Abstract: The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors., method of making and pharmaceutical compositions comprising such compounds.