公开(公告)号：CA3113377A1

公开(公告)日：2020-04-16

申请号：CA3113377

申请日：2018-10-11

Applicant: SANIFIT THERAPEUTICS S A

Inventor： PERELLO BESTARD JOAN ,  SALCEDO ROCA CAROLINA ,  CANALS HAMANN ANA-ZERALDA

IPC: A61K31/6615 ,  A61K9/00 ,  A61K31/661 ,  A61K45/06 ,  A61P17/02 ,  A61P43/00

Abstract: The present disclosure related to compositions, methods, dosages, dosage regimens, articles of manufacture and kits for the treatment and/or prevention ectopic calcifications, and in particular cutaneous calcifications such as calciphylaxis calcifications comprising inositol phosphate, inositol phosphate analogs, inositol phosphate derivatives, or combinations thereof. In a particular aspect the disclosure provides a dosage regimen to treat calciphylaxis comprising the administration of 6 mg/kg to 9 mg/kg daily doses of myo-inositol hexaphosphate, three times a week, for at least 1 to 8 months.