Abstract:
Disclosed is a sample analyzer, comprising: an illuminator; a support positioned to support a sample vessel containing an assay sample proximate the illuminator, such that the illuminator causes luminescence of the assay sample; a detector positioned along an optical axis extending from the illuminator, through the assay sample, to the detector, so as to detect luminescence of the assay sample; a shuttle disposed between the illuminator and the assay sample; and a reflector disposed on the shuttle. The apparatus is configured with an illumination mode and a measurement mode, wherein during the illumination mode the shuttle positions the reflector off the optical axis, and the illuminator is operated to illuminate the assay sample, wherein during the measurement mode the shuttle positions the reflector onto the optical axis such that luminescence from the assay sample is reflected off the reflector back through the assay sample towards the detector along the optical axis. Further disclosed is a method of analyzing an assay sample, using the sample analyzer.
Abstract:
A shutter assembly includes a first shutter blade having a first toothed arm extending therefrom and a first light transmitting aperture therein, and a second shutter blade positioned adjacent and parallel to the first shutter blade. The second shutter blade has a second toothed arm extending therefrom and a second light transmitting aperture therein. The first and second shutter blades are supported to allow parallel linear motion. A motor gear is disposed between, and meshed with, the first and second toothed arms such that rotation of the gear causes the first and second shutter blades to move linearly in opposite directions between an open position in which the first and second light transmitting apertures are in an overlapping relationship with respect to one another, and a closed position in which the first and second light transmitting apertures are in a non-overlapping relationship with respect to one another.