公开(公告)号：EP3648817A1

公开(公告)日：2020-05-13

申请号：EP18734571.5

申请日：2018-07-03

Applicant: Stamford Devices Limited

Inventor： MACLOUGHLIN, Ronan ,  PORTER, Shaun ,  DUFFY, Conor ,  POWER, John

IPC: A61M11/00 ,  A61M15/08 ,  A61M16/14 ,  A61M16/16

公开(公告)号：EP4309718A3

公开(公告)日：2024-03-27

申请号：EP23213965.9

申请日：2018-07-03

Applicant: Stamford Devices Limited

Inventor： MACLOUGHLIN, Ronan ,  PORTER, Shaun ,  DUFFY, Conor ,  POWER, John

IPC: A61M11/00 ,  A61M15/08 ,  A61M16/14 ,  A61M16/16 ,  A61M11/02 ,  A61M16/00 ,  A61M16/06

Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

公开(公告)号：EP3275491A1

公开(公告)日：2018-01-31

申请号：EP17187340.9

申请日：2015-04-10

Applicant: Stamford Devices Limited

Inventor： MACLOUGHLIN, Ronan ,  SMITH, Niall

IPC: A61M11/00 ,  A61M15/00 ,  A61M16/00 ,  A61M16/06 ,  A61M16/10 ,  A61M16/14 ,  A61M16/16 ,  A61M16/08 ,  A61M16/20 ,  A61M15/08

CPC classification number: A61M16/16 ,  A61M11/00 ,  A61M15/08 ,  A61M16/0666 ,  A61M16/0833 ,  A61M16/0866 ,  A61M16/0875 ,  A61M16/1095 ,  A61M16/14 ,  A61M16/202 ,  A61M2016/0018 ,  A61M2016/0027 ,  A61M2016/0033 ,  A61M2016/0036 ,  A61M2205/33 ,  A61M2205/3334

Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.

Abstract translation: 高流量鼻部治疗系统（1）具有气体供应装置（2），雾化器（12）和鼻界面（7）。 有两个分支（11,10）和与控制器连接的阀（6），分支包括用于输送气溶胶的第一分支（11）和用于输送非雾化气体的第二分支（10）。 控制器控制输送到分支（11,10）中，其中第一和第二分支中的流动是单向的，从气体供应朝向鼻界面。 第一分支（11）包括雾化器（12）以及构造成在流过第二分支（10）期间存储气雾团的线。 阀（6）包括在一侧的气体入口和另一侧的分支之间的Y形接头。

公开(公告)号：EP3129086A1

公开(公告)日：2017-02-15

申请号：EP15713953.6

申请日：2015-04-10

Applicant: Stamford Devices Limited

Inventor： MACLOUGHLIN, Ronan ,  SMITH, Niall

IPC: A61M11/00 ,  A61M15/00 ,  A61M16/00 ,  A61M16/06 ,  A61M16/10 ,  A61M16/14 ,  A61M16/16 ,  A61M16/08 ,  A61M16/20 ,  A61M15/08

CPC classification number: A61M16/16 ,  A61M11/00 ,  A61M15/08 ,  A61M16/0666 ,  A61M16/0833 ,  A61M16/0866 ,  A61M16/0875 ,  A61M16/1095 ,  A61M16/14 ,  A61M16/202 ,  A61M2016/0018 ,  A61M2016/0027 ,  A61M2016/0033 ,  A61M2016/0036 ,  A61M2205/33 ,  A61M2205/3334

Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.

Abstract translation: 高流量鼻腔治疗系统（1）具有气体供应（2），雾化器（12）和鼻腔接口（7）。 有两个分支（11,10）和与控制器连接的阀（6），分支包括用于输送气溶胶的第一分支（11）和用于输送非气雾化气体的第二分支（10）。 控制器控制从气体供应朝向鼻部界面的分支（11,10）中的输送，其中流动在第一和第二分支中是单向的。 第一分支（11）包括雾化器（12）和配置成在通过第二分支（10）的流动期间存储气溶胶团的管线。 阀（6）包括在一侧的气体入口与另一侧的分支之间的Y形结。

公开(公告)号：EP4215233A1

公开(公告)日：2023-07-26

申请号：EP23162159.0

申请日：2018-07-03

Applicant: Stamford Devices Limited

Inventor： MACLOUGHLIN, Ronan ,  PORTER, Shaun ,  DUFFY, Conor ,  POWER, John

IPC: A61M11/00 ,  A61M15/08 ,  A61M16/14 ,  A61M16/16

Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

公开(公告)号：EP3922362A1

公开(公告)日：2021-12-15

申请号：EP21181812.5

申请日：2016-06-10

Applicant: Stamford Devices Limited

Inventor： MACLOUGHLIN, Ronan ,  DUFFY, Conor ,  HOGAN, Brendan ,  KELLY, Patrick Martin

IPC: B05B17/00

Abstract: A method for aerosolising a liquid comprises the steps of providing an aperture plate having at least 100 outlet holes per mm 2 ; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 tol5 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.

公开(公告)号：EP3275491B1

公开(公告)日：2020-12-02

申请号：EP17187340.9

申请日：2015-04-10

Applicant: Stamford Devices Limited

Inventor： MACLOUGHLIN, Ronan ,  SMITH, Niall

IPC: A61M16/06 ,  A61M16/16

公开(公告)号：EP3307442A1

公开(公告)日：2018-04-18

申请号：EP16732528.1

申请日：2016-06-10

Applicant: Stamford Devices Limited

Inventor： MACLOUGHLIN, Ronan ,  DUFFY, Conor ,  HOGAN, Brendan ,  KELLY, Patrick Martin

IPC: B05B17/00

CPC classification number: B05B17/0646

Abstract: A method for aerosolising a liquid comprises the steps of:—providing an aperture plate having at least 100 outlet holes per mm2; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 to 15 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.