Abstract:
Provided are magnetic particles for nucleic acid sequencing and a method of sequencing nucleic acid using the same. The nucleotide sequence of a target nucleic acid may be efficiently determined using the magnetic particles and the method of sequencing nucleic acid using the same.
Abstract:
An apparatus for focusing a particle in a sheath flow, the apparatus comprising: a sheath fluid inlet for injecting a sheath fluid; a first flow channel for conveying a fluid, wherein the first flow channel extends from the sheath fluid inlet to the fluid outlet and is formed such that a channel extending from the sheath fluid inlet is divided into two subchannels that extend further and are then merged into one channel; and a second flow channel that extends from the sample fluid inlet to the sample fluid outlet, wherein the second flow channel is in fluid communication with the first flow channel at the merged channel region through the sample fluid outlet so as to introduce a particle in a sample into a sheath fluid conveyed through the first flow channel.
Abstract:
A multi-channel fluorescence measuring optical system and a multi-channel fluorescence sample analyzer using the optical system are provided. The multi-channel fluorescence measuring optical system, which irradiates light onto a plurality of sample channels and detecting fluorescence radiated from samples, includes: a light source (60a-d); an integrator (70) for giving the light irradiated from the light source a uniform intensity distribution; a sample holder (80) having a plurality of sample channels on which the samples (m) are mounted, wherein the samples are exited by the light emitted from the integrator; and a beam splitter (75) between the integrator and the sample holder for dividing the incident light in a predetermined ratio. Since the light intensities of fluorescence images are detected using optical fiber bundles (85a-d) and photodiodes (89a-d), the manufacturing cost can be greatly reduced, and the optical system can be miniaturized.