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公开(公告)号：CA2719356A1
公开(公告)日：2009-10-08
申请号：CA2719356
申请日：2009-03-30
Applicant: TORAY INDUSTRIES
Inventor： UENO YOSHIYUKI , FUJITA MASAKI , SUGAYA HIROYUKI
Abstract: Provided is a separation membrane module suffering from little sticking of organic matters, proteins, platelets and so on. A separation membrane which is a membrane comprising a polymer, characterized in that a functional layer is formed on the surface in one side of the membrane, the peak area percentage of carbon derived from ester group measured by the electron spectroscopy for chemical analysis (ESCA) on the surface of the preceding functional layer is 0.1% (by atomic number) or more but not more than 10 (% by atomic number), and the peak area percentage of carbon derived from ester group measured by the electron spectroscopy for chemical analysis (ESCA) on the surface opposite to the functional layer is not more than 10 (% by atomic number); and a separation membrane module provided with the same as a built-in membrane.
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公开(公告)号：AU2014355438B2
公开(公告)日：2018-08-30
申请号：AU2014355438
申请日：2014-11-27
Applicant: TORAY INDUSTRIES
Inventor： TSUCHIKURA HIROSHI , YAMADA SATOSHI , FUJITA MASAKI , KUWABARA ATSUSHI
Abstract: Provided is a multiple tubular woven structure with which a fluid or powder can be carried without any problems, and which can be suitably used in the application of a hose for protecting linear objects such as wires, cables, hoses, and electric conduits. This multiple tubular woven structure has two or more layers. A monofilament is used in the weft forming a layer (A), where said layer (A) is not the innermost layer. Said weft is wound in a spiral configuration, and the interval between adjacent weft-forming monofilaments is longer than the monofilament diameter.
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公开(公告)号：CA2821486C
公开(公告)日：2018-07-24
申请号：CA2821486
申请日：2011-12-19
Applicant: TORAY INDUSTRIES
Inventor： YAMAMURA YASUFUMI , TANAHASHI KAZUHIRO , NAKANISHI MEGUMI , FUJITA MASAKI
Abstract: The present invention aims to provide biodegradable particles for medical use and a vascular embolization material which have improved flexibility, cause less aggregation among particles, and have improved particle shape-recovering ability after passing through a catheter or the like. The present invention provides biodegradable particles for medical use composed of an A1-B-A2 type triblock copolymer, wherein A1 and A2 are each a block of biodegradable copolymer constituted by monomers comprising glycolic acid, lactic acid and 6-hydroxycaproic acid, and B is a block of water-soluble polymer.
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公开(公告)号：AU2016267435A1
公开(公告)日：2017-12-07
申请号：AU2016267435
申请日：2016-05-27
Applicant: TORAY INDUSTRIES
Inventor： KADOWAKI KOJI , SAITO AKIHIRO , NAKANISHI MEGUMI , FUJITA MASAKI , TANAHASHI KAZUHIRO
IPC: A61L33/00
Abstract: The purpose of the present invention is to provide an antithrombotic material which exhibits high antithrombotic activity that is sustained over a long period, while reducing the thickness of the coating material. The present invention is an antithrombotic material comprising a coating material containing a compound having anionic anti-clotting activity and including sulfur atoms together with a cationic polymer containing, as a constituent monomer, a compound selected from the group consisting of alkylene imine, vinyl amine, allyl amine, lysine, protamine and diallyl dimethyl ammonium chloride, and a substrate having the surface thereof coated by said coating material, wherein the cationic polymer is covalently bonded to the substrate, and the compound having anionic anticoagulant activity and including sulfur atoms is immobilized on the substrate surface by ionic bonding with the cationic polymer, and the average thickness of the coating material is 15-400nm.
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公开(公告)号：CA2866281C
公开(公告)日：2016-11-01
申请号：CA2866281
申请日：2013-03-28
Applicant: TORAY INDUSTRIES
Inventor： FUJITA MASAKI , NAKANISHI MEGUMI , TANAHASHI KAZUHIRO
IPC: A61L31/00 , A61L15/64 , A61L17/00 , C08G63/06 , C08L101/16
Abstract: The present invention aims to provide a biodegradable material having an enhanced shape recovery rate after deformation of the material and an improved flexibility. The present invention provides a biodegradable material which is a chemically cross-linked product between a multivalent compound A having 3 or more functional groups X such as hydroxyl group; and a multivalent compound B having 3 or more functional groups Y such as carboxyl group wherein chemical cross-linkage(s) is/are formed by condensation reaction of the functional group(s) X and the functional group(s) Y; wherein the value of (y + z)/(x + z) is 1.2 to 4.0 when MA >= MB, and the value of (x + z)/(y + z) is 1.2 to 4.0 when MA
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Patent Agency Ranking
公开(公告)号：CA2979779A1
公开(公告)日：2016-10-06
申请号：CA2979779
申请日：2016-03-31
Applicant: TORAY INDUSTRIES
Inventor： KADOWAKI KOJI , FUJITA MASAKI , SAKAGUCHI YUKA , TANAHASHI KAZUHIRO
Abstract: The present invention addresses the problem of providing an antithrombotic metallic material which has improved safety against low hemolytic toxicity and can exhibit high antithrombotic properties sustainably. The present invention provides an antithrombotic metallic material comprising a metallic material of which the surface is coated with a coating material, wherein the coating material comprises a phosphonic acid derivative or a catechol derivative, a polymer containing, as a constituent monomer, a compound selected from the group consisting of an alkyleneimine, vinylamine, allylamine, lysine, protamine and diallyl dimethyl ammonium chloride and a sulfur-atom-containing compound having an anionic anticoagulant activity, the polymer is covalently bonded to the phosphonic acid derivative or the catechol derivative, the phosphonic acid derivative or the catechol derivative is bonded to the metallic material through a phosphonic acid group or a catechol group contained in the derivative, and the ratio of the amount of nitrogen atoms to the total amount of all of atoms is 4.0 to 13.0% by atom number when the surface of the antithrombotic metallic material is measured by an X-ray photoelectron spectroscopy (XPS).
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公开(公告)号：CA2823013C
公开(公告)日：2016-09-20
申请号：CA2823013
申请日：2011-12-27
Applicant: TORAY INDUSTRIES
Inventor： UENO YOSHIYUKI , FUJITA MASAKI , SUGAYA HIROYUKI , HASHIMOTO KAZUYUKI , TERASAKA HIROYUKI , KOGANEMARU RYO
Abstract: The purpose of the invention of the present application is to provide a medical material and a blood purification apparatus each having high anti-thrombotic properties and high safety. The apparatus is produced by incorporating therein a medical material which has a hydrophilic copolymerization polymer present on a surface thereof which is to be in contact with blood, wherein particulate protuberances each having a particle diameter of 50 nm or more are present on the surface which is to be in contact with blood at a density of 3 particles/µm2 or less and the relaxation time of adsorbed water in the hydrophilic copolymerization polymer is 2.5 × 10 -8 seconds or shorter and 5.0 × 10 -10 seconds or longer at -40°C.
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公开(公告)号：CA2965281A1
公开(公告)日：2016-05-06
申请号：CA2965281
申请日：2015-10-30
Applicant: TORAY INDUSTRIES
Inventor： KADOWAKI KOJI , KUGA CHISA , FUJITA MASAKI , TANAHASHI KAZUHIRO , YAMADA SATOSHI , KANEKO TAKAYUKI , TSUCHIKURA HIROSHI
Abstract: The purpose of the present invention is to provide a fiber structure for use as a cell scaffold material having both improved cell adhesiveness and improved cell proliferation by controlling physical properties, namely the orientation and the average fiber diameter of a fiber in a multifilament. The present invention provides a fiber structure for use as a cell scaffold material which includes a multifilament formed by bundling single fibers having an average fiber diameter of 1-15 µm and in which the single fibers satisfy the condition of formula 1. (Y/X) × 100 = 50···formula 1. [In formula 1, X represents the number of single fibers the average intersection angle of which is examined and Y represents the number of single fibers, among X, the average intersection angle of which is 25° or less.]
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公开(公告)号：CA2929366A1
公开(公告)日：2015-06-04
申请号：CA2929366
申请日：2014-11-27
Applicant: TORAY INDUSTRIES
Inventor： TSUCHIKURA HIROSHI , YAMADA SATOSHI , FUJITA MASAKI , KUWABARA ATSUSHI
Abstract: Provided is a multiple tubular woven structure with which a fluid or powder can be carried without any problems, and which can be suitably used in the application of a hose for protecting linear objects such as wires, cables, hoses, and electric conduits. This multiple tubular woven structure has two or more layers. A monofilament is used in the weft forming a layer (A), where said layer (A) is not the innermost layer. Said weft is wound in a spiral configuration, and the interval between adjacent weft-forming monofilaments is longer than the monofilament diameter.
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公开(公告)号：CA2823013A1
公开(公告)日：2012-07-05
申请号：CA2823013
申请日：2011-12-27
Applicant: TORAY INDUSTRIES
Inventor： UENO YOSHIYUKI , FUJITA MASAKI , SUGAYA HIROYUKI , HASHIMOTO KAZUYUKI , TERASAKA HIROYUKI , KOGANEMARU RYO
Abstract: The invention addresses the problem of providing a medical material and a hemoperfusion machine of high anti-thrombotic properties and safety. The machine is obtained by incorporating a medical material, wherein: a hydrophilic copolymer is present on the surface contacting the blood; 3/µm2 or less of particulate protuberances of 50 nm or higher particle diameter are present on said blood-contacting surface; and the relaxation time at -40°C of water adsorbed to the hydrophilic copolymer is 5.0 x 10-10 seconds to 2.5 x 10-8 seconds.
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