公开(公告)号：AU2017305070B2

公开(公告)日：2022-03-10

申请号：AU2017305070

申请日：2017-08-04

Applicant: TORAY INDUSTRIES

Inventor： BABA TAKESHI ,  KAWAKAMI TOMONORI ,  USHIRO SUGURU ,  UENO YOSHIYUKI

IPC: C08F218/04 ,  A61L33/06 ,  A61M1/16 ,  B01D71/38 ,  B01D71/40 ,  B01D71/44 ,  C08F220/12 ,  C08F226/02 ,  C08F226/10

Abstract: The purpose of the present invention is to provide a copolymer having exceptional water permeability, platelet adherence suppression, and protein adherence suppression, and to provide a separation membrane, a medical device, and a medical separation membrane module in which said copolymer is used. The present invention provides a copolymer containing monomer units derived from two or more types of monomer, wherein the hydration energy density of the copolymer is 158.992 to 209.200 kJ・mol

公开(公告)号：RU2757274C2

公开(公告)日：2021-10-12

申请号：RU2019110782

申请日：2017-09-20

Applicant: TORAY INDUSTRIES

Inventor： USHIRO SUGURU ,  HAYASHI AKIHIRO ,  UENO YOSHIYUKI

IPC: C08F226/06 ,  A61B17/221 ,  A61L31/04 ,  A61L33/06 ,  C08F218/04 ,  C08F220/32 ,  C08F220/36 ,  C08F226/10

Abstract: Настоящееизобретениеотноситсяк сополимеру, медицинскомуматериалу, устройствузахватакровии конторуциркуляциикрови. Данныйсополимерсодержитмономерноезвено A, мономерноезвено B имономерноезвено C общейформулы:. Молярнаяфракциямономерногозвена C наосновевсехмономерныхзвеньев, которыеобразуютсополимер, составляетот 0,5 до 40%. Медицинскийматериалсодержитданныйсополимери материалосновы, связанныйс сополимером. Материалосновывыполненизполимераилиметалла. Техническийрезультат– разработкасополимера, которыйможноиммобилизоватьнаматериалеосновы, приэтомсохраняясильныеантитромботическиесвойствапостояннобезнеобходимостивведениягепаринаилиантикоагулянтноголекарственногосредстванаповерхностьматериалаосновы. 4 н. и 7 з.п. ф-лы, 3 ил., 3 табл., 19 пр.

公开(公告)号：SG11202010151SA

公开(公告)日：2020-11-27

申请号：SG11202010151S

申请日：2019-05-24

Applicant: TORAY INDUSTRIES

Inventor： HAYASHI AKIHIRO ,  AKAIKE KAORI ,  USHIRO SUGURU ,  UENO YOSHIYUKI

IPC: B01D69/08 ,  B01D69/00 ,  B01D71/40 ,  B01D71/68 ,  C08J9/26 ,  C08J9/42

Abstract: Disclosed is a porous hollow fiber membrane containing a polysulfone-based polymer as a main component, which has an asymmetric structure in which the inner surface side is dense and the outer surface side is coarse, wherein an average of a minor axis diameter of pores of an inner surface is 20 nm or more and 40 nm or less, an open porosity of the inner surface is 10% or more and 30% or less, and a polymer including a monocarboxylic acid vinyl ester unit is supported on at least one of the outer surface and the inner surface. The present invention provides a hollow fiber membrane which has excellent removing performance of substances to be separated such as viruses, and can be used as a separation membrane having high permeability even in a treatment under low pressure.

公开(公告)号：ES2751578T3

公开(公告)日：2020-04-01

申请号：ES16772271

申请日：2016-03-15

Applicant: TORAY INDUSTRIES

Inventor： USHIRO SUGURU ,  TAKAHASHI HIROSHI ,  UENO YOSHIYUKI

IPC: A61K35/16 ,  C08F218/10 ,  A61L33/06 ,  B01D69/06 ,  B01D69/08 ,  B01D71/44 ,  B01D71/68 ,  C08F226/10

Abstract: Dispositivo médico que comprende un copolímero que comprende una unidad hidrófila y una unidad hidrófoba, en el que la unidad hidrófoba incluye, como mínimo, una unidad de carboxilato de vinilo, la unidad de carboxilato de vinilo tiene 2 o más y 7 o menos átomos de carbono en un extremo de la cadena lateral de la misma, y en el que el dispositivo médico comprende el copolímero introducido, como mínimo, en una parte de una superficie del mismo que está en contacto con un componente biológico.

公开(公告)号：AU2017307699A1

公开(公告)日：2019-01-17

申请号：AU2017307699

申请日：2017-07-28

Applicant: TORAY INDUSTRIES

Inventor： USHIRO SUGURU ,  HAYASHI AKIHIRO ,  UENO YOSHIYUKI

IPC: A61M1/16 ,  A61L33/00 ,  B01D69/12

Abstract: The purpose of the present invention is to provide a biological component adhesion-suppressing material that is able to suppress adhesion of platelets and proteins even when coming into contact with blood, etc. The present invention comprises a substrate which is provided with a functional layer having, fixed on a surface thereof that comes into contact with a biological component, a polymer including a saturated aliphatic monocarboxylic acid vinyl ester unit, wherein: when compositional analysis is performed on the surface of the functional layer using a TOF-SIMS device, the number of carbon atoms in an aliphatic chain representing an ion signal detected for saturated aliphatic carboxylic acid is 2-20; and an XPS measurement taken of the surface of the functional layer shows a peak derived from an ester group.

公开(公告)号：AU2017305070A1

公开(公告)日：2019-01-17

申请号：AU2017305070

申请日：2017-08-04

Applicant: TORAY INDUSTRIES

Inventor： KAWAKAMI TOMONORI ,  USHIRO SUGURU ,  UENO YOSHIYUKI ,  BABA TAKESHI

IPC: C08F218/04 ,  A61L33/06 ,  A61M1/16 ,  B01D71/38 ,  B01D71/40 ,  B01D71/44 ,  C08F220/12 ,  C08F226/02 ,  C08F226/10

Abstract: The purpose of the present invention is to provide a copolymer having exceptional water permeability, platelet adherence suppression, and protein adherence suppression, and to provide a separation membrane, a medical device, and a medical separation membrane module in which said copolymer is used. The present invention provides a copolymer containing monomer units derived from two or more types of monomer, wherein the hydration energy density of the copolymer is 158.992 to 209.200 kJ・mol

公开(公告)号：CA2975588A1

公开(公告)日：2016-10-06

申请号：CA2975588

申请日：2016-03-15

Applicant: TORAY INDUSTRIES

Inventor： USHIRO SUGURU ,  TAKAHASHI HIROSHI ,  UENO YOSHIYUKI

IPC: C08F218/04 ,  A61K35/16 ,  A61L31/00 ,  A61L33/00 ,  A61M1/18 ,  B01D69/10 ,  B01D69/12 ,  B01D71/38 ,  B01D71/44 ,  B01D71/68 ,  C08F226/10

Abstract: The purpose of the present invention is to provide: a copolymer having blood compatibility and antithrombotic properties of greatly suppressing protein adhesion so as to be usable even when being in contact with a biological component such as blood for a long period of time; and a medical device using the copolymer. In order to achieve the purpose, the present invention has the following configuration. Specifically, the copolymer is characterized by including a hydrophilic unit and a hydrophobic unit, wherein the hydrophobic unit contains at least one type of a carboxylic acid vinyl unit, and the number of carbon atoms at the terminal of a side chain of the carboxylic acid vinyl unit is 2-7.