Abstract:
Provided are systems and methods for noninvasively assessing intracranial pressure by controllably applanating at least a portion of a subject's ocular globe so as to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, as well as methods of assessing intracranial pressure that are based, at least in part, on the degree of papilledema, if any, present in the subject.
Abstract:
Provided are devices and methods for controlling fluid egress from the eye during ocular surgery, including an ocular seal that is signed to fit in an incision in an eye tissue such as the cornea or sclera and includes one or more lumen for passage of instruments into the eye without permitting loss of fluids through the incision. Also provided is a system for cataract surgery including a globe stabilization device, a laser lens removal device, one or more corneal seals, an infusion line, and an anterior chamber pressure monitor.
Abstract:
Provided are systems and methods for noninvasively assessing intracranial pressure by controllably osculating at least a portion of a subject's ocular globe while applying a force sufficient to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, such as retinal, corneal, and pupil imaging. The components may include an optical contact surface that has a radius of curvature that is greater than the radius of curvature of a subject's cornea.
Abstract:
A probe for medical use includes a tip portion having a light energy input region for receiving light energy from a light source and a predetermined light energy output region whereby tissue subtended by the region may be irradiated by the light energy. The tip portion consists essentially of light propagating material having inclusions distributed therein for interacting with the light energy to produce a predetermined light energy output pattern. The light propagating material is a light propagating inorganic compound.
Abstract:
The present invention is directed to a cladded optical fiber and a process for manufacturing the same. The cladding and core are halide materials. An interface for inhibiting radiation scatter is provided at the boundary between the halide cladding and the halide core. The process steps include extruding a first halide or halide core from a first chamber, and extruding a second halide or halide cladding from a second chamber into contact with the halide core. The halide cladding is joined to the halide core at the boundary.
Abstract:
Disclosed herein are medical devices for diagnosing and treating anomalous tissue and methods of use. One embodiment of the medical device can comprise an energy source configured to emit at least an excitation beam and a therapeutic beam, a probe coupled to the energy source and configured to propagate the excitation and therapeutic beams with the beams capable of contact with the tissue, a sensor coupled to the probe that detects at least one predefined attribute of radiation emanating from the tissue when the tissue is subjected to the excitation beam and a controller coupled to the energy source and the sensor and programmed to selectively alternatively actuate the energy source to emit the excitation beam and the therapeutic beam in response to the detection of the at least one predefined attribute by the sensor.
Abstract:
A probe for medical use includes a tip portion having a light energy input region for receiving light energy from a light source and a predetermined light energy output region whereby tissue subtended by the region may be irradiated by the light energy. The tip portion consists essentially of light propagating material having inclusions distributed therein and generally throughout the tip portion between the light energy input region and the light energy output region for interacting with the light energy to produce a predetermined light energy output pattern. The light propagating material is a light propagating inorganic compound.
Abstract:
The present invention is directed to a process for manufacturing a cladded optical fiber. The cladding and core are halide materials. An interface for inhibiting radiation scatter is provided at the boundary between the halide cladding and the halide core. The process steps include extruding a first halide or halide core from a first chamber, and extruding a second halide or halide cladding from a second chamber into contact with the halide core. The halide cladding is joined to the halide core at the boundary.
Abstract:
The method comprises inserting an optical detector into a movable holder, illuminating the optical detector by a source of optical energy to cause the detector to generate an output representative of intensity of illumination incident on the detector, moving a selected one of the source and holder to a position in which the output of the detector corresponds to maximum intensity of illumination, maintaining the moved one of the source and holder in said position and replacing the optical detector by a fiber optic to be aligned. The apparatus comprises a holder, a light source, and optical detector removably mounted in the holder for illumination by the light source, a circuit connected to output of the optical detector for determining when the output of the optical detector corresponds to maximum intensity of illumination, and means for moving a selected one of the holder and light source to a position in which the output of the detector corresponds to maximum intensity of illumination.