公开(公告)号：GB2118172A

公开(公告)日：1983-10-26

申请号：GB8302225

申请日：1983-01-27

Applicant: UBE INDUSTRIES

Inventor： FUJII KOZO ,  NISHIHIRA KEIGO ,  SAWADA HIROYUKI ,  TANAKA SHUJI ,  NAKAI MAMORU ,  INOUE TERUHIKO ,  YOSHIDA HIROSHI ,  OOMORI KIYOSI

IPC: C07D239/42

Abstract: A process for the preparation of a 2-alkyl-4-amino-5-aminomethyl pyrimidine comprises subjecting a 2- alkyl-4-amino-5-formylpyrimidine to catalytic reaction with hydrogen and ammonia in the presence of a reduction catalyst. The product is obtained in much higher yield than in known processes.

公开(公告)号：DE3303789A1

公开(公告)日：1983-08-11

申请号：DE3303789

申请日：1983-02-04

Applicant: UBE INDUSTRIES

Inventor： FUJII KOZO ,  NISHIHIRA KEIGO ,  SAWADA HIROYUKI ,  TANAKA SHUJI ,  NAKAI MAMORU ,  YOSHIDA HIROSHI ,  INOUE TERUHIKO ,  OOMORI KIYOSI

IPC: C07D239/42

公开(公告)号：DE3015834A1

公开(公告)日：1981-07-02

申请号：DE3015834

申请日：1980-04-24

Applicant: UBE INDUSTRIES

Inventor： NAKAI MAMORU ,  HARADA KATSUMASA ,  MORI YOSHIKATSU

IPC: C07D285/06

Abstract: There is provided a process for preparing a 5-amino-1,2,3-thiadiazole represented by the formula wherein R represents a hydrogen atom, a lower alkyl group or an aryl group, which comprises bringing a diazoacetonitrile represented by the formula wherein R has the same meaning as defined above, into contact with hydrogen sulfide in the presence of a base or with a salt of hydrogen sulfide, in a solvent.

公开(公告)号：DK159432C

公开(公告)日：1991-03-18

申请号：DK342383

申请日：1983-07-26

Applicant: UBE INDUSTRIES

Inventor： FUJII KOZO ,  NISHIHIRA KEIGO ,  SAWADA HIROYUKI ,  TANAKA SHUJI ,  NAKAI MAMORU ,  YOSHIDA HIROSHI ,  INOUE TERUHIKO

IPC: C07C255/15 ,  C07C67/00 ,  C07C253/00 ,  C07D239/24 ,  C07D239/42

Abstract: There are disclosed a process for preparing a 4-amino-5-dialkoxymethylpyrimidine derivative of the formula: which comprises subjecting a propanenitrile derivative represented by the formula (I) or (II) to reaction with an amidine of the formula wherein all the R to R are as defined in the specification; and a novel starting compound of the above formula (II) useful for the process.

公开(公告)号：CH654299A5

公开(公告)日：1986-02-14

申请号：CH61683

申请日：1983-02-03

Applicant: UBE INDUSTRIES

Inventor： FUJII KOZO ,  NISHIHIRA KEIGO ,  SAWADA HIROYUKI ,  TANAKA SHUJI ,  NAKAI MAMORU ,  YOSHIDA HIROSHI ,  INOUE TERUHIKO

IPC: C07D239/42 ,  C07D317/32 ,  C07C121/34

公开(公告)号：DE3163488D1

公开(公告)日：1984-06-14

申请号：DE3163488

申请日：1981-06-18

Applicant: UBE INDUSTRIES

Inventor： NAKAI MAMORU ,  OHSHIMA TOKIO ,  KIMURA TOMIO ,  OMATA TETSUO ,  IWAMOTO NORITADA

IPC: C12N9/80 ,  C12P13/04 ,  C12P13/22 ,  C12P41/00 ,  C12R1/025 ,  C12R1/05 ,  C12R1/06 ,  C12R1/07 ,  C12R1/13 ,  C12R1/145 ,  C12R1/20 ,  C12R1/225 ,  C12R1/265 ,  C12R1/32 ,  C12R1/365 ,  C12R1/38 ,  C12R1/46 ,  C12R1/465 ,  C12R1/645 ,  C12R1/65 ,  C12R1/66 ,  C12R1/72 ,  C12R1/77 ,  C12R1/78 ,  C12R1/80 ,  C12R1/84 ,  C12R1/845 ,  C12R1/85 ,  C12R1/88 ,  C12R1/885 ,  C07B19/02

Abstract: Biochemical optical resolution of DL-tryptophanes in which DL-tryptophane amides are interacted with the culture products, of their treated products, of a microorganism capable of producing amidase is described. L-tryptophane amides in racemic DL-tryptophane amides are asymmetrically hydrolyzed to form optically active L-tryptophanes at a high yield and almost all D-tryptophane amides remain without being subjected to hydrolysis. The resultant D-tryptophane amides are readily hydrolyzed, after separating L-tryptophanes, to form optically active D-tryptophanes at a high yield.

公开(公告)号：DK342383A

公开(公告)日：1984-03-11

申请号：DK342383

申请日：1983-07-26

Applicant: UBE INDUSTRIES

Inventor： FUJII KOZO ,  NISHIHIRA KEIGO ,  SAWADA HIROYUKI ,  TANAKA SHUJI ,  NAKAI MAMORU ,  YOSHIDA HIROSHI ,  INOUE TERUHIKO

IPC: C07C255/15 ,  C07C67/00 ,  C07C253/00 ,  C07D239/24 ,  C07D239/42 ,  C07D ,  C07C

Abstract: There are disclosed a process for preparing a 4-amino-5-dialkoxymethylpyrimidine derivative of the formula: which comprises subjecting a propanenitrile derivative represented by the formula (I) or (II) to reaction with an amidine of the formula wherein all the R to R are as defined in the specification; and a novel starting compound of the above formula (II) useful for the process.

公开(公告)号：DK357083D0

公开(公告)日：1983-08-04

申请号：DK357083

申请日：1983-08-04

Applicant: UBE INDUSTRIES

Inventor： NAKAI MAMORU ,  ENOMIYA TAKUJI

IPC: C07C20060101 ,  C07D20060101 ,  C07C49

公开(公告)号：DK342283D0

公开(公告)日：1983-07-26

申请号：DK342283

申请日：1983-07-26

Applicant: UBE INDUSTRIES

Inventor： FUJII KOZO ,  NISHIHIRA KEIGO ,  SAWADA HIROYUKI ,  TANAKA SHUJI ,  NAKAI MAMORU ,  YOSHIDA HIROSHI ,  INOUE TERUHIKO ,  OOMORI KIYOSI

IPC: C07D239/24 ,  A01N43/54 ,  C07D20060101 ,  C07D239/02 ,  C07D239/42 ,  C07D239

公开(公告)号：DE3218068A1

公开(公告)日：1982-12-09

申请号：DE3218068

申请日：1982-05-13

Applicant: UBE INDUSTRIES

Inventor： UMEMURA SUMIO ,  FUJII KOZO ,  NISHIHIRA KEIGO ,  SAWADA HIROYUKI ,  TANAKA SHUJI ,  NAKAI MAMORU ,  YOSHIDA HIROSHI ,  KUROKI YOSHIAKI

IPC: C07D319/06

Abstract: There are disclosed a 4-alkoxy-1,3-dioxane-5-carbonitrile which is a novel compound represented by the formula wherein R represents a lower-alkyl group, and which is useful as an intermediate for the synthesis of Vitamin B1, and a process for preparing the novel compound by subjecting a 3-alkoxy-2-propenenitrile to reaction with a formaldehyde in the presence of an acid catalyst.