Abstract:
This disclosure generally relates to at least one reusable module of a sorbent cartridge in a sorbent dialysis system. One of the drawbacks of a conventional sorbent dialysis system is the high cost. In one aspect of the invention, the sorbent cartridge contains at least one module for optionally recharging sorbent materials in-line, including zirconium phosphate, with an optional bypass and conduits for the sorbent cartridge. The sorbent cartridge can have two or more modules that are connected to one another through connectors. The modules can be reusable and the sorbent materials contained in the modules can be recharged, which reduce the cost of the sorbent dialysis system.
Abstract:
Methods and systems for employing softened acidified water sources from an acid regenerated ion exchange resins are disclosed. Various methods of dispensing and/or using the softened acidic water generated by an acid regenerate-able ion exchange resin are disclosed to beneficially reduce spotting, filming and scale buildup on treated surfaces, reduce and/or eliminate the need for polymers, including water conditioning agents, threshold reagents and/or rinse aids, and using protons generated in the acidic water effluent for triggering events useful in various cleaning applications.
Abstract:
High resolution protein A chromatography employing a chaotropic agent and pH gradient or pH step elution buffer results in improved peak resolution between closely related molecular species. Bispecific antibodies containing a protein A-binding-ablating substitution CH3 domain paired with a protein A-binding CH3 domain are separated with high peak resolution from monospecific antibodies containing a protein A-binding-ablating substituted CH3 domain paired with the protein A-binding-ablating substituted CH3 domain and monospecific antibodies containing a protein A-binding CH3 domain paired with the protein A-binding CH3 domain. Useful chaotropic agents include magnesium chloride and calcium chloride.
Abstract:
The present invention is generally directed to a versatile fluid treatment system which includes: a mobile device; a track system connected to the mobile device; one or more treatment vessels removably attached to the track system, each treatment vessel comprising a treatment material disposed inside the treatment vessel, at least one fluid inlet, and at least one fluid outlet; an input conduit that receives a fluid to be treated, the input conduit in fluid communication with the fluid inlet on the treatment vessel; and an output conduit in fluid communication with the fluid outlet on the treatment vessel, the output conduit receives treated fluid from the treatment vessels via the fluid outlet.
Abstract:
In one embodiment, the invention is to an ion exchange resin composition comprising a metal-functionalized exchange resin comprising from 3% to 94% metal-functionalized active sites; and a non-metal-functionalized exchange resin comprising non-metal-functionalized active sites.